在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human PX domain-containing protein kinase-like protein (PXK)

Recombinant Human PX domain-containing protein kinase-like protein (PXK)

  • 中文名稱：
    人PXK重組蛋白
  • 貨號(hào)：
    CSB-YP770363HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PXK重組蛋白
  • 貨號(hào)：
    CSB-EP770363HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PXK重組蛋白
  • 貨號(hào)：
    CSB-EP770363HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PXK重組蛋白
  • 貨號(hào)：
    CSB-BP770363HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PXK重組蛋白
  • 貨號(hào)：
    CSB-MP770363HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PXK
  • Uniprot No.：
  • 別名：
    FLJ20335; K-ATPase; Modulator of Na; Modulator of Na K ATPase ; Modulator of Na K ATPase long form ; MONaKA; PX domain containing protein kinase like protein ; PX domain containing serine/threonine kinase ; PX domain-containing protein kinase-like protein; PX ser/thr kinase v2 ; PX serine/threonine kinase ; Pxk; PXK_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-578
  • 氨基酸序列
    MAFMEKPPAG KVLLDDTVPL TAAIEASQSL QSHTEYIIRV QRGISVENSW QIVRRYSDFD LLNNSLQIAG LSLPLPPKKL IGNMDREFIA ERQKGLQNYL NVITTNHILS NCELVKKFLD PNNYSANYTE IALQQVSMFF RSEPKWEVVE PLKDIGWRIR KKYFLMKIKN QPKERLVLSW ADLGPDKYLS DKDFQCLIKL LPSCLHPYIY RVTFATANES SALLIRMFNE KGTLKDLIYK AKPKDPFLKK YCNPKKIQGL ELQQIKTYGR QILEVLKFLH DKGFPYGHLH ASNVMLDGDT CRLLDLENSL LGLPSFYRSY FSQFRKINTL ESVDVHCFGH LLYEMTYGRP PDSVPVDSFP PAPSMAVVAV LESTLSCEAC KNGMPTISRL LQMPLFSDVL LTTSEKPQFK IPTKLKEALR IAKECIEKRL IEEQKQIHQH RRLTRAQSHH GSEEERKKRK ILARKKSKRS ALENSEEHSA KYSNSNNSAG SGASSPLTSP SSPTPPSTSG ISALPPPPPP PPPPAAPLPP ASTEAPAQLS SQAVNGMSRG ALLSSIQNFQ KGTLRKAKTC DHSAPKIG
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
  • 基因功能參考文獻(xiàn)：
    1. First described as part of human kinome analysis, named Slob after Drosophila ortholog. PMID: 15289607
    2. Two of these kinases that were classified as resistors were PX domain-containing serine/threonine kinase (PXK) and AP2-associated kinase 1 (AAK1), which promote receptor endocytosis and may enable cells to resist TRAIL-induced apoptosis PMID: 25852190
    3. genetic association study in Han population in China: Data suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated. PMID: 25596907
    4. Results confirm the genetic association of the locus 3p14.3 with systemic lupus erythematosus in Europeans and point to the ABHD6 and not PXK, as the major susceptibility gene in the region. PMID: 24534757
    5. study determined that the previously described systemic lupus erythematosus susceptibility loci PXK (P = 3.27 x 10(-11), OR = 1.20) and JAZF1 (P = 1.11 x 10(-8), OR = 1.13) are shared with systemic sclerosis PMID: 23740937
    6. The rs6445975 polymorphism of PXK and the rs2304256 polymorphism of tyrosine kinase 2 are associated with the development of systemic lupus erythematosus in Europeans PMID: 22592861
    7. The association of PXK rs6445975 with systemic lupus erythematosus that was previously observed in Caucasians was not replicated in Koreans or in Hong Kong Chinese. PMID: 21243490
    8. These results indicate that PXK plays a critical role in epidermal growth factor receptor trafficking through modulating ligand-induced ubiquitination of the receptor. PMID: 20086096
    9. MONaKA modulates brain Na,K-ATPase by binding tightly to its beta1 and beta3 subunits, and may thereby participate in the regulation of electrical excitability and synaptic transmission [MONaKA] PMID: 16135750
    10. study presents four new regions having genetic associations with systemic lupus erythematosus in women of European descent: ITGAM, KIAA1542, PXK and rs10798269 PMID: 18204446

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
  • 蛋白家族：
    Protein kinase superfamily
  • 組織特異性：
    Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 23326

    OMIM: 611450

    KEGG: hsa:54899

    STRING: 9606.ENSP00000348472

    UniGene: Hs.190544



主站蜘蛛池模板： 好爽别插了无码视频| 国模叶桐尿喷337p人体| 国产网红主播无码精品| 国产亚洲精品a在线| √8天堂资源地址中文在线| 青青久在线视观看视| 亚洲乱码日产精品bd| 在线成 人av影院| 少妇又紧又深又湿又爽视频| 乌克兰少妇videos高潮| 午夜精品久久久久久久爽| 无码免费午夜福利看片| 成在人线av无码免费漫画| 亚洲中文字幕乱码熟女在线| 精品人妻二区中文字幕| 国产一性一交一伦一a片| 国产成人精品三上悠亚| 久久久久国产精品人妻aⅴ院| 天堂在线最新版www中文| 热99re久久精品这里都是精品免费 | 制服 丝袜 亚洲 中文 综合| 国产美女露脸口爆吞精| 国内极度色诱视频网站| 亚洲精品国产精品国自产| 人人澡人摸人人添| 成人做爰高潮片免费视频| 国产熟女高潮视频| 国产自偷自偷免费一区| 人妻夜夜爽天天爽| 国产制服丝袜亚洲高清| 久久久肥妇熟女ⅹxxx毛片| 久久久无码精品亚洲日韩按摩| 51精品国产人成在线观看| 久久综合一色综合久久小蛇| 在线 国产 精品 蜜芽| 国产普通话对白刺激| 2018国产精华国产精品| 最新国产精品好看的精品| av无码天一区二区一三区| 欧美老熟妇欲乱高清视频 | 日韩精品无码专区免费视频|