在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GALNT14 Antibody

GALNT14 Antibody

  • 中文名稱：
    GALNT14兔多克隆抗體
  • 貨號：
    CSB-PA836212LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: GALNT14 antibody at 2µg/ml
      Lane 1: Rat gonad tissue
      Lane 2: Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 65, 61, 62 kDa
      Observed band size: 65 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA836212LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GALNT14 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALNT14
  • 別名：
    GalNAc T14 antibody; GalNAc-T14 antibody; Galnt14 antibody; GLT14_HUMAN antibody; Polypeptide GalNAc transferase 14 antibody; Polypeptide N acetylgalactosaminyltransferase 14 antibody; Polypeptide N-acetylgalactosaminyltransferase 14 antibody; pp GaNTase 14 antibody; pp-GaNTase 14 antibody; Protein UDP acetylgalactosaminyltransferase 14 antibody; Protein-UDP acetylgalactosaminyltransferase 14 antibody; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 14 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 14 protein (1-552AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，GALNT14 Antibody (CSB-PA836212LA01HU)，的標記方式是Non-conjugated。對于GALNT14 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA836212LB01HU GALNT14 Antibody, HRP conjugated ELISA
    FITC CSB-PA836212LC01HU GALNT14 Antibody, FITC conjugated
    Biotin CSB-PA836212LD01HU GALNT14 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.
  • 基因功能參考文獻：
    1. Silencing of GALNT14 in osterix-overexpressed cells restored the decreased chemosensitivity. Conversely, overexpression of GALNT14 in osterix-knockdown cells abrogated the increased chemosensitivity in breast cancer cells. PMID: 29227978
    2. The analysis showed that the "TT" genotype was associated with unfavorable overall survival (OS, P = 0.009). PMID: 27124048
    3. miR-125a functions as tumor suppressor in ovarian cancer by targeting GALNT14. PMID: 27133078
    4. GALNT14 genotypes were significantly associated with clinical outcomes of transcatheter arterial chemoembolization. PMID: 26871639
    5. Expression of GalNAc-T14 or HOXB9 was strongly correlated with reduced recurrence-free survival in lung adenocarcinomas. PMID: 26544896
    6. Recurrence of mutation suggests GALNT14 as a novel gene potentially involved in neuroblastoma predisposition. PMID: 26309160
    7. GALNT14 stimulates MMP-2 expression. PMID: 24962947
    8. GALN14 genotype (rs9679162) was an effective predictor for therapeutic outcome in advanced hepatocellular carcinoma (HCC) patients treated by FMP chemotherapy. PMID: 23959947
    9. Studies demonstrate that IGFBP-3 and GalNAc-T14 are colocalized in MCF-7 cells, and confirmed the interaction between IGFBP-3 and GalNAc-T14; these results reveal a minimal region of GalNAc-T14 that was sufficiently bound to the full-length IGFBP-3. PMID: 22441125
    10. Results provide evidence that GalNAc-T14 may be a potential biomarker for breast cancer by immunohistochemistry. PMID: 20356418
    11. GALNT14 and FUT3/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines PMID: 20179215
    12. cloning and characterization; results provide evidence that pp-GalNAc-T14 is a new member of the pp-GalNAc-T family and suggest that it may be involved in the O-glycosylation in kidney PMID: 12507512
    13. The role of GalNAc-T14 as an intracellular mediator of the effects of IGFBP-3 need to be verified in future studies. PMID: 17434446
    14. GALNT14 may be involved in regulating the apoptotic action of IGFBP-3. PMID: 19805900

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Detected in renal tubules (at protein level). Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bl
  • 數據庫鏈接：

    HGNC: 22946

    OMIM: 608225

    KEGG: hsa:79623

    STRING: 9606.ENSP00000288988

    UniGene: Hs.468058



主站蜘蛛池模板： 亚洲丁香婷婷久久一区二区| 双乳被一左一右吃着动态图| 国内少妇高潮嗷嗷叫在线播放| 四虎av永久在线精品免费观看| 射死你天天日| 亚洲视频日本有码中文| 体验区试看120秒啪啪免费| 久久无码av一区二区三区电影网| 免费人妻av无码专区| 欧美又大又粗午夜剧场免费| 日本一卡2卡3卡4卡免费精品| 国内老熟妇乱子伦视频| 亚洲欧洲日产国码无码av一| 欧美人与动牲交a欧美| 国产精品天干天干在线综合| 亚洲国产精品无码观看久久| 麻豆精产国品| 2018天天躁夜夜躁狠狠躁| 精品国产午夜福利在线观看| 少妇被粗大的猛烈进出视频| 国产精品久久精品国产| 国产精品女主播主要上线| 小草社区视频在线观看| 欧美大成色www永久网站婷| 亚洲一卡2卡三卡四卡精品| 国内精品久久久久久无码| 国产成年无码久久久久毛片| 四虎影视永久地址www成人| 午夜尤物禁止18点击进入| 亚洲欲色欲香天天综合网| 日韩欧美猛交xxxxx无码| 国产成人精品成人a在线观看| 欧美自拍亚洲综合丝袜| 亚洲国产成人久久综合区| 欧美性猛交xxxx乱大交极品| 亚洲精品国产自在现线看| av制服丝袜白丝国产网站| 欧美国产激情18| 高清性欧美暴力猛交| 国产人妻人伦精品久久久| 国产98色在线 | 国产|