在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RAB9A Antibody

  • 中文名稱:
    RAB9A兔多克隆抗體
  • 貨號:
    CSB-PA019224DSR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: RAB9A antibody at 7.66µg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: K562 whole cell lysate
      Lane 3: HepG2 whole cell lysate
      Lane 4: 293T whole cell lysate
      Lane 5: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 23 kDa
      Observed band size: 23 kDa
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA019224DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA019224DSR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RAB9A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RAB9A
  • 別名:
    2410064E05Rik antibody; AI195561 antibody; DmRab9 antibody; Rab 9 antibody; RAB 9A antibody; RAB9 member RAS oncogene family antibody; RAB9A antibody; RAB9A member RAS oncogene family antibody; RAB9A_HUMAN antibody; RAS ASSOCIATED PROTEIN RAB9 antibody; Ras related protein Rab 9A antibody; Ras-related protein Rab-9A antibody; Sid6061p antibody; Sid99 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ras-related protein Rab-9A protein (122-201AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
  • 基因功能參考文獻:
    1. RAB9 competes with the catalytic subunit PPP2CA in binding to PPP2R1A. This competitive association has an important role in controlling the PP2A catalytic activity. PMID: 27611305
    2. protein kinase C modulates alpha1B-adrenergic receptor transfer to late endosomes and that Rab9 regulates this process and participates in G protein-mediated signaling turn-off. PMID: 28082304
    3. Rab9A and its co-regulatory GTPases control STX13-mediated cargo delivery to maturing melanosomes. PMID: 26527546
    4. Rab9-complexed TIP47 plays an essential role for the proper release of hepatitis C viral particles. PMID: 24480419
    5. Rab9a and Rab7b are mediators of the transit of the L2 capsid protien and the pseudogenome of human papillomavirus 16 from the late endosome to the golgi complex. PMID: 23345514
    6. Rab9A and Rab23 GTPases play crucial roles in autophagy of Group A Streptococcus. PMID: 22452336
    7. These data show that RUTBC2 can act as a Rab36 GAP in cells and suggest that RUTBC2 links Rab9A function to Rab36 function in the endosomal system. PMID: 22637480
    8. RUTBC1 is a Tre2/Bub2/Cdc16 domain-containing protein that binds to Rab9A-GTP both in vitro and in cultured cells, but is not a GTPase-activating protein for Rab9A. PMID: 21808068
    9. Data show that recombinant HPS1-HPS4 produced in insect cells can be efficiently isolated as a 1:1 heterodimer, and might function as a Rab9 effector in the biogenesis of lysosome-related organelles. PMID: 20048159
    10. Data show that ectopic expression of human telomerase reverse transcriptase (hTeRT) in human cells leads to an upregulation of the small GTPase Rab9 and its effector p40. PMID: 12576506
    11. The overall structure shows a characteristic nucleotide binding fold consisting of a six-stranded beta-sheet surrounded by five alpha-helices with a tightly bound GDP molecule in the active site. PMID: 15263003
    12. cholesterol contributes directly to the sequestration of Rab9 on Niemann-Pick type C cell membranes, which in turn, disrupts mannose 6-phosphate receptor trafficking PMID: 16644737
    13. Binding of the effector protein TIP47 is important for Rab9 localization. PMID: 16769818
    14. Rab9 interacts with the intermediate filament vimentin. This interaction is altered by lipid accumulation in late endosomes, which results in inhibition of protein kinase C and hypophosphorylation of vimentin, leading to late endosome dysfunction. PMID: 18681838
    15. VV p37 protein associates with host TIP47, Rab9 and CI-MPR. PMID: 19400954
    16. Data indicate that human copper transporter 1 cleavage occurs in a late endosomal, Rab9-positive compartment prior to delivery of the transporter to the plasma membrane. PMID: 19684018

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Melanosome.
  • 蛋白家族:
    Small GTPase superfamily, Rab family
  • 數據庫鏈接:

    HGNC: 9792

    OMIM: 300284

    KEGG: hsa:9367

    STRING: 9606.ENSP00000420127

    UniGene: Hs.495704



主站蜘蛛池模板: 永久免费观看的毛片手机视频| 久久精品水蜜桃av综合天堂| 精品亚洲成a人在线观看| 午夜福利理论片在线观看播放| 国产精品无码av一区二区三区| 免费人成网站在线观看不卡| 国产免费内射又粗又爽密桃视频| 国产成人精品2021| 久久伊99综合婷婷久久伊| 国产一卡二卡三新区2022| 99久久人妻精品免费一区| 性色做爰片在线观看ww| 国产精品一国产精品| 日本一卡2卡三卡4卡免费网站| 99国产欧美久久久精品| 理论片午午伦夜理片影院99| 免费萌白酱国产一区二区三区| 亚洲精品无码av专区最新| 国产精品久久久亚洲| 欧美黑人巨大videos在线| 亚洲色播永久网址大全| 久久综合久色欧美综合狠狠| 免费无码av片在线观看播放| 中文字幕亚洲精品乱码| 中文天堂最新版资源www官网| 久久成人国产精品| 久久午夜福利无码1000合集| 午夜福利麻豆国产精品| 国产成人亚洲综合图区| 免费看一区二区三区四区| ass日本丰满熟妇pics| 成在人线av无码免观看午夜网| 中文字幕乱码人在线视频1区| 天天槽夜夜槽槽不停| 少妇伦子伦精品无吗| 男人扒女人添高潮视频| 亚洲色大网站www永久网站| 欧洲女人性开放免费网站| 无码一区二区三区久久精品| 国产色无码精品视频国产| 丁香五月缴情在线|