在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein-methionine sulfoxide oxidase MICAL2 (MICAL2), partial

  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-EP013808HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-EP013808HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-BP013808HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-MP013808HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Name:MICAL2 Synonyms:KIAA0750, MICAL2PV1, MICAL2PV2
  • Uniprot No.:
  • 別名:
    MICAL2; KIAA0750; MICAL2PV1; MICAL2PV2; [F-actin]-monooxygenase MICAL2; EC 1.14.13.225; Molecule interacting with CasL protein 2; MICAL-2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
  • 基因功能參考文獻(xiàn):
    1. Data suggest that MICAL2 protein might be an important regulator of epithelial to mesenchymal transition and therefore a promising target for anti-metastatic therapy. PMID: 26689989
    2. These data show that SRF/MRTF-A signaling is regulated by MICAL-2-dependent redox regulation of nuclear actin. PMID: 24440334
    3. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation PMID: 22331357
    4. MICAL2-PV is likely to be involved in cancer progression of prostate cancer and could be a candidate as a novel molecular marker and/or target for treatment of prostate cancers. PMID: 16675569
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Mical family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24693

    OMIM: 608881

    KEGG: hsa:9645

    STRING: 9606.ENSP00000256194

    UniGene: Hs.501928



主站蜘蛛池模板: 亚洲精品国偷自产在线99人热 | 欧美肥妇bwbwbwbxx| 国内女人喷潮完整视频| 中文字幕日韩精品一区二区三区 | 天天爽夜夜爽视频精品| 国产又粗又猛又爽又黄的视频在线观看动漫| 亚洲精品一区二区三区四区乱码| 亚洲综合无码久久精品综合| 亚洲国产高清在线一区二区三区| 亚洲中文无码永久免| 18禁又污又黄又爽的网站不卡| 亚洲爆乳无码专区| 色欲av无码一区二区三区| 亚洲大色堂人在线无码| 免费人成在线观看网站品爱网| 精品亚洲欧美无人区乱码| 久久zyz资源站无码中文动漫| 少妇内射兰兰久久| 蜜臀av色欲a片无人一区| 蜜臀av999无码精品国产专区| 无码成a毛片免费| www.-级毛片线天内射视视| 亚洲乱码卡一卡二卡| 国产日产高清欧美一区| 18禁男女爽爽爽午夜网站免费| 97影院理论午夜伦不卡| 极品无码国模国产在线观看| 欧美最猛黑人xxxxx猛交| 亚洲人成色7777在线观看| 人人做人人爽国产视| 四虎影库久免费视频| 欧美人妻一区二区三区| 国产亚洲高清国产拍精品| 黑人与人妻无码中字视频| 少妇爆乳无码专区| 波多野结衣av一区二区全免费观看| 少妇mm被擦出白浆液视频| 天堂中文在线最新版地址| 色欲av永久无码精品无码蜜桃| 狠狠精品久久久无码中文字幕| 欧美丰满美乳xxⅹ高潮www|