在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MICAL2 Antibody

MICAL2 Antibody

  • 中文名稱：
    MICAL2兔多克隆抗體
  • 貨號：
    CSB-PA013808LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA013808LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA013808LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MICAL2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MICAL2
  • 別名：
    MICAL2 antibody; KIAA0750 antibody; MICAL2PV1 antibody; MICAL2PV2 antibody; [F-actin]-monooxygenase MICAL2 antibody; EC 1.14.13.225 antibody; Molecule interacting with CasL protein 2 antibody; MICAL-2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human [F-actin]-monooxygenase MICAL2 protein (1-495AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，MICAL2 Antibody (CSB-PA013808LA01HU)，的標記方式是Non-conjugated。對于MICAL2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA013808LB01HU MICAL2 Antibody, HRP conjugated ELISA
    FITC CSB-PA013808LC01HU MICAL2 Antibody, FITC conjugated
    Biotin CSB-PA013808LD01HU MICAL2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
  • 基因功能參考文獻：
    1. Data suggest that MICAL2 protein might be an important regulator of epithelial to mesenchymal transition and therefore a promising target for anti-metastatic therapy. PMID: 26689989
    2. These data show that SRF/MRTF-A signaling is regulated by MICAL-2-dependent redox regulation of nuclear actin. PMID: 24440334
    3. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation PMID: 22331357
    4. MICAL2-PV is likely to be involved in cancer progression of prostate cancer and could be a candidate as a novel molecular marker and/or target for treatment of prostate cancers. PMID: 16675569
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Mical family
  • 數據庫鏈接：

    HGNC: 24693

    OMIM: 608881

    KEGG: hsa:9645

    STRING: 9606.ENSP00000256194

    UniGene: Hs.501928



主站蜘蛛池模板： 国产一区二区在线影院| 四虎永久在线精品免费网站| 精品国产av 无码一区二区三区| 人人妻人人妻人人片av| 日韩精品中文字幕无码一区| 亚洲熟少妇在线播放999| 2020国产激情视频在线观看| 欧美日韩中文国产一区发布| 无码欧精品亚洲日韩一区| 午夜美女裸体福利视频| 成人免费无码视频在线网站| 国产精品福利自产拍久久| 亚洲中文字幕无码一区在线| 国产福利男女xx00视频| 亚洲国产精品无码久久久蜜芽| 国产精品午夜小视频观看| 午夜精品国产精品大乳美女| 国产99久一区二区三区a片| 国产av亚洲aⅴ一区二区| 国产福利免费视频不卡| 国产精品内射后入合集| 无码国产欧美一区二区三区不卡| 一本无码中文字幕在线观| 性色av无码久久一区二区三区| 日韩中文字幕在线一区二区三区| 激情射精爆插热吻无码视频| 日本无码一区二区三区不卡免费| 情侣做性视频在线播放| 国产人与禽zoz0性伦| 国产最新精品自产在线观看| 欧美毛多水多肥妇| 成人综合伊人五月婷久久| 国产a三级久久精品| 亚洲精品国产高清在线观看| 国产精品毛多多水多| 性色av免费观看| 成人爽a毛片免费网站| 国内午夜熟妇又乱又伦| 蜜臀av在线播放一区二区三区| 精品久久久久久无码人妻蜜桃| 688欧美人禽杂交狂配|