在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human T-box transcription factor TBX4 (TBX4)

  • 中文名稱(chēng):
    人TBX4重組蛋白
  • 貨號(hào):
    CSB-YP023256HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    人TBX4重組蛋白
  • 貨號(hào):
    CSB-EP023256HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    人TBX4重組蛋白
  • 貨號(hào):
    CSB-EP023256HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    人TBX4重組蛋白
  • 貨號(hào):
    CSB-BP023256HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    人TBX4重組蛋白
  • 貨號(hào):
    CSB-MP023256HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TBX4
  • Uniprot No.:
  • 別名:
    SPS; T box 4 ; T box protein 4; T box transcription factor TBX 4; T box transcription factor TBX4; T-box protein 4; T-box transcription factor TBX4; TBX 4; TBX4; TBX4_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-545
  • 氨基酸序列
    MLQDKGLSES EEAFRAPGPA LGEASAANAP EPALAAPGLS GAALGSPPGP GADVVAAAAA EQTIENIKVG LHEKELWKKF HEAGTEMIIT KAGRRMFPSY KVKVTGMNPK TKYILLIDIV PADDHRYKFC DNKWMVAGKA EPAMPGRLYV HPDSPATGAH WMRQLVSFQK LKLTNNHLDP FGHIILNSMH KYQPRLHIVK ADENNAFGSK NTAFCTHVFP ETSFISVTSY QNHKITQLKI ENNPFAKGFR GSDDSDLRVA RLQSKEYPVI SKSIMRQRLI SPQLSATPDV GPLLGTHQAL QHYQHENGAH SQLAEPQDLP LSTFPTQRDS SLFYHCLKRR DGTRHLDLPC KRSYLEAPSS VGEDHYFRSP PPYDQQMLSP SYCSEVTPRE ACMYSGSGPE IAGVSGVDDL PPPPLSCNMW TSVSPYTSYS VQTMETVPYQ PFPTHFTATT MMPRLPTLSA QSSQPPGNAH FSVYNQLSQS QVRERGPSAS FPRERGLPQG CERKPPSPHL NAANEFLYSQ TFSLSRESSL QYHSGMGTVE NWTDG
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
  • 基因功能參考文獻(xiàn):
    1. We propose phenotypic expansion of the TBX4-related clinical disease spectrum to include acinar dysplasia of the lungs. The reported mutation is the first identified genetic variant causative for acinar dysplasia. PMID: 27374786
    2. TBX4 is a mesenchymal transcription factor that drives accumulation of myofibroblasts and the development of lung fibrosis PMID: 27400124
    3. In a cohort with idiopathic or hereditary pulmonary arterial hypertension, a possibly associated mutation was found in 11.10% of the idiopathic cases (n = 16) and in 68.18% of the hereditary cases. There were 4 mutations found in TBX4. PMID: 27453251
    4. a low level of TBX4 expression suggests a worse prognosis for patients with stage II PDAC. Down-regulation of the TBX4 gene in pancreas is less likely to be regulated by DNA methylation. PMID: 21954337
    5. Although TBX4 remains the candidate gene for congenital clubfoot involving 17q23.1-q23.2 duplications, the explanation for variable expressivity and penetrance remains unknown. PMID: 24592505
    6. data indicate that TBX4 mutations are associated with childhood-onset pulmonary arterial hypertension (PAH), but the prevalence of PAH in adult TBX4 mutation carriers is low PMID: 23592887
    7. Minimal evidence was found for an association between TBX4 and clubfoot and no pathogenic sequence variants were identified in the two known TBX4 hindlimb enhancer elements. PMID: 22678995
    8. Microdeletion of 17q22q23.2 encompassing TBX2 and TBX4 in a patient with congenital microcephaly, thyroid duct cyst, sensorineural hearing loss, and pulmonary hypertension. PMID: 21271665
    9. Mutations in the human TBX4 gene cause small patella syndrome PMID: 15106123

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Ischiocoxopodopatellar syndrome (ICPPS)
  • 亞細(xì)胞定位:
    Nucleus.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 11603

    OMIM: 147891

    KEGG: hsa:9496

    STRING: 9606.ENSP00000240335

    UniGene: Hs.143907



主站蜘蛛池模板: 非洲黑人最猛性xxxx交| 国产无遮挡a片无码免费软件| 日日天干夜夜狠狠爱| 亚洲精品无码久久久久| 青青久在线视观看视| 精品国产乱码久久久软件下载| 国产高清自产拍av在线| 一本一道波多野结衣av黑人| 思思99re6国产在线播放| 亚洲国产精品无码av| 肥臀熟女一区二区三区| 久久久精品人妻久久影视| 亚洲色无码专区在线播放| 日本乱理伦片在线观看中文| 成人试看120秒体验区| 国精产品999国精产| 亚洲精品一区二区三区麻豆| 亚洲成av人片在线观l看福利1| 国产精品久久一区二区三区| 国产伦子沙发午休系列资源曝光| 亚洲国产成av人天堂无码 | 全黄性性激高免费视频| 亚洲国产精品久久久天堂麻豆宅男| 无码人妻丝袜视频在线播免费| 国产乱人伦精品免费| 亚洲乱码精品久久久久.. | 日产亚洲一区二区三区| 无码精品日韩专区| 插一插射一射视频| 精品久久久久久成人av| 亚州中文字幕无码中文字幕| 亚洲欲色欲色xxxxx在线| 色婷婷综合中文久久一本| 婷婷色香合缴缴情av第三区| 久久国产欧美成人网站| 内射少妇一区27p| 国产aⅴ激情无码久久久无码| 被窝的午夜无码福利专区| 欧美人与动另类xxxx| 国产99在线 | 亚洲| 性中国妓女毛茸茸视频|