在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PSMB7 Antibody

  • 中文名稱:
    PSMB7兔多克隆抗體
  • 貨號:
    CSB-PA955584
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA955584(PSMB7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA955584(PSMB7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human testis tissue, mouse brain tissue, Primary antibody: CSB-PA955584(PSMB7 Antibody) at dilution 1/310, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    PSMB7
  • 別名:
    Macropain chain Z antibody; Multicatalytic endopeptidase complex chain Z antibody; Proteasome (prosome macropain) subunit beta type 7 antibody; Proteasome beta 7 subunit antibody; Proteasome catalytic subunit 2 antibody; Proteasome subunit alpha antibody; Proteasome subunit beta 7 antibody; Proteasome subunit beta type-7 antibody; Proteasome subunit Z antibody; PSB7_HUMAN antibody; PSMB7 antibody; PUP1 antibody; Z antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human PSMB7
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
  • 基因功能參考文獻:
    1. Studied the associations of Protein Z (PROZ G79A) and Endothelin-1 (EDN1 G5665T) polymorphisms with the clinical features of sickle cell disease (SCD) in a cohort of Egyptian children with SCD. PMID: 28548215
    2. reduced protein levels in patients with rheumatoid arthritis in association with disease progression PMID: 21713324
    3. high PSMB7 expression is associated with anthracycline resistance in breast cancer. PMID: 20010949
    4. Low protein Z levels but not protein Z gene G79A polymorphism are a risk factor for ischemic stroke. PMID: 18378283
    5. A previously unreported sporadic missense mutation within exon 8 is described in a patient with very low protein Z levels. PMID: 18462727
    6. PSB7, PRDX1, and SRP9 up-regulation as candidate biomarkers of colon cancer is discovered PMID: 18549262
    7. ZPI functions like other serpins to regulate the activity of FXa but in a manner uniquely dependent on protein Z, procoagulant membranes, and pH PMID: 18768472
    8. we have identified and characterized a new phosphorylated isoform of the human 20S proteasome b7 subunit and showed its differential expression in tumor vs. normal cell lines PMID: 19645816

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Peptidase T1B family
  • 組織特異性:
    Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
  • 數據庫鏈接:

    HGNC: 9544

    OMIM: 604030

    KEGG: hsa:5695

    STRING: 9606.ENSP00000259457

    UniGene: Hs.213470



主站蜘蛛池模板: 久久国产劲爆∧v内射-百度| 亚洲一区二区三区四区五区六区 | 亚无码乱人伦一区二区| 欧美黑人巨大videos精品男男| 亚州性无码不卡免费视频| 欧美性大战久久久久xxx| 欧美人做人爱a全程免费| 插鸡网站在线播放免费观看| 在线人成免费视频69国产| 日日摸日日碰夜夜爽亚洲| 高中生自慰www网站| 日本熟日本熟妇在线视频| 色香阁综合无码国产在线| 少妇人妻大乳在线视频| 国产麻豆md传媒视频| 国产精品久人妻精品| 女人爽到高潮视频免费直播| 亚洲国产精品一区二区成人片 | 成人免费看www网址入口 | 亚洲综合无码一区二区痴汉| 永久免费看啪啪网址入口| 伊人色综合一区二区三区| 欧美孕妇变态孕交粗暴| 99久久国产综合精品1| 大肉大捧一进一出好爽视色大师| 欧美激情一区二区三区高清视频| 亚洲成a人片在线播放| 亚洲精品久久久久午夜福利| 亚洲欧美日韩在线不卡| 精品av国产一二三四区| 亚洲无线码一区二区三区| 无码精品a∨在线观看中文| 天天爽夜夜爽夜夜爽精品视频| 国产成人精品一区二区视频 | 国产丝袜视频一区二区三区| 亚洲乱码中文字幕久久孕妇黑人| 久久天天躁夜夜躁狠狠综合| 国产精品天天狠天天看| 一卡二卡三卡视频| 波多野结衣爽到高潮大喷| 极品人妻少妇一区二区三区|