在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STXBP4 Antibody

STXBP4 Antibody

  • 中文名稱：
    STXBP4兔多克隆抗體
  • 貨號：
    CSB-PA022908GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    STXBP4
  • 別名：
    FLJ16496 antibody; MGC149829 antibody; MGC50337 antibody; OTTHUMP00000082667 antibody; OTTHUMP00000227400 antibody; STX4-interacting protein antibody; STXB4_HUMAN antibody; Stxbp4 antibody; Synip antibody; Syntaxin 4 interacting protein antibody; Syntaxin 4-interacting protein antibody; Syntaxin binding protein 4 antibody; Syntaxin-binding protein 4 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human STXBP4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
  • 基因功能參考文獻：
    1. High STXBP4 expression is associated with squamous cell carcinogenesis. PMID: 29735662
    2. The deleterious SNPs localized in STXBP4 and ZNF404 genes were identified which might play a role in breast cancer development by dysregulating its gene expression. PMID: 28422318
    3. Expression studies in breast tumor tissues found SNP rs2787486 to be associated with increased STXBP4 expression, suggesting this may be a target gene of this locus. PMID: 27600471
    4. Whole transcriptome sequencing followed by pathway analysis indicated that STXBP4 is involved in functional gene networks that regulate cell growth, proliferation, cell death, and survival in cancer. Platelet-derived growth factor receptor alpha (PDGFRalpha) was a key downstream mediator of STXBP4 function. In line with this, shRNA mediated STXBP4 and PDGFRA knockdown suppressed tumor growth in soft-agar and xenograft ... PMID: 28087642
    5. meta-analysis suggested that polymorphism STXBP4/COX11 rs6504950 variant was significantly associated with breast cancer risk; the A allele of rs6504950 decreased the risk of breast cancer PMID: 22863968
    6. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
    7. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20095854
    8. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20145138
    9. Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cells PMID: 12855681
    10. Stxbp4 and RACK1, two scaffold proteins, play central roles in balancing DeltaNp63 protein levels. While Stxbp4 functions to stabilize DeltaNp63 proteins, RACK1 targets DeltaNp63 for degradation. PMID: 19451233

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19694

    OMIM: 610415

    KEGG: hsa:252983

    STRING: 9606.ENSP00000365530

    UniGene: Hs.35199



主站蜘蛛池模板： av蓝导航精品导航| 久9re热视频这里只有精品| 伊人色合天天久久综合网| 狠狠色狠狠色综合网| 奇米影视777四色米奇影院| 无码av片av片av无码| 亚洲精品无码久久久久av老牛| 永久免费看啪啪网址入口| 国产成人av无码精品| 伊人亚洲综合影院首页| 日本在线a一区视频高清视频| 免费人成小说在线观看网站| 精品黑人一区二区三区久久| 天天爱天天做天天爽夜夜揉 | 亚洲性人人天天夜夜摸18禁止 | 无码人妻一区二区三区免费视频| 任我爽精品视频在线观看| 99精品视频在线观看免费蜜桃| 一边吃奶一边摸做爽视频| 亚洲国产精品久久久久爰色欲| 韩国无码av片在线观看| 欧美巨大xxxx做受中文字幕| 精品亚洲麻豆1区2区3区| 国内揄拍国产精品人妻门事件| 欧美最猛性xxxxx大叫| 国产青榴视频在线观看| 在线天堂中文在线资源网| 色欲αv一区二区三区天美传媒| 欧美大香线蕉线伊人久久| 色婷婷欧美在线播放内射| 色狠狠一区二区三区香蕉| 综合精品欧美日韩国产在线| 中文字幕乱码免费| 色一情一乱一伦一视频免费看| 美女裸奶100%无遮挡免费网站| 吃奶呻吟张开双腿做受在线播放| 亚洲熟妇色自偷自拍另类| 国产精品沙发系列| 国内精品久久久久久影院8f| 色天使久久综合网天天| 亚洲欧美日韩综合久久久|