在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RAB9A Antibody

  • 中文名稱:
    RAB9A兔多克隆抗體
  • 貨號:
    CSB-PA172973
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA172973(RAB9A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA172973(RAB9A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, hepg2 cells, RAW264.7 cells, NIH/3T3 cells, Primary antibody: CSB-PA172973(RAB9A Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    RAB9A
  • 別名:
    2410064E05Rik antibody; AI195561 antibody; DmRab9 antibody; Rab 9 antibody; RAB 9A antibody; RAB9 member RAS oncogene family antibody; RAB9A antibody; RAB9A member RAS oncogene family antibody; RAB9A_HUMAN antibody; RAS ASSOCIATED PROTEIN RAB9 antibody; Ras related protein Rab 9A antibody; Ras-related protein Rab-9A antibody; Sid6061p antibody; Sid99 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human RAB9A
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
  • 基因功能參考文獻:
    1. RAB9 competes with the catalytic subunit PPP2CA in binding to PPP2R1A. This competitive association has an important role in controlling the PP2A catalytic activity. PMID: 27611305
    2. protein kinase C modulates alpha1B-adrenergic receptor transfer to late endosomes and that Rab9 regulates this process and participates in G protein-mediated signaling turn-off. PMID: 28082304
    3. Rab9A and its co-regulatory GTPases control STX13-mediated cargo delivery to maturing melanosomes. PMID: 26527546
    4. Rab9-complexed TIP47 plays an essential role for the proper release of hepatitis C viral particles. PMID: 24480419
    5. Rab9a and Rab7b are mediators of the transit of the L2 capsid protien and the pseudogenome of human papillomavirus 16 from the late endosome to the golgi complex. PMID: 23345514
    6. Rab9A and Rab23 GTPases play crucial roles in autophagy of Group A Streptococcus. PMID: 22452336
    7. These data show that RUTBC2 can act as a Rab36 GAP in cells and suggest that RUTBC2 links Rab9A function to Rab36 function in the endosomal system. PMID: 22637480
    8. RUTBC1 is a Tre2/Bub2/Cdc16 domain-containing protein that binds to Rab9A-GTP both in vitro and in cultured cells, but is not a GTPase-activating protein for Rab9A. PMID: 21808068
    9. Data show that recombinant HPS1-HPS4 produced in insect cells can be efficiently isolated as a 1:1 heterodimer, and might function as a Rab9 effector in the biogenesis of lysosome-related organelles. PMID: 20048159
    10. Data show that ectopic expression of human telomerase reverse transcriptase (hTeRT) in human cells leads to an upregulation of the small GTPase Rab9 and its effector p40. PMID: 12576506
    11. The overall structure shows a characteristic nucleotide binding fold consisting of a six-stranded beta-sheet surrounded by five alpha-helices with a tightly bound GDP molecule in the active site. PMID: 15263003
    12. cholesterol contributes directly to the sequestration of Rab9 on Niemann-Pick type C cell membranes, which in turn, disrupts mannose 6-phosphate receptor trafficking PMID: 16644737
    13. Binding of the effector protein TIP47 is important for Rab9 localization. PMID: 16769818
    14. Rab9 interacts with the intermediate filament vimentin. This interaction is altered by lipid accumulation in late endosomes, which results in inhibition of protein kinase C and hypophosphorylation of vimentin, leading to late endosome dysfunction. PMID: 18681838
    15. VV p37 protein associates with host TIP47, Rab9 and CI-MPR. PMID: 19400954
    16. Data indicate that human copper transporter 1 cleavage occurs in a late endosomal, Rab9-positive compartment prior to delivery of the transporter to the plasma membrane. PMID: 19684018

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Melanosome.
  • 蛋白家族:
    Small GTPase superfamily, Rab family
  • 數據庫鏈接:

    HGNC: 9792

    OMIM: 300284

    KEGG: hsa:9367

    STRING: 9606.ENSP00000420127

    UniGene: Hs.495704



主站蜘蛛池模板: 影音先锋无码aⅴ男人资源站| 色欲天天婬色婬香视频综合网| 天天狠天天添日日拍| 色噜噜一区二区三区| 欧美性猛交xxxx乱大交极品| 少妇高潮太爽了在线视| 久久精品青青草原伊人| 日本公妇乱偷中文字幕| 国产成人精品男人的天堂| 国产午夜亚洲精品久久 | 99大香伊乱码一区二区| 丝袜 亚洲 另类 欧美 变态 | 特级毛片爽www免费版| 国产av一区二区三区天堂综合网| 亚洲国产综合在线观看不卡| av电影在线观看| 免费中文字幕日韩欧美| 国精产品999一区二区三区有限| 午夜国产成人片在线播放| 在线视频观看免费视频18| 欧美一区二区| 2021久久精品国产99国产精品| 中文字幕人妻偷伦在线视频| 久久精品中文字幕一区| 狠狠干狠狠爱| 欧美人与动zozo在线播放| 国产香蕉尹人在线观看视频| 97色伦图片97综合影院 | 亚洲欧洲精品成人久久曰影片| 精品国产乱码久久久久久1区2区| 亚洲和欧洲一码二码区别7777| 色欲av蜜桃一区二区三| 精产一二三产区m553| 国产精品1区2区3区在线观看| 国产a线视频播放| 加勒比色综合久久久久久久久| 亚洲国产成人综合精品| 亚洲另类欧美综合在线 | 一本一道久久综合久久| 奶头好大狂揉60分钟视频| 波多野结衣av无码|