在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MICAL2 Antibody, Biotin conjugated

MICAL2 Antibody, Biotin conjugated

  • 中文名稱：
    MICAL2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA013808LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MICAL2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MICAL2
  • 別名：
    MICAL2 antibody; KIAA0750 antibody; MICAL2PV1 antibody; MICAL2PV2 antibody; [F-actin]-monooxygenase MICAL2 antibody; EC 1.14.13.225 antibody; Molecule interacting with CasL protein 2 antibody; MICAL-2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human [F-actin]-monooxygenase MICAL2 protein (1-495AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that MICAL2 protein might be an important regulator of epithelial to mesenchymal transition and therefore a promising target for anti-metastatic therapy. PMID: 26689989
    2. These data show that SRF/MRTF-A signaling is regulated by MICAL-2-dependent redox regulation of nuclear actin. PMID: 24440334
    3. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation PMID: 22331357
    4. MICAL2-PV is likely to be involved in cancer progression of prostate cancer and could be a candidate as a novel molecular marker and/or target for treatment of prostate cancers. PMID: 16675569
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Mical family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 24693

    OMIM: 608881

    KEGG: hsa:9645

    STRING: 9606.ENSP00000256194

    UniGene: Hs.501928



主站蜘蛛池模板： 国产丝袜视频一区二区三区| 日本一二三区视频在线| 天天躁日日躁狠狠躁2018| 美女扒开奶罩露出奶头视频网站 | 少妇的肉体aa片免费| 国产一区二区三区久久精品| 国自产拍偷拍精品啪啪模特| 日韩精品无码中文字幕一区二区 | 狠狠色噜噜狠狠狠狠7777米奇| 日本内射精品一区二区视频| 国产欧美成人xxx视频| 人妻熟女一区二区aⅴ水野朝阳| 少妇的渴望hd高清在线播放| 久久久久免费精品国产| 先锋影音最新色资源站| 无码人妻丰满熟妇啪啪7774| 中文字幕久精品免费视频| 亚洲va中文字幕无码一二三区| 中字幕视频在线永久在线观看免费| 免费又黄又爽1000禁片| 麻豆av字幕无码中文| 久久99精品网久久| 亚洲情综合五月天| 最爽无遮挡行房视频| 天天看片天天av免费观看 | 无码国产片观看| 精品久久久无码中文字幕天天| 全免费又大粗又黄又爽少妇片| 柠檬福利精品视频导航| 九九线精品视频在线观看| 久久久日韩精品一区二区三区| 欧美国产激情18| 国产成人卡2卡3卡4乱码| 精品国产成人高清在线观看| 欧美人与物videos另类| 一本色综合网久久| 国产又粗又猛又爽的视频a片| 欧美va久久久噜噜噜久久| 极品尤物一区二区三区| 首页 综合国产 亚洲 丝袜 | 风韵犹存丰满大屁股熟妇|