在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB43 Antibody

RAB43 Antibody

  • 中文名稱：
    RAB43兔多克隆抗體
  • 貨號(hào)：
    CSB-PA019209GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RAB43
  • 別名：
    RAB41 antibody; RAB43 antibody; RAB43_HUMAN antibody; Ras related protein Rab 41 antibody; Ras related protein Rab 43 antibody; Ras-related protein Rab-41 antibody; Ras-related protein Rab-43 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RAB43
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
  • 基因功能參考文獻(xiàn)：
    1. vesicle-associated RhoB is a regulator of the Rab11-mediated recycling of LFA-1 to the cell surface, an event that is necessary for T lymphocyte motility. PMID: 29233918
    2. Rab43 directly interacts with GPCRs and controls the forward ER-to-Golgi traffic of nascent GPCRs. PMID: 29069590
    3. High RAB43 expression is associated with epithelial-mesenchymal transition in gliomas. PMID: 28075478
    4. several crystal structures of the myosin Va or the myosin Vb globular tail domain that gives insights into how the motor is linked to the recycling membrane compartments via Rab11 or the melanophilin adaptor that binds to Rab27a. PMID: 24248336
    5. Data indicate taht the parasitophorous vacuole (PV), marked with Rab14, Rab30, or Rab43, colocalize with host-derived sphingolipids in the vacuolar space. PMID: 23615442
    6. SGK1,3 enhances the expression level of mature hERG channels by inhibiting Nedd4-2 as well as by promoting Rab11-mediated hERG recycling. PMID: 23589291
    7. Rab1a/b and Rab43, are important for herpes simplex virus 1 virion assembly PMID: 21680502
    8. The results of PCR amplification indicated that human RAB41 is widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver. PMID: 15018353
    9. Rab43 is the target of RN-tre and is required for Shiga toxin uptake. PMID: 17562788
    10. Results indicate that Rab1 and Rab43 are key Rabs required for the biogenesis and maintenance of a functional Golgi structure, and suggest that other Rabs acting at the Golgi complex are likely to be functionally redundant. PMID: 17684057
    11. Rab18 and Rab43 have key roles in ER-Golgi trafficking. PMID: 18664496

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19983

    KEGG: hsa:339122

    STRING: 9606.ENSP00000319781

    UniGene: Hs.381132



主站蜘蛛池模板： 99久久久无码国产精品动漫| 无码高潮爽到爆的喷水视频| 国产精品美女一区二区视频| 久久久久青草线综合超碰| 亚洲精品无码成人aaa片| 丰满多毛少妇做爰视频爽爽和| 色妺妺视频网| 欧美性插b在线视频网站| 国产亚洲产品影视在线产品| 无码人妻在线一区二区三区免费| 一本大道东京热无码| 最近中文字幕mv在线资源 | 爱色精品视频一区二区| 婷婷色婷婷开心五月四房播播久久| 文中字幕一区二区三区视频播放| 伊人久久大香线蕉av一区二区| 午夜男女无遮挡拍拍视频| 日本乱码一区二区三区不卡| www夜插内射视频网站| 内射少妇36p亚洲区| 国精品人妻无码一区免费视频电影 | 国产天堂亚洲国产碰碰| 亚洲精品蜜桃久久久久久| 免费无人区男男码卡二卡| 亚洲嫩模喷白浆在线观看| 西欧free性满足hd老熟妇| 18禁黄无遮挡网站免费| 一本色道久久综合狠狠躁篇| 超碰aⅴ人人做人人爽欧美| 少妇被粗大的猛烈进出免费视频| 午夜伦4480yy私人影院| 欧美巨大黑人精品videos| 在线a亚洲视频播放在线观看| 欧美三级不卡在线播放| 日韩国产亚洲高清在线久草| 亚洲精品无码国产片| 亚洲深深色噜噜狠狠爱网站| 精品国产av一区二区果冻传媒| 亚洲国产精品va在线看黑人| 乱子轮熟睡1区| 2021国产精品香蕉在线观看|