在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Sodium-dependent phosphate transporter 1 (SLC20A1), partial

Recombinant Human Sodium-dependent phosphate transporter 1 (SLC20A1), partial

  • 中文名稱：
    人SLC20A1重組蛋白
  • 貨號：
    CSB-YP823882HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SLC20A1重組蛋白
  • 貨號：
    CSB-EP823882HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SLC20A1重組蛋白
  • 貨號：
    CSB-EP823882HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SLC20A1重組蛋白
  • 貨號：
    CSB-BP823882HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SLC20A1重組蛋白
  • 貨號：
    CSB-MP823882HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    DKFZp686J2397; FLJ41426; Gibbon ape leukemia virus receptor 1; GLVR 1; GLVR-1; GLVR1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; PIT 1; PiT-1; PIT1; S20A1_HUMAN; Slc20a1; Sodium dependent phosphate transporter 1; Sodium-dependent phosphate transporter 1; Solute carrier family 20 (phosphate transporter) member 1; Solute carrier family 20 member 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification.; (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).
  • 基因功能參考文獻：
    1. Targeted sequencing of two candidate genes, SLC20A1 and SLC15A4, of the solute carrier membrane transport protein family in 200 additional patients demonstrated two further variants predicted as damaging for combined hormone deficiency. PMID: 29261175
    2. Overexpression of SLC20A1 is associated with Estrogen Receptor-positive Breast Cancer. PMID: 27986439
    3. indoxyl sulfate promotes Pit-1 expression in part by activation of the JNK pathway in vascular smooth muscle cells PMID: 27001263
    4. Ox-LDL induces an osteogenic change in human aortic valve interstitial cells marked by the induction of PiT-1. PMID: 23849774
    5. Overexpression of SLC20A1 promotes apoptosis and mineralization by altering the level of Akt-1. PMID: 23308213
    6. Allelic variations in SLC20A1 were associated with the levels of Sodium-lithium countertransport. PMID: 21796222
    7. the human PiT2 histidine, H(502), and the human PiT1 glutamate, E(70),--both conserved in eukaryotic PiT family members--are critical for P(i) transport function PMID: 21586110
    8. Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis. PMID: 20817733
    9. propose that region A of Pit1 confers competence for viral entry by influencing the topology of the authentic binding site in the membrane and hence its accessibility to a viral envelope protein PMID: 12097582
    10. Two highly conserved glutamate residues critical for sodium-dependent phosphate transport are revealed by uncoupling transport function from retroviral receptor function. PMID: 12205090
    11. Our results link low-grade IL-8-mediated cartilaginous inflammation in OA to altered chondrocyte differentiation and disease progression through PiT-1 expression and sodium-dependent Pi uptake mediated by CXCR1 signaling. PMID: 15641067
    12. Phosphate uptake through Pit-1 is essential for vascular smooth muscle cell calcification and phenotypic modulation in response to elevated phosphate. PMID: 16527991
    13. Results describe the characterization of transport mechanisms and determinants critical for sodium-dependent phosphate symport of the PiT family paralogs human PiT1 and PiT2. PMID: 16790504
    14. Analysis of kinetics and substrate specificity of SLC20A1. PMID: 17494632
    15. An overexpression of Pit-1 seems to play a key role in the formation of soft tissue calcification in Werner syndrome. PMID: 18729813
    16. PiT1 depletion markedly reduces cell proliferation, delays cell cycle, and impairs mitosis and cytokinesis. PMID: 19726692

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Inorganic phosphate transporter (PiT) (TC 2.A.20) family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 10946

    OMIM: 137570

    KEGG: hsa:6574

    STRING: 9606.ENSP00000272542

    UniGene: Hs.187946



主站蜘蛛池模板： 国产成人欧美亚洲日韩电影| 无遮挡又黄又刺激的视频| 亚洲国产精品毛片av不卡在线| 一本久久知道综合久久| 女人下边被添全过视频的网址| 国产乱对白刺激视频| 天天看片天天av免费观看 | 免费人成在线观看| 亚洲国产成人久久一区www| 国产精品毛片av在线看| 精品国产一区二区三区久久狼| 国内午夜熟妇又乱又伦| 无码aⅴ精品一区二区三区| 国产精品美女www爽爽爽视频| 亚洲国产综合av在线观看 | 亚洲欧美日韩国产综合在线一区| av无码久久久精品免费| 欧美人成精品网站播放| 中文字幕人成无码人妻综合社区| 久久国产劲爆∧v内射| 欧美大片18禁aaa免费视频| 性欧美俄罗斯乱妇| 无码国产一区二区免费| 性生交大片免费看女人按摩| 一本一道精品欧美中文字幕| 久久精品人人槡人妻人人玩av | 先锋影音男人av资源| 国产999精品久久久久久| 在线亚洲视频网站www色| 国色天香成人一区二区| 好大好硬好爽免费视频| 亚洲国产成人乱码| 日韩精品av一区二区三区| 无码东京热一区二区三区| 精品国产自在精品国产精华天| 久久午夜羞羞影院免费观看| 日韩人妻中文无码一区二区七区| 综合无码精品人妻一区二区三区| 综合图区亚洲欧美另类图片| 欧美日韩一区二区三区视频播放| 亚洲系列一区中文字幕|