在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC20A1 Antibody, Biotin conjugated

SLC20A1 Antibody, Biotin conjugated

  • 中文名稱：
    SLC20A1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA823882LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC20A1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    DKFZp686J2397 antibody; FLJ41426 antibody; Gibbon ape leukemia virus receptor 1 antibody; GLVR 1 antibody; GLVR-1 antibody; GLVR1 antibody; Leukemia virus receptor 1 homolog antibody; Phosphate transporter 1 antibody; PIT 1 antibody; PiT-1 antibody; PIT1 antibody; S20A1_HUMAN antibody; Slc20a1 antibody; Sodium dependent phosphate transporter 1 antibody; Sodium-dependent phosphate transporter 1 antibody; Solute carrier family 20 (phosphate transporter) member 1 antibody; Solute carrier family 20 member 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sodium-dependent phosphate transporter 1 protein (263-458AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification.; (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).
  • 基因功能參考文獻：
    1. Targeted sequencing of two candidate genes, SLC20A1 and SLC15A4, of the solute carrier membrane transport protein family in 200 additional patients demonstrated two further variants predicted as damaging for combined hormone deficiency. PMID: 29261175
    2. Overexpression of SLC20A1 is associated with Estrogen Receptor-positive Breast Cancer. PMID: 27986439
    3. indoxyl sulfate promotes Pit-1 expression in part by activation of the JNK pathway in vascular smooth muscle cells PMID: 27001263
    4. Ox-LDL induces an osteogenic change in human aortic valve interstitial cells marked by the induction of PiT-1. PMID: 23849774
    5. Overexpression of SLC20A1 promotes apoptosis and mineralization by altering the level of Akt-1. PMID: 23308213
    6. Allelic variations in SLC20A1 were associated with the levels of Sodium-lithium countertransport. PMID: 21796222
    7. the human PiT2 histidine, H(502), and the human PiT1 glutamate, E(70),--both conserved in eukaryotic PiT family members--are critical for P(i) transport function PMID: 21586110
    8. Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis. PMID: 20817733
    9. propose that region A of Pit1 confers competence for viral entry by influencing the topology of the authentic binding site in the membrane and hence its accessibility to a viral envelope protein PMID: 12097582
    10. Two highly conserved glutamate residues critical for sodium-dependent phosphate transport are revealed by uncoupling transport function from retroviral receptor function. PMID: 12205090
    11. Our results link low-grade IL-8-mediated cartilaginous inflammation in OA to altered chondrocyte differentiation and disease progression through PiT-1 expression and sodium-dependent Pi uptake mediated by CXCR1 signaling. PMID: 15641067
    12. Phosphate uptake through Pit-1 is essential for vascular smooth muscle cell calcification and phenotypic modulation in response to elevated phosphate. PMID: 16527991
    13. Results describe the characterization of transport mechanisms and determinants critical for sodium-dependent phosphate symport of the PiT family paralogs human PiT1 and PiT2. PMID: 16790504
    14. Analysis of kinetics and substrate specificity of SLC20A1. PMID: 17494632
    15. An overexpression of Pit-1 seems to play a key role in the formation of soft tissue calcification in Werner syndrome. PMID: 18729813
    16. PiT1 depletion markedly reduces cell proliferation, delays cell cycle, and impairs mitosis and cytokinesis. PMID: 19726692

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Inorganic phosphate transporter (PiT) (TC 2.A.20) family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 10946

    OMIM: 137570

    KEGG: hsa:6574

    STRING: 9606.ENSP00000272542

    UniGene: Hs.187946



主站蜘蛛池模板： 日韩av高潮喷水在线观看| 中国女人内谢69xxxx视频| 激情综合五月| 少妇裸体性生交| 久久久精品久久日韩一区综合| 国产欧美va欧美va香蕉在| 四虎影视国产精品久久| 亚洲精品无码av中文字幕电影网站| 国产一区二区亚洲精品 | 99久久国产综合精品五月天| 国产免费一区二区三区在线观看 | 亚洲精品无码永久在线观看性色| 亚洲欧美中文日韩在线视频一 | 国产传媒精品1区2区3区| 亚洲成a人片在线观看无码专区| 四虎亚洲中文字幕无码永久| 亚洲精品久久中文字幕| 伊人久久大香线蕉精品| 国产精品免费久久久久影院仙踪林| 日韩欧美高清dvd碟片| av无码中文一区二区三区四区| 中文字幕乱码免费专区| 全国最大成人网| 国产成人av大片大片在线播放| 国产喷水1区2区3区咪咪爱av| 精品成人a区在线观看| 中文字幕韩国三级理论| 色噜噜av亚洲色一区二区| 国产精品18久久久| 伊人精品成人久久综合| 一区二区三区无码免费看| 国产成人无码性教育视频| 精品一卡二卡三卡| 亚洲日韩日本中文在线| 久久精品国产精品亚洲蜜月| 日出水了特别黄的视频| 人牛交vide欧美xxxx| 国产女主播白浆在线看| 欧美性猛交ⅹxxx乱大交妖精| 妇女性内射冈站hdwww000| 欧美大胆作爱视频欣赏人体|