在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein MIS12 homolog (MIS12)

  • 中文名稱:
    人MIS12重組蛋白
  • 貨號:
    CSB-YP875639HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MIS12重組蛋白
  • 貨號:
    CSB-EP875639HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MIS12重組蛋白
  • 貨號:
    CSB-BP875639HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MIS12重組蛋白
  • 貨號:
    CSB-MP875639HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MIS12
  • Uniprot No.:
  • 別名:
    MIS12; Protein MIS12 homolog
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-205
  • 氨基酸序列
    MSVDPMTYEA QFFGFTPQTC MLRIYIAFQD YLFEVMQAVE QVILKKLDGI PDCDISPVQI RKCTEKFLCF MKGHFDNLFS KMEQLFLQLI LRIPSNILLP EDKCKETPYS EEDFQHLQKE IEQLQEKYKT ELCTKQALLA ELEEQKIVQA KLKQTLTFFD ELHNVGRDHG TSDFRESLVS LVQNSRKLQN IRDNVEKESK RLKIS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. Essential for proper kinetochore microtubule attachments.
  • 基因功能參考文獻:
    1. Whereas CENP-C recruits a single MIS12:NDC80 complex, the authors show here that CENP-T binds one MIS12:NDC80 and two NDC80 complexes upon phosphorylation by the mitotic CDK1:Cyclin B complex at three distinct CENP-T sites. PMID: 28012276
    2. RWD-containing proteins interact with the Mis12 complex to shape KMN network topology, as revealed by structural analysis PMID: 24530301
    3. Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. PMID: 21353556
    4. These findings support a novel role for Hsp90-Sgt1 chaperones in ensuring the fidelity of Mis12 multiprotein complex assembly. PMID: 20404110
    5. hMIS12 has a role in mitosis and localizes at kinetochores PMID: 12515822
    6. These results indicate that a four-subunit Mis12 complex plays an essential role in chromosome segregation in vertebrates and contributes to mitotic kinetochore assembly. PMID: 16585270

    顯示更多

    收起更多

  • 亞細胞定位:
    Chromosome, centromere, kinetochore.
  • 蛋白家族:
    Mis12 family
  • 數據庫鏈接:

    HGNC: 24967

    OMIM: 609178

    KEGG: hsa:79003

    STRING: 9606.ENSP00000370557

    UniGene: Hs.267194



主站蜘蛛池模板: 亚洲伊人成无码综合影院| 九九视频国产免| 国产精品sm捆绑调教视频| 天天鲁在视频在线观看| 成人无码精品一区二区三区亚洲区| 国产一区二区不卡老阿姨| 无码av中文字幕免费放| 少妇大叫太大太爽受不了在线观看| 少妇被多人c夜夜爽爽| 爱做久久久久久| 麻豆国产精品va在线观看| 国产农村黄aaaaa特黄av毛片| 国产欧美日韩中文久久| 精品无码无人网站免费视频 | 鲁一鲁一鲁一鲁一曰综合网| 亚洲の无码国产の无码步美| 熟妇女人妻丰满少妇中文字幕| 国产色播av在线观看| 亚洲欧美在线观看品| 超碰免费公开| 国产肥熟女视频一区二区三区| 午夜好爽好舒服免费视频| 欧美 亚洲 日韩 中文2019| 日本高清视频在线www色| 偷看农村女人做爰毛片色| 久久成人国产精品无码 | 久久久亚洲精品一区二区三区| 欧美成人精品第一区二区三区| 伊人久久大香线蕉av波多野结衣| 99热网址最新获取域名| 制服丝袜中文字幕在线| 日本欧美久久久久免费播放网| 在线精品国精品国产尤物| 2020久热爱精品视频在线观看| 午夜天堂精品久久久久| 人妻无码一区二区三区tv| 99国产欧美久久久精品| 精品熟女日韩中文十区| 国产日韩精品欧美2020区| a欧美爰片久久毛片a片| 人妻无码中文久久久久专区|