在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ras-related protein Rab-43 (RAB43)

Recombinant Human Ras-related protein Rab-43 (RAB43)

  • 中文名稱：
    人RAB43重組蛋白
  • 貨號：
    CSB-YP773063HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人RAB43重組蛋白
  • 貨號：
    CSB-EP773063HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人RAB43重組蛋白
  • 貨號：
    CSB-EP773063HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人RAB43重組蛋白
  • 貨號：
    CSB-BP773063HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人RAB43重組蛋白
  • 貨號：
    CSB-MP773063HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RAB43
  • Uniprot No.：
  • 別名：
    RAB41; RAB43; RAB43_HUMAN; Ras related protein Rab 41 ; Ras related protein Rab 43; Ras-related protein Rab-41; Ras-related protein Rab-43
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-212
  • 氨基酸序列
    MAGPGPGPGD PDEQYDFLFK LVLVGDASVG KTCVVQRFKT GAFSERQGST IGVDFTMKTL EIQGKRVKLQ IWDTAGQERF RTITQSYYRS ANGAILAYDI TKRSSFLSVP HWIEDVRKYA GSNIVQLLIG NKSDLSELRE VSLAEAQSLA EHYDILCAIE TSAKDSSNVE EAFLRVATEL IMRHGGPLFS EKSPDHIQLN SKDIGEGWGC GC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
  • 基因功能參考文獻：
    1. vesicle-associated RhoB is a regulator of the Rab11-mediated recycling of LFA-1 to the cell surface, an event that is necessary for T lymphocyte motility. PMID: 29233918
    2. Rab43 directly interacts with GPCRs and controls the forward ER-to-Golgi traffic of nascent GPCRs. PMID: 29069590
    3. High RAB43 expression is associated with epithelial-mesenchymal transition in gliomas. PMID: 28075478
    4. several crystal structures of the myosin Va or the myosin Vb globular tail domain that gives insights into how the motor is linked to the recycling membrane compartments via Rab11 or the melanophilin adaptor that binds to Rab27a. PMID: 24248336
    5. Data indicate taht the parasitophorous vacuole (PV), marked with Rab14, Rab30, or Rab43, colocalize with host-derived sphingolipids in the vacuolar space. PMID: 23615442
    6. SGK1,3 enhances the expression level of mature hERG channels by inhibiting Nedd4-2 as well as by promoting Rab11-mediated hERG recycling. PMID: 23589291
    7. Rab1a/b and Rab43, are important for herpes simplex virus 1 virion assembly PMID: 21680502
    8. The results of PCR amplification indicated that human RAB41 is widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver. PMID: 15018353
    9. Rab43 is the target of RN-tre and is required for Shiga toxin uptake. PMID: 17562788
    10. Results indicate that Rab1 and Rab43 are key Rabs required for the biogenesis and maintenance of a functional Golgi structure, and suggest that other Rabs acting at the Golgi complex are likely to be functionally redundant. PMID: 17684057
    11. Rab18 and Rab43 have key roles in ER-Golgi trafficking. PMID: 18664496

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver.
  • 數據庫鏈接：

    HGNC: 19983

    KEGG: hsa:339122

    STRING: 9606.ENSP00000319781

    UniGene: Hs.381132



主站蜘蛛池模板： 成人精品一区二区三区在线观看 | 中出人妻中文字幕无码| 特级做a爰片毛片免费看108| 老色鬼永久视频网站| 黑人巨大videos精品| 亚洲午夜精品a片一区二区app| 欧美交换国产一区内射| 国产韩国精品一区二区三区久久| 亚洲国产成人久久综合下载| 亚洲国产成人久久一区久久| 亚洲精品久久久久久中文| 粉嫩少妇内射浓精videos| 日本边添边摸边做边爱喷水| 亚洲偷精品国产五月丁香麻豆| 少妇与子乱毛片| 欧美国产成人精品一区二区三区 | 亚洲综合小说另类图片五月天| 亚洲成av 人片在线观看无码 | 成年美女黄网站色大免费视频| 熟女俱乐部五十路六十路av| 女人高潮抽搐潮喷小视频| 无码毛片一区二区本码视频| 性高湖久久久久久久久aaaaa| 日日摸日日添日日碰9学生露脸| 国产免费午夜福利在线播放11| 国产在线视频主播区| 亚洲 另类 熟女 字幕| 亚洲精品国产嫩草在线观看东京热 | 男女啪啪激烈高潮喷出gif免费| 肥老熟妇伦子伦456视频| 国产色视频自在线观看| 亚洲精品一区二区精华液| 北条麻妃在线一区二区| 免费观看又色又爽又黄的崩锅 | 九九热爱视频精品视频16| 久久久精品日本一区二区三区| 无尺码精品产品视频| 国产精成a品人v在线播放 | 国产亚洲精品久久久ai换脸| 无码人妻一区二区三区免费手机| (无码视频)在线观看|