在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Poliovirus receptor-related protein 3 (PVRL3), partial

  • 中文名稱:
    人NECTIN3重組蛋白
  • 貨號:
    CSB-YP882076HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NECTIN3重組蛋白
  • 貨號:
    CSB-EP882076HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NECTIN3重組蛋白
  • 貨號:
    CSB-EP882076HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NECTIN3重組蛋白
  • 貨號:
    CSB-BP882076HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NECTIN3重組蛋白
  • 貨號:
    CSB-MP882076HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CD113; CDw113; DKFZP566B0846; FLJ90624; Nectin-3; Nectin3; Poliovirus receptor related 3; Poliovirus receptor related protein 3; Poliovirus receptor-like 3; Poliovirus receptor-related protein 3; PPR3; PRR3; Pvrl3; PVRL3_HUMAN; PVRR3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
  • 基因功能參考文獻:
    1. Nectin-3 mutation in men with severe teratospermia PMID: 28689229
    2. Data suggest that 3 independent regions of TcdB (Clostridium difficile toxin B; 1372-1493, 1493-1848, 1851-2366) contribute to binding and entry of TcdB into mammalian cells; residues 1372-1493 are sufficient for interaction with PVRL3. PMID: 26602083
    3. Expression of nectin-3 in pancreatic cancer can be a prognostic factor. PMID: 25690753
    4. PVRL3 is a physiologically relevant binding partner that can serve as a target for the prevention of TcdB-induced cytotoxicity in C. difficile infection. PMID: 26038560
    5. Nectin-3 is associated with the formation of cell junctions and be a putative suppressor molecule to the invasion of breast cancer cells. PMID: 24386110
    6. Nectin-3 trans-interacts with Nectin-2 to promote lymphocyte and monocyte extravasation. PMID: 24116228
    7. Data suggest that expression of nectin-3 is up-regulated in eutopic endometrium of patients with endometriosis as compared with control subjects and up-regulated in all endometriotic lesions investigated compared with eutopic endometrium. PMID: 22926846

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.
  • 蛋白家族:
    Nectin family
  • 組織特異性:
    Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.
  • 數據庫鏈接:

    HGNC: 17664

    OMIM: 607147

    KEGG: hsa:25945

    STRING: 9606.ENSP00000418070

    UniGene: Hs.293917



主站蜘蛛池模板: 女被啪到深处喷水gif动态图 | 亚洲 日韩 欧美 成人 在线观看| 国产精品无码日韩欧| 又色又爽又高潮免费观看| 中文字幕久精品免费视频| 亚洲乱妇亚洲乱妇xinglu| 九九久久精品无码专区| 欧美人与禽猛交狂配| 亚洲高清国产av拍精品青青草原| 天堂va视频一区二区| 色婷婷综合缴情综免费观看| 东北妇女精品bbwbbw| 国产成人综合色视频精品| 久久九九精品国产免费看小说 | 吸咬奶头狂揉60分钟视频| 亚洲最大日夜无码中文字幕| 18禁美女黄网站色大片免费网站 | 国产成人精品午夜福利| 中文字幕亚洲制服在线看| 精品无人乱码高清在线观看 | 亚洲欧洲日本综合aⅴ在线| 国产裸体舞一区二区三区 | 日产精品一区二区| 欧洲精品欧美精品| 在线视频免费无码专区| 国产亚洲欧美精品永久| 免费ā片在线观看| 在线高清亚洲精品二区| 免费不卡无码av在线观看| 午夜精品久久久久久久喷水| 中文在线а√天堂| av狼友无码国产在线观看| 衣服被扒开强摸双乳18禁网站| 亚洲爆乳少妇无码激情| 日本簧片在线观看| av影音先锋最大资源网| 久久97精品久久久久久久不卡| 少妇高潮惨叫久久久久久| 成人无码男男gv在线观看网站| 综合偷自拍亚洲乱中文字幕| 吃奶呻吟打开双腿做受动态图|