在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein tyrosine phosphatase type IVA 2 (PTP4A2)

  • 中文名稱:
    人PTP4A2重組蛋白
  • 貨號:
    CSB-YP613277HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PTP4A2重組蛋白
  • 貨號:
    CSB-EP613277HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PTP4A2重組蛋白
  • 貨號:
    CSB-EP613277HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PTP4A2重組蛋白
  • 貨號:
    CSB-BP613277HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PTP4A2重組蛋白
  • 貨號:
    CSB-MP613277HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PTP4A2
  • Uniprot No.:
  • 別名:
    PTP4A2; PRL2; PTPCAAX2; BM-008; Protein tyrosine phosphatase type IVA 2; EC 3.1.3.48; HU-PP-1; OV-1; PTP(CAAXII); Protein-tyrosine phosphatase 4a2; Protein-tyrosine phosphatase of regenerating liver 2; PRL-2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-164
  • 氨基酸序列
    MNRPAPVEIS YENMRFLITH NPTNATLNKF TEELKKYGVT TLVRVCDATY DKAPVEKEGI HVLDWPFDDG APPPNQIVDD WLNLLKTKFR EEPGCCVAVH CVAGLGRAPV LVALALIECG MKYEDAVQFI RQKRRGAFNS KQLLYLEKYR PKMRLRFRDT NGHC
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
  • 基因功能參考文獻:
    1. identified a critical role for PRL2 phosphatase in the proliferation and survival of human AML cells. Further, we demonstrated that PRL2 is essential for the leukemogenic potential of AML1-ETO9a in vivo PMID: 28220038
    2. Our findings highlight the important role of miR-29c in regulating CRC EMT via GSK-3b/b-catenin signaling by targeting GNA13 and PTP4A and provide new insights into the metastatic basis of colorectal cancer PMID: 25193986
    3. PTP4A2 expression is correlated with overall survival in progestin receptor-positive breast carcinomas. PMID: 23568563
    4. Results suggest a model in which PRL-2 promotes cell migration and invasion through an ERK1/2-dependent signaling pathway. PMID: 21765462
    5. PRL-2 plays an important role in lung cancer and can be a biomarker of lung cancer, substituting for the function of other PRLs. PMID: 21993571
    6. Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression. PMID: 20841483
    7. Mouse pre-B-cells transfected with human PRL-2 had higher growth responses to Epo or IL-3, shorter cell cycle, less Epo requirement for survival, more cell migration, less cell adhesion, change to an immature cell morphology, & more Bmi-1 expression. PMID: 20226699
    8. PRL-2 can promote cell adhesion and invasion activity of human hepatocellular carcinoma cells. PMID: 17666324
    9. PRL-2 mRNA expression was not significantly higher in malignant compared to benign breast tissue. PMID: 16832410
    10. PRL-2 was expressed heavily in almost every tissue and cell type examined. Widespread expression of PRL-2 in multiple organ systems suggests an important functional role for these enzymes in normal tissue homeostasis. PMID: 16957164

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane. Early endosome. Cytoplasm.
  • 蛋白家族:
    Protein-tyrosine phosphatase family
  • 組織特異性:
    Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
  • 數據庫鏈接:

    HGNC: 9635

    OMIM: 601584

    KEGG: hsa:8073

    STRING: 9606.ENSP00000344909

    UniGene: Hs.470477



主站蜘蛛池模板: 插一插射一射视频| 国产精品白丝久久av网站| 一本久久伊人热热精品中文字幕| 亚洲五月综合缴情在线观看| 国产亚洲曝欧美不卡精品| 亚洲成a人v欧美综合天堂麻豆| 国产无遮挡又黄又爽又色| 亚洲精品欧美综合四区| 东北老女人高潮大喊舒服死了| 欧美人禽zozo动人物杂交| 免费无码一区二区三区a片百度 | 午夜尤物禁止18点击进入| 亚洲乱码卡一卡二卡新区仙踪木木 | 国产一区二区三区乱码| 欧美性videos高清精品| 欧美老妇牲交videos| 日本午夜精品一区二区三区电影| 久久视热这里只有精品| 蜜臀av无码精品人妻色欲| 爱性久久久久久久久| 日本熟妇人妻xxxxx-欢迎您| 婷婷网色偷偷亚洲男人甘肃| 色婷婷综合久久久中文字幕| 国产成a人亚洲精v品无码| 亚洲国产精品嫩草影院永久 | 久久精品免费国产大片| 国产精品女主播在线视频| 国产高清自产拍av在线| 少妇伦子伦情品无吗| 老司机久久99久久精品播放| 伊伊人成亚洲综合人网| 妺妺窝人体色www在线观看| 日本三级欧美三级人妇视频黑白配 | 中文字幕日本乱码仑区在线| 欧美性大战久久久久xxx| 中文字幕在线观看亚洲视频| 亚洲香蕉网久久综合影视| av在线播放日韩亚洲欧我不卡| 亚洲中文字幕一区精品自拍| 国产人妻精品一区二区三区| 亚洲国产天堂久久久久久|