在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein-methionine sulfoxide oxidase MICAL2 (MICAL2), partial

  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-EP013808HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-EP013808HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-BP013808HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MICAL2重組蛋白
  • 貨號:
    CSB-MP013808HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Name:MICAL2 Synonyms:KIAA0750, MICAL2PV1, MICAL2PV2
  • Uniprot No.:
  • 別名:
    MICAL2; KIAA0750; MICAL2PV1; MICAL2PV2; [F-actin]-monooxygenase MICAL2; EC 1.14.13.225; Molecule interacting with CasL protein 2; MICAL-2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
  • 基因功能參考文獻(xiàn):
    1. Data suggest that MICAL2 protein might be an important regulator of epithelial to mesenchymal transition and therefore a promising target for anti-metastatic therapy. PMID: 26689989
    2. These data show that SRF/MRTF-A signaling is regulated by MICAL-2-dependent redox regulation of nuclear actin. PMID: 24440334
    3. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation PMID: 22331357
    4. MICAL2-PV is likely to be involved in cancer progression of prostate cancer and could be a candidate as a novel molecular marker and/or target for treatment of prostate cancers. PMID: 16675569
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Mical family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24693

    OMIM: 608881

    KEGG: hsa:9645

    STRING: 9606.ENSP00000256194

    UniGene: Hs.501928



主站蜘蛛池模板: 婷婷综合另类小说色区| 欧美三级在线播放线观看| 无码人妻av免费一区二区三区| 女人爽到高潮免费看视频 | 久久香港三级台湾三级播放| 伊人久久大香线蕉av综合| 亚洲日本乱码中文在线电影| 国产精品国产三级国快看| 亚洲日韩av一区二区三区四区| 欧美亚洲国产精品久久| 国内野外强奷在线视频| 午夜福制92视频| 日本又黄又爽gif动态图| 97精品国产一区二区三区| 777精品出轨人妻国产| 国内精品久久人妻无码网站| 中国真实偷乱视频| 亚洲国产av高清无码| 亚洲精品久久久久久动漫器材一区| 丝袜自慰一区二区三区| 国产高清一区二区三区直播| 拍真实国产伦偷精品| 国产农村妇女精品一二区| 国产精品国语对白露脸在线播放| 99久在线国内在线播放免费观看| 国产又色又爽又高潮免费| aaaaa少妇高潮大片| 最新精品露脸国产在线| 久久精品国产99久久久| 日韩成人极品在线内射3p蜜臀| 亚洲最大的成人网站| 久久精品国产男包| 亚洲裸男gv网站| 妺妺窝人体色www看美女| 中文字幕三级人妻无码视频| 人妻少妇无码中文幕久久| 国产成人免费一区二区三区| 国产精品香蕉在线观看| 亚洲色成人网站永久| 日韩视频 中文字幕 视频一区| 男女裸体影院高潮|