在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MICAL2 Antibody, Biotin conjugated

MICAL2 Antibody, Biotin conjugated

  • 中文名稱：
    MICAL2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA013808LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MICAL2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MICAL2
  • 別名：
    MICAL2 antibody; KIAA0750 antibody; MICAL2PV1 antibody; MICAL2PV2 antibody; [F-actin]-monooxygenase MICAL2 antibody; EC 1.14.13.225 antibody; Molecule interacting with CasL protein 2 antibody; MICAL-2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human [F-actin]-monooxygenase MICAL2 protein (1-495AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that MICAL2 protein might be an important regulator of epithelial to mesenchymal transition and therefore a promising target for anti-metastatic therapy. PMID: 26689989
    2. These data show that SRF/MRTF-A signaling is regulated by MICAL-2-dependent redox regulation of nuclear actin. PMID: 24440334
    3. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation PMID: 22331357
    4. MICAL2-PV is likely to be involved in cancer progression of prostate cancer and could be a candidate as a novel molecular marker and/or target for treatment of prostate cancers. PMID: 16675569
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Mical family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 24693

    OMIM: 608881

    KEGG: hsa:9645

    STRING: 9606.ENSP00000256194

    UniGene: Hs.501928



主站蜘蛛池模板： 人人爽久久涩噜噜噜av| 上司人妻互换中文字幕| 日韩欧美亚洲综合久久| 久久综合99re88久久爱| 亚洲 欧美 另类 制服 日韩| 精品久久久久久久国产潘金莲| 久久婷婷成人综合色综合| 免费无码国产v片在线观看| 亚洲婷婷六月的婷婷| 又黄又湿免费高清视频| 国产午夜精品免费一区二区三区| 92午夜福利少妇系列| 天堂中文在线最新版地址| 无码免费一区二区三区| 无码不卡av东京热毛片| 超碰香蕉人人网99精品| 亚洲精品无码久久毛片| 日韩~欧美一中文字幕| 日本三级吃奶头添泬无码苍井空| 性无码免费一区二区三区在线| 国产成人亚洲日韩欧美| 欧美 日韩版国产在线播放| 伊人色综合一区二区三区| 国产精品成人无码久久久| 日韩av第一页在线播放| 人人添人人澡人人澡人人人人| 巨大黑人极品videos精品| 男人a天堂手机在线版| 国内少妇偷人精品视频| 免费无码一区二区三区a片百度 | 国内精品综合久久久40p| 中文字幕欧美亚州视频免费 | 亚洲最大天堂无码精品区| 无码国模国产在线观看免费| 国产白丝精品爽爽久久久久久蜜臀| 国内精品久久久久av福利秒拍| 日本一本二本三区免费| 无码写真精品永久福利在线| 午夜福利免费0948视频| 无码福利日韩神码福利片| 中文字幕av高清片|