在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GALNT14 Antibody

GALNT14 Antibody

  • 中文名稱：
    GALNT14兔多克隆抗體
  • 貨號：
    CSB-PA836212LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: GALNT14 antibody at 2µg/ml
      Lane 1: Rat gonad tissue
      Lane 2: Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 65, 61, 62 kDa
      Observed band size: 65 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA836212LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GALNT14 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALNT14
  • 別名：
    GalNAc T14 antibody; GalNAc-T14 antibody; Galnt14 antibody; GLT14_HUMAN antibody; Polypeptide GalNAc transferase 14 antibody; Polypeptide N acetylgalactosaminyltransferase 14 antibody; Polypeptide N-acetylgalactosaminyltransferase 14 antibody; pp GaNTase 14 antibody; pp-GaNTase 14 antibody; Protein UDP acetylgalactosaminyltransferase 14 antibody; Protein-UDP acetylgalactosaminyltransferase 14 antibody; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 14 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 14 protein (1-552AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，GALNT14 Antibody (CSB-PA836212LA01HU)，的標記方式是Non-conjugated。對于GALNT14 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA836212LB01HU GALNT14 Antibody, HRP conjugated ELISA
    FITC CSB-PA836212LC01HU GALNT14 Antibody, FITC conjugated
    Biotin CSB-PA836212LD01HU GALNT14 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.
  • 基因功能參考文獻：
    1. Silencing of GALNT14 in osterix-overexpressed cells restored the decreased chemosensitivity. Conversely, overexpression of GALNT14 in osterix-knockdown cells abrogated the increased chemosensitivity in breast cancer cells. PMID: 29227978
    2. The analysis showed that the "TT" genotype was associated with unfavorable overall survival (OS, P = 0.009). PMID: 27124048
    3. miR-125a functions as tumor suppressor in ovarian cancer by targeting GALNT14. PMID: 27133078
    4. GALNT14 genotypes were significantly associated with clinical outcomes of transcatheter arterial chemoembolization. PMID: 26871639
    5. Expression of GalNAc-T14 or HOXB9 was strongly correlated with reduced recurrence-free survival in lung adenocarcinomas. PMID: 26544896
    6. Recurrence of mutation suggests GALNT14 as a novel gene potentially involved in neuroblastoma predisposition. PMID: 26309160
    7. GALNT14 stimulates MMP-2 expression. PMID: 24962947
    8. GALN14 genotype (rs9679162) was an effective predictor for therapeutic outcome in advanced hepatocellular carcinoma (HCC) patients treated by FMP chemotherapy. PMID: 23959947
    9. Studies demonstrate that IGFBP-3 and GalNAc-T14 are colocalized in MCF-7 cells, and confirmed the interaction between IGFBP-3 and GalNAc-T14; these results reveal a minimal region of GalNAc-T14 that was sufficiently bound to the full-length IGFBP-3. PMID: 22441125
    10. Results provide evidence that GalNAc-T14 may be a potential biomarker for breast cancer by immunohistochemistry. PMID: 20356418
    11. GALNT14 and FUT3/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines PMID: 20179215
    12. cloning and characterization; results provide evidence that pp-GalNAc-T14 is a new member of the pp-GalNAc-T family and suggest that it may be involved in the O-glycosylation in kidney PMID: 12507512
    13. The role of GalNAc-T14 as an intracellular mediator of the effects of IGFBP-3 need to be verified in future studies. PMID: 17434446
    14. GALNT14 may be involved in regulating the apoptotic action of IGFBP-3. PMID: 19805900

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Detected in renal tubules (at protein level). Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bl
  • 數據庫鏈接：

    HGNC: 22946

    OMIM: 608225

    KEGG: hsa:79623

    STRING: 9606.ENSP00000288988

    UniGene: Hs.468058



主站蜘蛛池模板： 下面一进一出好爽视频| 忘忧草社区在线资源www| 我的性奴的肉玩具1一17心奴| 人妻丰满熟妇av无码区动漫| 欧美性猛交xxxx黑人猛交 | 男女作爱免费网站| 99精品国产再热久久无毒不卡| 中文字幕av无码不卡免费| 在线天堂资源www| 欧美激情视频一区二区三区免费| 国产午夜福利100集发布| 国产69精品久久久久久妇女迅雷| 永久免费无码av在线网站| 亚洲日韩一区二区| 欧美乱色伦图片区| 青青草无码免费一二三区| 亚洲精品国产一区二区图片 | 少妇被黑人4p到惨叫欧美人| 中文无码精品一区二区三区| 亚洲精品97久久中文字幕无码| 日本丰满熟妇bbxbbxhd| 欧洲人免费视频网站在线| 中文国产成人精品久久app| 精品无码一区二区三区在线| 国产寡妇偷人在线观看| 人妻中出无码一区二区三区| 国产内射老熟女aaaa| 99久久国产露脸国语对白| 日产精品高潮呻吟av久久| 国产av成人无码精品网站| 伴郎粗大的内捧猛烈进出视频观看| 俄罗斯美女真人性做爰| 亚洲精品国产一区二区三| 中国真实偷乱视频| 韩国理伦片一区二区三区在线播放| 在线岛国片免费无码av| 午夜福利免费0948视频| 中文字幕日韩一区二区三区不卡| 国产做爰xxxⅹ高潮视频12p| 国产多人群p刺激交换视频| 好吊色欧美一区二区三区视频 |