在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC20A1 Antibody, HRP conjugated

  • 中文名稱:
    SLC20A1兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA823882LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SLC20A1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    DKFZp686J2397 antibody; FLJ41426 antibody; Gibbon ape leukemia virus receptor 1 antibody; GLVR 1 antibody; GLVR-1 antibody; GLVR1 antibody; Leukemia virus receptor 1 homolog antibody; Phosphate transporter 1 antibody; PIT 1 antibody; PiT-1 antibody; PIT1 antibody; S20A1_HUMAN antibody; Slc20a1 antibody; Sodium dependent phosphate transporter 1 antibody; Sodium-dependent phosphate transporter 1 antibody; Solute carrier family 20 (phosphate transporter) member 1 antibody; Solute carrier family 20 member 1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Sodium-dependent phosphate transporter 1 protein (263-458AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification.; (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).
  • 基因功能參考文獻(xiàn):
    1. Targeted sequencing of two candidate genes, SLC20A1 and SLC15A4, of the solute carrier membrane transport protein family in 200 additional patients demonstrated two further variants predicted as damaging for combined hormone deficiency. PMID: 29261175
    2. Overexpression of SLC20A1 is associated with Estrogen Receptor-positive Breast Cancer. PMID: 27986439
    3. indoxyl sulfate promotes Pit-1 expression in part by activation of the JNK pathway in vascular smooth muscle cells PMID: 27001263
    4. Ox-LDL induces an osteogenic change in human aortic valve interstitial cells marked by the induction of PiT-1. PMID: 23849774
    5. Overexpression of SLC20A1 promotes apoptosis and mineralization by altering the level of Akt-1. PMID: 23308213
    6. Allelic variations in SLC20A1 were associated with the levels of Sodium-lithium countertransport. PMID: 21796222
    7. the human PiT2 histidine, H(502), and the human PiT1 glutamate, E(70),--both conserved in eukaryotic PiT family members--are critical for P(i) transport function PMID: 21586110
    8. Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis. PMID: 20817733
    9. propose that region A of Pit1 confers competence for viral entry by influencing the topology of the authentic binding site in the membrane and hence its accessibility to a viral envelope protein PMID: 12097582
    10. Two highly conserved glutamate residues critical for sodium-dependent phosphate transport are revealed by uncoupling transport function from retroviral receptor function. PMID: 12205090
    11. Our results link low-grade IL-8-mediated cartilaginous inflammation in OA to altered chondrocyte differentiation and disease progression through PiT-1 expression and sodium-dependent Pi uptake mediated by CXCR1 signaling. PMID: 15641067
    12. Phosphate uptake through Pit-1 is essential for vascular smooth muscle cell calcification and phenotypic modulation in response to elevated phosphate. PMID: 16527991
    13. Results describe the characterization of transport mechanisms and determinants critical for sodium-dependent phosphate symport of the PiT family paralogs human PiT1 and PiT2. PMID: 16790504
    14. Analysis of kinetics and substrate specificity of SLC20A1. PMID: 17494632
    15. An overexpression of Pit-1 seems to play a key role in the formation of soft tissue calcification in Werner syndrome. PMID: 18729813
    16. PiT1 depletion markedly reduces cell proliferation, delays cell cycle, and impairs mitosis and cytokinesis. PMID: 19726692

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Inorganic phosphate transporter (PiT) (TC 2.A.20) family
  • 組織特異性:
    Ubiquitously expressed.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10946

    OMIM: 137570

    KEGG: hsa:6574

    STRING: 9606.ENSP00000272542

    UniGene: Hs.187946



主站蜘蛛池模板: 亚洲一区二区| 亚洲成av人片久久| 欧美xxxx黑人又粗又长精品| 男人女人午夜视频免费| 免费无码成人av在线播| 97人洗澡从澡人人爽人人模| 高清国产亚洲欧洲av综合一区| 噜噜高清欧美内射短视频| 热99re久久精品这里都是精品| 国产美女极度色诱视频www| 久久精品无码一区二区日韩av| 成 人 色综合 综合网站| 男女一边摸一边做爽爽的免费阅读| 久久久久高潮毛片免费全部播放| 久久久99精品免费观看| 无码人妻丰满熟妇精品区| 久久不见久久见免费视频6无删减| 亚洲va中文在线播放| 网禁拗女稀缺资源在线观看| 久久综合亚洲色一区二区三区 | 丁香色欲久久久久久综合网| 精品香蕉久久久午夜福利| 中文字幕精品亚洲无线码vr| 日本无码人妻一区二区色欲| 亚洲区日韩精品中文字幕| 色综合av综合无码综合网站| 国产成人精品无码一区二区三区| 国产很色很黄很大爽的视频| 亚洲日韩精品无码专区| 国精产品999国精产| 又粗又猛又黄又爽无遮挡| 亚洲精品国偷自产在线99人热| www夜片内射视频在观看视频| 精品国产乱码久久久久久免费| 亚洲vs日韩vs欧美vs久久| 色偷偷人人澡久久超碰97| 免费精品国产自在| 无码一区二区| 中文字幕一区二区人妻电影| 天天躁久久躁日日躁| 最新精品国偷自产在线美女足|