在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), partial

Recombinant Human SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), partial

  • 中文名稱：
    人SHANK1重組蛋白
  • 貨號：
    CSB-YP897558HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SHANK1重組蛋白
  • 貨號：
    CSB-EP897558HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SHANK1重組蛋白
  • 貨號：
    CSB-EP897558HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SHANK1重組蛋白
  • 貨號：
    CSB-BP897558HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SHANK1重組蛋白
  • 貨號：
    CSB-MP897558HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    GKAP/SAPAP interacting protein; OTTHUMP00000174437; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHAN1_HUMAN; SHANK 1; Shank1; Shank1a; Somatostatin receptor interacting protein; Somatostatin receptor-interacting protein; SPANK 1; SPANK1; SSTR interacting protein; SSTR-interacting protein; SSTRIP; Synamon
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
  • 基因功能參考文獻：
    1. Authors summarize and discuss behavioral and neuronal findings obtained in the Shank1 knockout mouse model for Autism spectrum disorder (ASD); identify open research questions by comparing such findings with the symptoms present in humans diagnosed with ASD and carrying SHANK1 deletions; conclude by discussing the implications of the behavioral and neuronal phenotypes displayed by the Shank1 knockout mouse model. PMID: 28963042
    2. SHANK1 and SHANK3 act as integrin activation inhibitors by sequestering active Rap1 and R-Ras via the SPN domain and thus limiting their bioavailability at the plasma membrane. PMID: 28263956
    3. Data show that the Shank1 protein mRNA 3' UTR adopts two very stable intramolecular G-quadruplexes which are bound specifically and with high affinity by X mental retardation protein (FMRP). PMID: 25692235
    4. a non-canonical initiation site is required for efficient translation of the dendritically localized Shank1 mRNA PMID: 24533096
    5. The results of this study suggested a role of SHANK1 in working memory deficits in schizophrenia. PMID: 21901269
    6. A hemizygous SHANK1 deletion segregates in a four-generation family in which male carriers--but not female carriers--have autism spectrum disorder with higher functioning. PMID: 22503632
    7. Results show that dendritic targeting of shank1 mRNA granules involves KIF5C and the KIF5-associated RNA-binding protein staufen1. PMID: 19416473

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 蛋白家族：
    SHANK family
  • 組織特異性：
    Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus. Isoform 2 seems to be expressed ubiquitously.
  • 數據庫鏈接：

    HGNC: 15474

    OMIM: 604999

    KEGG: hsa:50944

    STRING: 9606.ENSP00000293441

    UniGene: Hs.274255



主站蜘蛛池模板： 天堂资源中文| 色老头精品午夜福利视频| 国产精品高潮呻吟av久久| 免费观看又色又爽又湿的视频| 熟妇高潮喷沈阳45熟妇高潮喷| 午夜福利理论片在线观看播放| 久久婷婷五月综合色国产香蕉 | 中文字幕无码日韩欧免费软件| 色偷偷亚洲精品一区二区| 英语老师丝袜娇喘好爽视频| 国产精品久久久福利| 亚洲va久久久噜噜噜久久狠狠 | 亚洲国产成人爱av在线播放| 国产肉丝袜在线观看| 国产真人性做爰久久网站| 新狼窝色av性久久久久久| 久久香综合精品久久伊人| 四虎精品国产永久在线观看| 久久久一本精品99久久精品88| 亂倫近親相姦中文字幕| 亚洲伊人久久大香线蕉综合图片 | 亚洲伦无码中文字幕另类| 久久婷婷五月综合97色| 亚洲熟妇av日韩熟妇在线| 性色欲情网站| 一級特黃色毛片免費看| 国产精品三级一区二区| 好男人社区神马在线观看www| 亚洲a∨精品永久无码| 国产亚洲精品a在线观看下载| 九九久久精品国产av片国产| 亚洲国产av玩弄放荡人妇系列| 国产午夜免费高清久久影院| 大胸美女被吃奶爽死视频| 日韩综合夜夜香内射| 最新亚洲精品国偷自产在线| 日韩在线成年视频人网站观看| 麻豆高清免费国产一区 | 国产成人av国语在线观看| 欧美写真视频在线观看| 乱女伦露脸对白在线播放|