Recombinant Human Patatin-like phospholipase domain-containing protein 4 (PNPLA4)
In Stock-
中文名稱:Recombinant Human Patatin-like phospholipase domain-containing protein 4 (PNPLA4)
-
貨號:CSB-EP018283HU
-
規(guī)格:¥1536
-
圖片:
-
其他:
產(chǎn)品詳情
-
純度:Greater than 90% as determined by SDS-PAGE.
-
生物活性:Not Test
-
基因名:PNPLA4
-
Uniprot No.:
-
別名:Calcium-independent phospholipase A2-eta;iPLA2-eta;EC 3.1.1.4;Protein GS2
-
種屬:Homo sapiens (Human)
-
蛋白長度:Full Length
-
來源:E.coli
-
分子量:29.1 kDa
-
表達(dá)區(qū)域:1-253aa
-
氨基酸序列MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIEECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKENWFE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering. -
蛋白標(biāo)簽:C-terminal 6xHis-tagged
-
產(chǎn)品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
-
復(fù)溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
-
儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保質(zhì)期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:3-7 business days
-
注意事項(xiàng):Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
-
Datasheet & COA:Please contact us to get it.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能:Has abundant triacylglycerol lipase activity. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides.
-
基因功能參考文獻(xiàn):
- These results strongly suggest that PNPLA9, -6 and -4 play a key role in GPL turnover and homeostasis in human cells. A hypothetical model suggesting how these enzymes could recognize the relative concentration of the different GPLs is proposed PMID: 27317427
- iPLA2epsilon (adiponutrin), iPLA2zeta (TTS-2.2), and iPLA2eta (GS2) are three novel TAG lipases/acylglycerol transacylases that likely participate in TAG hydrolysis and the acyl-CoA independent transacylation of acylglycerols PMID: 15364929
- The GS2 gene (PNPLA4) encodes a keratinocyte retinyl ester hydrolase. The protein also catalyzes fatty acyl CoA-dependent and -independent retinol esterification, using triolein as substrate and generates diacylglyceride and free fatty acid. PMID: 15955102
- we report the identity of an inhibitor, TIP47, which prevents retinylester hydrolysis catalyzed by GS2 lipase and hormone-sensitive lipase PMID: 16741517
- GS2 promotes RE accumulation and may do so either as a catalyst or as a regulatory protein that enhances retinylesters formation catalyzed by other acyl transferases. PMID: 19181555
- No association between genetic variants in PNPLA4 genes and childhood and adolescent obesity PMID: 19390624
顯示更多
收起更多
-
相關(guān)疾?。?/div>Defects in PNPLA4 may play a role in mitochondrial disorders characterized by complex IV deficiency.亞細(xì)胞定位:Mitochondrion.組織特異性:Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen.數(shù)據(jù)庫鏈接:
Most popular with customers
-
Recombinant Human papillomavirus type 16 Protein E7 (E7) (Active)
Express system: E.coli
Species: Human papillomavirus type 16
-
Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Tissue factor pathway inhibitor (TFPI), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human CD70 antigen (CD70), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Macaca fascicularis Gastric inhibitory polypeptide receptor (GIPR), partial (Active)
Express system: yeast
Species: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)