在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Probable dimethyladenosine transferase (DIMT1)

  • 中文名稱:
    人DIMT1重組蛋白
  • 貨號:
    CSB-EP892161HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    DIMT1
  • Uniprot No.:
  • 別名:
    18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; 18S rRNA dimethylase; DIM1; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae); DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1 like ; DIM1 dimethyladenosine transferase 1-like; Dimethyladenosine transferase; DIMT1; DIMT1_HUMAN; DIMT1L; HSA9761; HUSSY5; N''-adenosyl(rRNA) dimethyltransferase; Probable 18S rRNA (adenine(1779) N(6)/adenine(1780) N(6)) dimethyltransferase; Probable 18S rRNA dimethylase; Probable dimethyladenosine transferase; Probable S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase; S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase; S-adenosylmethionine-6-N''
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    51.2kDa
  • 表達區域:
    1-313aa
  • 氨基酸序列
    MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity.
  • 基因功能參考文獻:
    1. DIMT1 is overexpressed in gastric carcinoma and is significantly correlated with poor prognosis. PMID: 28601661
    2. Studies show that miroRNA miR-210 acts as a tumor suppressor in hypoxic conditions by downregulating the 18S rRNA base methyltransferase (DIMT1)-interferon regulatory factor 4 (IRF4) axis. PMID: 28164410
    3. DIMT1L and WBSCR22-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity. PMID: 25851604
    4. Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection by activating STMN1 and DIMT1. PMID: 25187177
  • 亞細胞定位:
    Nucleus, nucleoplasm. Nucleus, nucleolus.
  • 蛋白家族:
    Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family
  • 數據庫鏈接:

    HGNC: 30217

    OMIM: 612499

    KEGG: hsa:27292

    STRING: 9606.ENSP00000199320

    UniGene: Hs.731665



主站蜘蛛池模板: 精品国内综合一区二区| 中国少妇偷人hd| 亚洲国产精品va在线观看麻豆| 熟妇人妻不卡中文字幕| 亚洲国产精久久久久久久| 亚洲国产欧美在线观看| 久久久国产一区二区三区四区小说| 国产又爽又黄又不遮挡视频| 99热亚洲色精品国产88| 精品性影院一区二区三区内射| 久久精品人妻中文系列| 少妇中文字幕乱码亚洲影视 | 国产在线国偷精品免费看| 亚洲欧美精品伊人久久| 亚洲狠狠成人网| 国产好吊看视频在线观看| 精品一区国产vr| 美丽的熟妇中文字幕| 18禁裸乳无遮挡啪啪无码免费| 人人澡人摸人人添| 亚洲一区二区无码影院| 国产人妻久久精品二区三区老狼| 无码日韩精品一区二区免费| 欧美肥熟妇xxxxx| 国产高清女同学巨大乳在线观看| 国产亚洲精品久久一区二区| 国产精品福利一区二区| 无码熟妇人妻av在线影片| 美乳丰满人妻无码视频| 国产成人无码av大片大片在线观看| 五十路熟女一区二区三区| 一出一进一爽一粗一大视频| 亚洲人av在线无码影院观看| 欧美丰满大乳高跟鞋| 亚洲久久久久久中文字幕| 日本视频高清一道一区| 最新69国产成人精品视频免费| 久久99精品国产99久久6| 丰满熟妇乱子伦| 黑人大荫蒂高潮视频| 国产精品女同一区二区在线|