在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ras-related protein Rab-9A (RAB9A)

Recombinant Human Ras-related protein Rab-9A (RAB9A)

  • 中文名稱：
    人RAB9A重組蛋白
  • 貨號：
    CSB-YP019224HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人RAB9A重組蛋白
  • 貨號：
    CSB-EP019224HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人RAB9A重組蛋白
  • 貨號：
    CSB-EP019224HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人RAB9A重組蛋白
  • 貨號：
    CSB-BP019224HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人RAB9A重組蛋白
  • 貨號：
    CSB-MP019224HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RAB9A
  • Uniprot No.：
  • 別名：
    2410064E05Rik; AI195561; DmRab9; Rab 9; RAB 9A; RAB9 member RAS oncogene family; RAB9A; RAB9A member RAS oncogene family; RAB9A_HUMAN; RAS ASSOCIATED PROTEIN RAB9; Ras related protein Rab 9A; Ras-related protein Rab-9A; Sid6061p; Sid99
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-201
  • 氨基酸序列
    AGKSSLFKV ILLGDGGVGK SSLMNRYVTN KFDTQLFHTI GVEFLNKDLE VDGHFVTMQI WDTAGQERFR SLRTPFYRGS DCCLLTFSVD DSQSFQNLSN WKKEFIYYAD VKEPESFPFV ILGNKIDISE RQVSTEEAQA WCRDNGDYPY FETSAKDATN VAAAFEEAVR RVLATEDRSD HLIQTDTVNL HRKPKPSSSC C
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
  • 基因功能參考文獻：
    1. RAB9 competes with the catalytic subunit PPP2CA in binding to PPP2R1A. This competitive association has an important role in controlling the PP2A catalytic activity. PMID: 27611305
    2. protein kinase C modulates alpha1B-adrenergic receptor transfer to late endosomes and that Rab9 regulates this process and participates in G protein-mediated signaling turn-off. PMID: 28082304
    3. Rab9A and its co-regulatory GTPases control STX13-mediated cargo delivery to maturing melanosomes. PMID: 26527546
    4. Rab9-complexed TIP47 plays an essential role for the proper release of hepatitis C viral particles. PMID: 24480419
    5. Rab9a and Rab7b are mediators of the transit of the L2 capsid protien and the pseudogenome of human papillomavirus 16 from the late endosome to the golgi complex. PMID: 23345514
    6. Rab9A and Rab23 GTPases play crucial roles in autophagy of Group A Streptococcus. PMID: 22452336
    7. These data show that RUTBC2 can act as a Rab36 GAP in cells and suggest that RUTBC2 links Rab9A function to Rab36 function in the endosomal system. PMID: 22637480
    8. RUTBC1 is a Tre2/Bub2/Cdc16 domain-containing protein that binds to Rab9A-GTP both in vitro and in cultured cells, but is not a GTPase-activating protein for Rab9A. PMID: 21808068
    9. Data show that recombinant HPS1-HPS4 produced in insect cells can be efficiently isolated as a 1:1 heterodimer, and might function as a Rab9 effector in the biogenesis of lysosome-related organelles. PMID: 20048159
    10. Data show that ectopic expression of human telomerase reverse transcriptase (hTeRT) in human cells leads to an upregulation of the small GTPase Rab9 and its effector p40. PMID: 12576506
    11. The overall structure shows a characteristic nucleotide binding fold consisting of a six-stranded beta-sheet surrounded by five alpha-helices with a tightly bound GDP molecule in the active site. PMID: 15263003
    12. cholesterol contributes directly to the sequestration of Rab9 on Niemann-Pick type C cell membranes, which in turn, disrupts mannose 6-phosphate receptor trafficking PMID: 16644737
    13. Binding of the effector protein TIP47 is important for Rab9 localization. PMID: 16769818
    14. Rab9 interacts with the intermediate filament vimentin. This interaction is altered by lipid accumulation in late endosomes, which results in inhibition of protein kinase C and hypophosphorylation of vimentin, leading to late endosome dysfunction. PMID: 18681838
    15. VV p37 protein associates with host TIP47, Rab9 and CI-MPR. PMID: 19400954
    16. Data indicate that human copper transporter 1 cleavage occurs in a late endosomal, Rab9-positive compartment prior to delivery of the transporter to the plasma membrane. PMID: 19684018

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Melanosome.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數據庫鏈接：

    HGNC: 9792

    OMIM: 300284

    KEGG: hsa:9367

    STRING: 9606.ENSP00000420127

    UniGene: Hs.495704



主站蜘蛛池模板： 亚洲欧美日韩成人一区二区三区 | 无码人妻一区二区三区一| 国产真实夫妇交换视频| 99热国产这里只有精品9| 色偷偷偷久久伊人大杳蕉| 国产性色αv视频免费| 大地资源网第二页免费观看| 日日狠狠久久8888偷偷色| 国产aⅴ精品一区二区三区尤物| 久久无码喷吹高潮播放不卡| 精品亚洲欧美无人区乱码| 国产剧情国产精品一区| 久久一本久综合久久爱| 亚洲人成电影在线天堂色| 老师粉嫩小泬喷水视频90| 无码av一区二区三区无码| 精品视频一区二区三区在线观看| 国产av无码专区亚洲草草| 亚洲精品午夜一区二区电影院| 精品综合久久久久久98| 少妇被粗大的猛烈进出免费视频| 精品国内自产拍在线播放观看| 日韩人妻不卡一区二区三区| 亚洲精品中文字幕| 国产午夜福利在线观看视频| 99久久久无码国产精品试看| 亚洲精品无码成人aaa片| 久久综合av免费观看| 激情久久av一区av二区av三区| 亚洲欧洲av综合色无码| 人禽交 欧美 网站| 久久国产精品无码网站| 亚洲熟熟妇xxxx| 国产成人卡2卡3卡4乱码| 亚洲区激情区无码区日韩区| 欧美丰满熟妇xx猛交| 亚洲国产成人av人片久久| 天天摸天天摸天天天天看| 国精产品一区一区三区有限公司 | 国产精品无码免费专区午夜| 免费看无码自慰一区二区|