在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTP4A2 Antibody, FITC conjugated

  • 中文名稱:
    PTP4A2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA613277LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTP4A2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PTP4A2
  • 別名:
    PTP4A2 antibody; PRL2 antibody; PTPCAAX2 antibody; BM-008 antibody; Protein tyrosine phosphatase type IVA 2 antibody; EC 3.1.3.48 antibody; HU-PP-1 antibody; OV-1 antibody; PTP(CAAXII) antibody; Protein-tyrosine phosphatase 4a2 antibody; Protein-tyrosine phosphatase of regenerating liver 2 antibody; PRL-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein tyrosine phosphatase type IVA 2 protein (1-164AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
  • 基因功能參考文獻:
    1. identified a critical role for PRL2 phosphatase in the proliferation and survival of human AML cells. Further, we demonstrated that PRL2 is essential for the leukemogenic potential of AML1-ETO9a in vivo PMID: 28220038
    2. Our findings highlight the important role of miR-29c in regulating CRC EMT via GSK-3b/b-catenin signaling by targeting GNA13 and PTP4A and provide new insights into the metastatic basis of colorectal cancer PMID: 25193986
    3. PTP4A2 expression is correlated with overall survival in progestin receptor-positive breast carcinomas. PMID: 23568563
    4. Results suggest a model in which PRL-2 promotes cell migration and invasion through an ERK1/2-dependent signaling pathway. PMID: 21765462
    5. PRL-2 plays an important role in lung cancer and can be a biomarker of lung cancer, substituting for the function of other PRLs. PMID: 21993571
    6. Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression. PMID: 20841483
    7. Mouse pre-B-cells transfected with human PRL-2 had higher growth responses to Epo or IL-3, shorter cell cycle, less Epo requirement for survival, more cell migration, less cell adhesion, change to an immature cell morphology, & more Bmi-1 expression. PMID: 20226699
    8. PRL-2 can promote cell adhesion and invasion activity of human hepatocellular carcinoma cells. PMID: 17666324
    9. PRL-2 mRNA expression was not significantly higher in malignant compared to benign breast tissue. PMID: 16832410
    10. PRL-2 was expressed heavily in almost every tissue and cell type examined. Widespread expression of PRL-2 in multiple organ systems suggests an important functional role for these enzymes in normal tissue homeostasis. PMID: 16957164

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane. Early endosome. Cytoplasm.
  • 蛋白家族:
    Protein-tyrosine phosphatase family
  • 組織特異性:
    Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
  • 數據庫鏈接:

    HGNC: 9635

    OMIM: 601584

    KEGG: hsa:8073

    STRING: 9606.ENSP00000344909

    UniGene: Hs.470477



主站蜘蛛池模板: 人妻无码一区二区三区| 欧美成 人 在线播放视频| 亚洲精品久久久口爆吞精| 国产成人综合久久亚洲精品| 国产亚洲无线码一区二区| 成人性欧美丨区二区三区| 免费无码又爽又刺激高潮的app | 欧洲无线码免费一区| 亚洲欧美日韩一区在线观看| 亚洲午夜爱爱香蕉片| 国精品人妻无码一区二区三区d3| 在线人成免费视频69国产| 日本一区午夜艳熟免费| 一本一道波多野结衣av一区| 国产成人综合亚洲色就色| 色六月婷婷亚洲婷婷六月| 人妻精品久久久久中文字幕69| 国产高清av首播原创麻豆| 欧洲美洲精品一区二区三区| 午夜免费啪在线观看视频| 一本大道东京热无码一区| 欧美猛少妇色xxxxx猛叫| 99久久免费国产精品| 免费床视频大全叫不停欧美| 少妇人妻偷人精品视蜜桃| 亚洲欧美日韩中文播放| 亚洲午夜精品a片一区二区app | 两个人看的www免费视频中文| 免费人妻精品一区二区三区| 国产成人精品视频网站| 亚洲午夜福利院在线观看| 少妇性饥渴无码a区免费| 丝袜无码专区人妻视频| av国産精品毛片一区二区视频| 婷婷丁香五月亚洲中文字幕| 国产 | 久你欧洲野花视频欧洲1| 真人性生交免费视频| 精品国产一区二区三区av色诱 | 国产精品卡1卡2卡三卡四| 影音先锋在线资源无码| 无码吃奶揉捏奶头高潮视频|