在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 14 (GALNT14), partial

  • 中文名稱:
    人GALNT14重組蛋白
  • 貨號:
    CSB-YP836212HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GALNT14重組蛋白
  • 貨號:
    CSB-EP836212HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GALNT14重組蛋白
  • 貨號:
    CSB-BP836212HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GALNT14重組蛋白
  • 貨號:
    CSB-MP836212HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GALNT14
  • Uniprot No.:
  • 別名:
    GalNAc T14; GalNAc-T14; Galnt14; GLT14_HUMAN; Polypeptide GalNAc transferase 14; Polypeptide N acetylgalactosaminyltransferase 14; Polypeptide N-acetylgalactosaminyltransferase 14; pp GaNTase 14; pp-GaNTase 14; Protein UDP acetylgalactosaminyltransferase 14; Protein-UDP acetylgalactosaminyltransferase 14; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 14 ; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.
  • 基因功能參考文獻:
    1. Silencing of GALNT14 in osterix-overexpressed cells restored the decreased chemosensitivity. Conversely, overexpression of GALNT14 in osterix-knockdown cells abrogated the increased chemosensitivity in breast cancer cells. PMID: 29227978
    2. The analysis showed that the "TT" genotype was associated with unfavorable overall survival (OS, P = 0.009). PMID: 27124048
    3. miR-125a functions as tumor suppressor in ovarian cancer by targeting GALNT14. PMID: 27133078
    4. GALNT14 genotypes were significantly associated with clinical outcomes of transcatheter arterial chemoembolization. PMID: 26871639
    5. Expression of GalNAc-T14 or HOXB9 was strongly correlated with reduced recurrence-free survival in lung adenocarcinomas. PMID: 26544896
    6. Recurrence of mutation suggests GALNT14 as a novel gene potentially involved in neuroblastoma predisposition. PMID: 26309160
    7. GALNT14 stimulates MMP-2 expression. PMID: 24962947
    8. GALN14 genotype (rs9679162) was an effective predictor for therapeutic outcome in advanced hepatocellular carcinoma (HCC) patients treated by FMP chemotherapy. PMID: 23959947
    9. Studies demonstrate that IGFBP-3 and GalNAc-T14 are colocalized in MCF-7 cells, and confirmed the interaction between IGFBP-3 and GalNAc-T14; these results reveal a minimal region of GalNAc-T14 that was sufficiently bound to the full-length IGFBP-3. PMID: 22441125
    10. Results provide evidence that GalNAc-T14 may be a potential biomarker for breast cancer by immunohistochemistry. PMID: 20356418
    11. GALNT14 and FUT3/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines PMID: 20179215
    12. cloning and characterization; results provide evidence that pp-GalNAc-T14 is a new member of the pp-GalNAc-T family and suggest that it may be involved in the O-glycosylation in kidney PMID: 12507512
    13. The role of GalNAc-T14 as an intracellular mediator of the effects of IGFBP-3 need to be verified in future studies. PMID: 17434446
    14. GALNT14 may be involved in regulating the apoptotic action of IGFBP-3. PMID: 19805900

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性:
    Detected in renal tubules (at protein level). Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bl
  • 數據庫鏈接:

    HGNC: 22946

    OMIM: 608225

    KEGG: hsa:79623

    STRING: 9606.ENSP00000288988

    UniGene: Hs.468058



主站蜘蛛池模板: 国产精品视频观看裸模| 亚洲日韩久热中文字幕| av无码天堂一区二区三区| 午夜高清国产拍精品| 日本中文字幕亚洲乱码| 亚洲18色成人网站www| 亚洲夜色噜噜av在线观看| 亚洲成av人片在线观看一区二区三区 | 欧美巨大xxxx做受高清| 又大又粗又爽免费视频a片| 国产综合久久亚洲综合| 丰满人妻熟妇乱又伦精品| 成人试看30分钟免费视频| 99热这里只有精品国产免费免费| av无码精品一区二区三区四区| 国产成人精品一区二三区在线观看| 加勒比无码人妻东京热| 日日大香人伊一本线久| 久久久久久久久久久久久9999 | 国产又滑又嫩又白| 狠狠色丁香久久婷婷综合图片| 一本久道久久综合久久爱| 强行从后面挺进人妻| 高级会所人妻互换94部分| 黑人猛挺进小莹的体内视频| 国产偷国产偷亚洲清高孕妇| 国产午夜精品一区二区三区不卡| 日本簧片在线观看| 中字幕视频在线永久在线| 最新精品国偷自产在线美女足| 五月开心播播网| 无码专区—va亚洲v天堂麻豆| 无码av喷白浆在线播放| 国产一码二码三码区别| 狠狠色噜噜狠狠狠狠av不卡| 久久久女人与动物群交毛片| 国产特级毛片aaaaaa高清| 久久er99热精品一区二区| 中文av伊人av无码av狼人| 少妇人妻丰满做爰xxx| 996久久国产精品线观看|