在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TBX4 Antibody, Biotin conjugated

  • 中文名稱:
    TBX4兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA023256LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TBX4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TBX4
  • 別名:
    SPS antibody; T box 4 antibody; T box protein 4 antibody; T box transcription factor TBX 4 antibody; T box transcription factor TBX4 antibody; T-box protein 4 antibody; T-box transcription factor TBX4 antibody; TBX 4 antibody; TBX4 antibody; TBX4_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human T-box transcription factor TBX4 protein (355-511AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
  • 基因功能參考文獻:
    1. We propose phenotypic expansion of the TBX4-related clinical disease spectrum to include acinar dysplasia of the lungs. The reported mutation is the first identified genetic variant causative for acinar dysplasia. PMID: 27374786
    2. TBX4 is a mesenchymal transcription factor that drives accumulation of myofibroblasts and the development of lung fibrosis PMID: 27400124
    3. In a cohort with idiopathic or hereditary pulmonary arterial hypertension, a possibly associated mutation was found in 11.10% of the idiopathic cases (n = 16) and in 68.18% of the hereditary cases. There were 4 mutations found in TBX4. PMID: 27453251
    4. a low level of TBX4 expression suggests a worse prognosis for patients with stage II PDAC. Down-regulation of the TBX4 gene in pancreas is less likely to be regulated by DNA methylation. PMID: 21954337
    5. Although TBX4 remains the candidate gene for congenital clubfoot involving 17q23.1-q23.2 duplications, the explanation for variable expressivity and penetrance remains unknown. PMID: 24592505
    6. data indicate that TBX4 mutations are associated with childhood-onset pulmonary arterial hypertension (PAH), but the prevalence of PAH in adult TBX4 mutation carriers is low PMID: 23592887
    7. Minimal evidence was found for an association between TBX4 and clubfoot and no pathogenic sequence variants were identified in the two known TBX4 hindlimb enhancer elements. PMID: 22678995
    8. Microdeletion of 17q22q23.2 encompassing TBX2 and TBX4 in a patient with congenital microcephaly, thyroid duct cyst, sensorineural hearing loss, and pulmonary hypertension. PMID: 21271665
    9. Mutations in the human TBX4 gene cause small patella syndrome PMID: 15106123

    顯示更多

    收起更多

  • 相關疾病:
    Ischiocoxopodopatellar syndrome (ICPPS)
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 11603

    OMIM: 147891

    KEGG: hsa:9496

    STRING: 9606.ENSP00000240335

    UniGene: Hs.143907



主站蜘蛛池模板: 久久香蕉超碰97国产精品| 特级aaaaaaaaa毛片免费视频| 性欧美大胆免费播放| 久久精品麻豆日日躁夜夜躁| 高清无码视频直接看| 国产日产欧产精品| 日韩精品人妻无码久久影院| 手机在线亚洲国产精品| 国产成人精品免高潮在线观看| 天天躁日日躁狠狠躁欧美老妇| 免费观看的av在线播放| 国产粉嫩小泬在线观看泬| 亚洲欧美日韩国产自偷| 超碰97久久国产精品牛牛| 特级毛片爽www免费版| 香蕉精品亚洲二区在线观看| 国产精品久免费的黄牛仔短裤| 日本无码人妻一区二区色欲| 精品久久久久久人妻无码中文字幕 | а√天堂8资源中文在线| 国内精品美女a∨在线播放| 国产网曝门亚洲综合在线| 风流少妇又紧又爽又丰满| 亚洲男女羞羞无遮挡久久丫| 国产做爰又粗又大又爽动漫| 天下第一社区视频www日本| 人妻三级日本香港三级极97| 亚洲成a∨人片在线观看不卡 | 国内精品久久久久久久电影视| 色吊丝中文字幕| 人妻 日韩精品 中文字幕| 看成年全黄大色黄大片| 欧美老妇疯狂xxxxbbbb| 青青草原综合久久大伊人| 国产亚洲精品久久久久久| 免费无码av片在线观看动漫| 精品999日本久久久影院| 色综合久久久久久久久五月| 18禁成人网站免费观看| 亚洲国产av玩弄放荡人妇| 亚洲国产成人久久一区|