在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PSMB7 Antibody

PSMB7 Antibody

  • 中文名稱：
    PSMB7兔多克隆抗體
  • 貨號：
    CSB-PA558008
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA558008(PSMB7 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA558008(PSMB7 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, hepG2 cells, human testis tissue, Human lung cancer tissue, Primary antibody: CSB-PA558008(PSMB7 Antibody) at dilution 1/310, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PSMB7
  • 別名：
    Macropain chain Z antibody; Multicatalytic endopeptidase complex chain Z antibody; Proteasome (prosome macropain) subunit beta type 7 antibody; Proteasome beta 7 subunit antibody; Proteasome catalytic subunit 2 antibody; Proteasome subunit alpha antibody; Proteasome subunit beta 7 antibody; Proteasome subunit beta type-7 antibody; Proteasome subunit Z antibody; PSB7_HUMAN antibody; PSMB7 antibody; PUP1 antibody; Z antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human PSMB7
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
  • 基因功能參考文獻：
    1. Studied the associations of Protein Z (PROZ G79A) and Endothelin-1 (EDN1 G5665T) polymorphisms with the clinical features of sickle cell disease (SCD) in a cohort of Egyptian children with SCD. PMID: 28548215
    2. reduced protein levels in patients with rheumatoid arthritis in association with disease progression PMID: 21713324
    3. high PSMB7 expression is associated with anthracycline resistance in breast cancer. PMID: 20010949
    4. Low protein Z levels but not protein Z gene G79A polymorphism are a risk factor for ischemic stroke. PMID: 18378283
    5. A previously unreported sporadic missense mutation within exon 8 is described in a patient with very low protein Z levels. PMID: 18462727
    6. PSB7, PRDX1, and SRP9 up-regulation as candidate biomarkers of colon cancer is discovered PMID: 18549262
    7. ZPI functions like other serpins to regulate the activity of FXa but in a manner uniquely dependent on protein Z, procoagulant membranes, and pH PMID: 18768472
    8. we have identified and characterized a new phosphorylated isoform of the human 20S proteasome b7 subunit and showed its differential expression in tumor vs. normal cell lines PMID: 19645816

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1B family
  • 組織特異性：
    Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
  • 數據庫鏈接：

    HGNC: 9544

    OMIM: 604030

    KEGG: hsa:5695

    STRING: 9606.ENSP00000259457

    UniGene: Hs.213470



主站蜘蛛池模板： 国产爆乳美女娇喘呻吟| 国产色诱视频在线播放网站| 国产成人愉拍精品| 欧美牲交a欧牲交aⅴ久久| 人妻少妇偷人精品无码| 丁香五月缴情在线| 好爽...又高潮了毛片| av东京热无码专区| 69久久精品无码一区二区| 国产成人精品福利一区二区三区 | 国产丝袜视频一区二区三区| 亚洲一区二区观看播放| 亚洲人成人伊人成综合网无码| 性按摩无码中文| 国产精品久久久久久久久久久免费看| 中文字幕av无码不卡| 久久九九兔免费精品6| 久久996re热这里有精品| 毛片免费视频观看| 无套内射视频囯产| 末发育娇小性色xxxxx| 国产卡1卡2卡3麻豆精品免费| 国模无码视频一区二区三区| 成人亚洲a片v一区二区三区蜜臀 | 欧美日韩精品一区二区性色a+v| 又色又爽又黄18禁美女裸身无遮挡 | 亚洲中文字幕无码一久久区| 成人免费午夜无码视频在线播放 | 久久久精品人妻一区二区三区| 五月综合色婷婷在线观看| 大战丰满无码人妻50p| 99精品视频九九精品视频| 日本成本人片视频免费| 欧美精品亚洲精品日韩专区| 少妇久久久久久被弄高潮 | 天天综合亚洲色在线精品| 人妻人人看人妻人人添| 野外做受三级视频| 天天干天天日| 国产在线观看高清视频黄网| 西西人体大胆午夜视频|