在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTP4A2 Antibody, FITC conjugated

  • 中文名稱:
    PTP4A2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA613277LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTP4A2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PTP4A2
  • 別名:
    PTP4A2 antibody; PRL2 antibody; PTPCAAX2 antibody; BM-008 antibody; Protein tyrosine phosphatase type IVA 2 antibody; EC 3.1.3.48 antibody; HU-PP-1 antibody; OV-1 antibody; PTP(CAAXII) antibody; Protein-tyrosine phosphatase 4a2 antibody; Protein-tyrosine phosphatase of regenerating liver 2 antibody; PRL-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein tyrosine phosphatase type IVA 2 protein (1-164AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
  • 基因功能參考文獻:
    1. identified a critical role for PRL2 phosphatase in the proliferation and survival of human AML cells. Further, we demonstrated that PRL2 is essential for the leukemogenic potential of AML1-ETO9a in vivo PMID: 28220038
    2. Our findings highlight the important role of miR-29c in regulating CRC EMT via GSK-3b/b-catenin signaling by targeting GNA13 and PTP4A and provide new insights into the metastatic basis of colorectal cancer PMID: 25193986
    3. PTP4A2 expression is correlated with overall survival in progestin receptor-positive breast carcinomas. PMID: 23568563
    4. Results suggest a model in which PRL-2 promotes cell migration and invasion through an ERK1/2-dependent signaling pathway. PMID: 21765462
    5. PRL-2 plays an important role in lung cancer and can be a biomarker of lung cancer, substituting for the function of other PRLs. PMID: 21993571
    6. Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression. PMID: 20841483
    7. Mouse pre-B-cells transfected with human PRL-2 had higher growth responses to Epo or IL-3, shorter cell cycle, less Epo requirement for survival, more cell migration, less cell adhesion, change to an immature cell morphology, & more Bmi-1 expression. PMID: 20226699
    8. PRL-2 can promote cell adhesion and invasion activity of human hepatocellular carcinoma cells. PMID: 17666324
    9. PRL-2 mRNA expression was not significantly higher in malignant compared to benign breast tissue. PMID: 16832410
    10. PRL-2 was expressed heavily in almost every tissue and cell type examined. Widespread expression of PRL-2 in multiple organ systems suggests an important functional role for these enzymes in normal tissue homeostasis. PMID: 16957164

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane. Early endosome. Cytoplasm.
  • 蛋白家族:
    Protein-tyrosine phosphatase family
  • 組織特異性:
    Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
  • 數據庫鏈接:

    HGNC: 9635

    OMIM: 601584

    KEGG: hsa:8073

    STRING: 9606.ENSP00000344909

    UniGene: Hs.470477



主站蜘蛛池模板: 国产成人精品无码播放| 亚洲成成品网站源码中国有限公司| 亚洲精品久久久www小说 | 欧美性猛交xxxx乱大交3| а天堂中文官网| 久久精品农村毛片| 性xxxxx大片免费视频| 亚洲精品无码高潮喷水a片软| 国产无遮挡又黄又爽动态图| 人妻av无码专区| 久久免费的精品国产v∧| 亚洲高清乱码午夜电影网| 国产福利无码一区在线| 久久久久麻豆v国产精华液好用吗 99久久人妻精品免费一区 | 人妻无码一区二区三区免费| 日本午夜看x费免| 天天爽夜夜爽人人爽免费| 免费人成视频x8x8| 18禁黄无遮挡网站免费| 四虎精品国产永久在线观看| 久久国产乱子伦免费精品| 亚洲欧美国产精品久久久久久久| 老子午夜理论影院理论| 亚洲 欧美 动漫 少妇 自拍| 粗大的内捧猛烈进出| 欧美性猛交xxxx乱大交极品| 曰批免费视频播放免费直播| 国产卡1卡2卡3麻豆精品免费| 老熟女五十路乱子交尾中出一区 | 日本三级香港三级人妇三| 丰满人妻无码∧v区视频| 日本亚洲欧洲无免费码在线| 99久久久无码国产精品免费| 99精品国产福利在线观看| 在线成 人av影院| 国产精品国产三级国产专区53| 狠狠躁夜夜躁人人爽蜜桃| 中文字幕av无码人妻| 国产精品久久久久久亚洲色| 国产成人亚洲综合色婷婷| 学生妹无套内射正在播放|