在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Proteasome subunit beta type-7 (PSMB7)

  • 中文名稱:
    人PSMB7重組蛋白
  • 貨號:
    CSB-YP859509HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PSMB7重組蛋白
  • 貨號:
    CSB-EP859509HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PSMB7重組蛋白
  • 貨號:
    CSB-EP859509HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PSMB7重組蛋白
  • 貨號:
    CSB-BP859509HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PSMB7重組蛋白
  • 貨號:
    CSB-MP859509HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PSMB7
  • Uniprot No.:
  • 別名:
    Macropain chain Z; Multicatalytic endopeptidase complex chain Z; Proteasome (prosome macropain) subunit beta type 7; Proteasome beta 7 subunit; Proteasome catalytic subunit 2; Proteasome subunit alpha; Proteasome subunit beta 7 ; Proteasome subunit beta type-7; Proteasome subunit Z; PSB7_HUMAN; PSMB7; PUP1; Z
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    44-277
  • 氨基酸序列
    TTIAGVV YKDGIVLGAD TRATEGMVVA DKNCSKIHFI SPNIYCCGAG TAADTDMTTQ LISSNLELHS LSTGRLPRVV TANRMLKQML FRYQGYIGAA LVLGGVDVTG PHLYSIYPHG STDKLPYVTM GSGSLAAMAV FEDKFRPDME EEEAKNLVSE AIAAGIFNDL GSGSNIDLCV ISKNKLDFLR PYTVPNKKGT RLGRYRCEKG TTAVLTEKIT PLEIEVLEET VQTMDTS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
  • 基因功能參考文獻:
    1. Studied the associations of Protein Z (PROZ G79A) and Endothelin-1 (EDN1 G5665T) polymorphisms with the clinical features of sickle cell disease (SCD) in a cohort of Egyptian children with SCD. PMID: 28548215
    2. reduced protein levels in patients with rheumatoid arthritis in association with disease progression PMID: 21713324
    3. high PSMB7 expression is associated with anthracycline resistance in breast cancer. PMID: 20010949
    4. Low protein Z levels but not protein Z gene G79A polymorphism are a risk factor for ischemic stroke. PMID: 18378283
    5. A previously unreported sporadic missense mutation within exon 8 is described in a patient with very low protein Z levels. PMID: 18462727
    6. PSB7, PRDX1, and SRP9 up-regulation as candidate biomarkers of colon cancer is discovered PMID: 18549262
    7. ZPI functions like other serpins to regulate the activity of FXa but in a manner uniquely dependent on protein Z, procoagulant membranes, and pH PMID: 18768472
    8. we have identified and characterized a new phosphorylated isoform of the human 20S proteasome b7 subunit and showed its differential expression in tumor vs. normal cell lines PMID: 19645816

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Peptidase T1B family
  • 組織特異性:
    Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
  • 數據庫鏈接:

    HGNC: 9544

    OMIM: 604030

    KEGG: hsa:5695

    STRING: 9606.ENSP00000259457

    UniGene: Hs.213470



主站蜘蛛池模板: av无码人妻波多野结衣| 艳妇乳肉豪妇荡乳| 国产在线拍偷自揄拍无码| 亚洲韩国日本高清一区 | 免费无码久久成人网站入口| 国产欧美精品区一区二区三区| 窝窝午夜精品一区二区| 国产av精品毛片一区二区三区| 欧美精品a∨在线观看| 丰满熟妇人妻av无码区| 欧美精品久久久久久久自慰| 国产xxxx做受性欧美88| 欧美亚洲日本国产黑白配| 久久精品亚洲中文无东京热| 亚洲18禁私人影院| 日本道色综合久久影院| 久久国产免费福利永久| 国产又色又爽又刺激在线观看| 乌克兰少妇性做爰| 18处破外女出血在线| 无码a∨高潮抽搐流白浆| 少妇无码太爽了不卡视频在线看| 成人精品一区二区三区中文字幕| 久久精品国产999久久久 | 精品无码专区毛片| 一本本月无码-| 末发育女av片一区二区| 精选国产av精选一区二区三区| 艳妇乳肉豪妇荡乳av| 日本一二免费不卡区| 亚洲日韩一中文字暮av| 亚洲人成网站在线观看69影院| 十八岁污网站在线观看| 国产片a国产片免费看视频| 天堂网在线观看| 欧美黑人又粗又大高潮喷水| 亚洲伊人久久大香线蕉| 国产精成人品日日拍夜夜| а√在线中文网新版地址在线| 伊人色综合久久天天| 欧美精品1卡二卡三卡四卡|