在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Patatin-like phospholipase domain-containing protein 4 (PNPLA4)

  • 中文名稱:
    人PNPLA4重組蛋白
  • 貨號:
    CSB-YP018283HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PNPLA4重組蛋白
  • 貨號:
    CSB-EP018283HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PNPLA4重組蛋白
  • 貨號:
    CSB-BP018283HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PNPLA4重組蛋白
  • 貨號:
    CSB-MP018283HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PNPLA4
  • Uniprot No.:
  • 別名:
    Calcium independent phospholipases A2 eta; DXS1283E; GS2; IPLA2 eta; Patatin-like phospholipase domain-containing protein 4; PLPL4_HUMAN; PNPLA4; Protein GS2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-253
  • 氨基酸序列
    MKHINLSFAA CGFLGIYHLG AASALCRHGK KLVKDVKAFA GASAGSLVAS VLLTAPEKIE ECNQFTYKFA EEIRRQSFGA VTPGYDFMAR LRSGMESILP PSAHELAQNR LHVSITNAKT RENHLVSTFS SREDLIKVLL ASSFVPIYAG LKLVEYKGQK WVDGGLTNAL PILPVGRTVT ISPFSGRLDI SPQDKGQLDL YVNIAKQDIM LSLANLVRLN QALFPPSKRK MESLYQCGFD DTVKFLLKEN WFE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Has abundant triacylglycerol lipase activity. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides.
  • 基因功能參考文獻:
    1. These results strongly suggest that PNPLA9, -6 and -4 play a key role in GPL turnover and homeostasis in human cells. A hypothetical model suggesting how these enzymes could recognize the relative concentration of the different GPLs is proposed PMID: 27317427
    2. iPLA2epsilon (adiponutrin), iPLA2zeta (TTS-2.2), and iPLA2eta (GS2) are three novel TAG lipases/acylglycerol transacylases that likely participate in TAG hydrolysis and the acyl-CoA independent transacylation of acylglycerols PMID: 15364929
    3. The GS2 gene (PNPLA4) encodes a keratinocyte retinyl ester hydrolase. The protein also catalyzes fatty acyl CoA-dependent and -independent retinol esterification, using triolein as substrate and generates diacylglyceride and free fatty acid. PMID: 15955102
    4. we report the identity of an inhibitor, TIP47, which prevents retinylester hydrolysis catalyzed by GS2 lipase and hormone-sensitive lipase PMID: 16741517
    5. GS2 promotes RE accumulation and may do so either as a catalyst or as a regulatory protein that enhances retinylesters formation catalyzed by other acyl transferases. PMID: 19181555
    6. No association between genetic variants in PNPLA4 genes and childhood and adolescent obesity PMID: 19390624

    顯示更多

    收起更多

  • 相關疾病:
    Defects in PNPLA4 may play a role in mitochondrial disorders characterized by complex IV deficiency.
  • 亞細胞定位:
    Mitochondrion.
  • 組織特異性:
    Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen.
  • 數據庫鏈接:

    HGNC: 24887

    OMIM: 300102

    KEGG: hsa:8228

    STRING: 9606.ENSP00000370430

    UniGene: Hs.264



主站蜘蛛池模板: 与子敌伦刺激对白播放| 亚洲暴爽av天天爽日日碰| 国产精品最新免费视频| 粉嫩小泬视频无码视频软件| 亚洲成aⅴ人片在线观| 色插图午夜影院| 国产精品一卡二卡三卡| 亚洲 丝袜 制服 欧美 另类| 羞涩的丰满人妻40p| 99久久99久久久精品齐齐| 免费无码av片在线观看播放| 性欧美疯狂xxxxbbbb| 真实国产精品视频400部| 人妻丰满熟av无码区hd| wwww亚洲熟妇久久久久| 在线无码中文字幕一区| 日韩av爽爽爽久久久久久| 午夜dy888国产精品影院| 22222se男人的天堂| 久久久受www免费人成| av在线 高清不卡区| 在线亚洲中文精品第1页| 国产又色又爽又刺激在线播放| julia无码中文字幕一区| 中文日韩亚洲欧美制服| 亚洲精品偷拍无码不卡av| 免费1级做爰片在线观看爱| 少妇放荡的呻吟干柴烈火免费视频| 久久精品丝袜高跟鞋| 97人洗澡从澡人人爽人人模| 极品少妇被弄得高潮不断| 少妇精品久久久一区二区三区| 伊人久久久精品区aaa片| 不卡无码av一区二区三区| 日韩视频无码免费一区=区三区| 亚洲综合在线一区二区三区| 国产精品9999久久久久仙踪林| 后进式无遮挡啪啪摇乳动态图| 天天爽夜夜爽人人爽88| 青春草在线视频观看| 成人免费看www网址入口|