在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Syntaxin-binding protein 4 (STXBP4)

  • 中文名稱:
    人STXBP4重組蛋白
  • 貨號:
    CSB-YP757971HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人STXBP4重組蛋白
  • 貨號:
    CSB-EP757971HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人STXBP4重組蛋白
  • 貨號:
    CSB-EP757971HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人STXBP4重組蛋白
  • 貨號:
    CSB-BP757971HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人STXBP4重組蛋白
  • 貨號:
    CSB-MP757971HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    STXBP4
  • Uniprot No.:
  • 別名:
    FLJ16496; MGC149829; MGC50337; OTTHUMP00000082667; OTTHUMP00000227400; STX4-interacting protein; STXB4_HUMAN; Stxbp4; Synip; Syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin binding protein 4; Syntaxin-binding protein 4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-553
  • 氨基酸序列
    MNKNTSTVVS PSLLEKDPAF QMITIAKETG LGLKVLGGIN RNEGPLVYIQ EIIPGGDCYK DGRLKPGDQL VSVNKESMIG VSFEEAKSII TGAKLRLESA WEIAFIRQKS DNIQPENLSC TSLIEASGEY GPQASTLSLF SSPPEILIPK TSSTPKTNND ILSSCEIKTG YNKTVQIPIT SENSTVGLSN TDVASAWTEN YGLQEKISLN PSVRFKAEKL EMALNYLGIQ PTKEQHQALR QQVQADSKGT VSFGDFVQVA RNLFCLQLDE VNVGAHEISN ILDSQLLPCD SSEADEMERL KCERDDALKE VNTLKEKLLE SDKQRKQLTE ELQNVKQEAK AVVEETRALR SRIHLAEAAQ RQAHGMEMDY EEVIRLLEAK ITELKAQLAD YSDQNKESVQ DLKKRIMVLD CQLRKSEMAR KTFEASTEKL LHFVEAIQEV FSDNSTPLSN LSERRAVLAS QTSLTPLGRN GRSIPATLAL ESKELVKSVR ALLDMDCLPY GWEEAYTADG IKYFINHVTQ TTSWIHPVMS VLNLSRSEEN EEDCSRELPN QKS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
  • 基因功能參考文獻:
    1. High STXBP4 expression is associated with squamous cell carcinogenesis. PMID: 29735662
    2. The deleterious SNPs localized in STXBP4 and ZNF404 genes were identified which might play a role in breast cancer development by dysregulating its gene expression. PMID: 28422318
    3. Expression studies in breast tumor tissues found SNP rs2787486 to be associated with increased STXBP4 expression, suggesting this may be a target gene of this locus. PMID: 27600471
    4. Whole transcriptome sequencing followed by pathway analysis indicated that STXBP4 is involved in functional gene networks that regulate cell growth, proliferation, cell death, and survival in cancer. Platelet-derived growth factor receptor alpha (PDGFRalpha) was a key downstream mediator of STXBP4 function. In line with this, shRNA mediated STXBP4 and PDGFRA knockdown suppressed tumor growth in soft-agar and xenograft ... PMID: 28087642
    5. meta-analysis suggested that polymorphism STXBP4/COX11 rs6504950 variant was significantly associated with breast cancer risk; the A allele of rs6504950 decreased the risk of breast cancer PMID: 22863968
    6. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
    7. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20095854
    8. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20145138
    9. Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cells PMID: 12855681
    10. Stxbp4 and RACK1, two scaffold proteins, play central roles in balancing DeltaNp63 protein levels. While Stxbp4 functions to stabilize DeltaNp63 proteins, RACK1 targets DeltaNp63 for degradation. PMID: 19451233

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 19694

    OMIM: 610415

    KEGG: hsa:252983

    STRING: 9606.ENSP00000365530

    UniGene: Hs.35199



主站蜘蛛池模板: 国产精品点击进入在线影院高清| 人妻丰满av无码久久不卡| 国产精品久久久亚洲| 日产乱码一区二区三区在线| 少妇无码av无码专区线y| 国产疯狂伦交大片| 国产97在线 | 中文| 日本高清一二三不卡区| 欧美性色老妇人| 亚洲成av人片在线观看天堂无码| 边添小泬边狠狠躁视频| 国产成人亚洲精品另类动态 | 无码国产69精品久久久久网站| 蜜芽久久人人超碰爱香蕉| 99久久精品免费看国产一区二区| 国产乱子伦精品免费视频| 麻豆md0077饥渴少妇| 欧美性大战久久久久久| 天天澡日日澡狠狠欧美老妇| 成人美女黄网站色大色费全看| 中文字幕精品亚洲人成在线| 久久精品无码精品免费专区| 国产无套内射又大又猛又粗又爽 | 成人综合婷婷国产精品久久| 国产日韩未满十八禁止观看| 五月丁香综合激情六月久久 | 久热这里只有精品99| 好硬好湿好爽再深一点动态图视频| 天天躁日日躁很很很躁| 欧美极品video粗暴| 任我爽橹在线精品视频| 第九色区av天堂| 综合三区后入内射国产馆| 夜精品一区二区无码a片| 中文字幕av无码一区二区三区电影| 亚洲妇熟xxxx妇色黄| 国产在线高清亚洲精品二区| 五十路熟妇高熟无码视频 | 天堂а√中文最新版地址在线| 中文国产成人精品久久久| 五月天中文字幕mv在线|