在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PXK Antibody, Biotin conjugated

PXK Antibody, Biotin conjugated

  • 中文名稱：
    PXK兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA770363LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PXK Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PXK
  • 別名：
    FLJ20335 antibody; K-ATPase antibody; Modulator of Na antibody; Modulator of Na K ATPase antibody; Modulator of Na K ATPase long form antibody; MONaKA antibody; PX domain containing protein kinase like protein antibody; PX domain containing serine/threonine kinase antibody; PX domain-containing protein kinase-like protein antibody; PX ser/thr kinase v2 antibody; PX serine/threonine kinase antibody; Pxk antibody; PXK_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human PX domain-containing protein kinase-like protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
  • 基因功能參考文獻(xiàn)：
    1. First described as part of human kinome analysis, named Slob after Drosophila ortholog. PMID: 15289607
    2. Two of these kinases that were classified as resistors were PX domain-containing serine/threonine kinase (PXK) and AP2-associated kinase 1 (AAK1), which promote receptor endocytosis and may enable cells to resist TRAIL-induced apoptosis PMID: 25852190
    3. genetic association study in Han population in China: Data suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated. PMID: 25596907
    4. Results confirm the genetic association of the locus 3p14.3 with systemic lupus erythematosus in Europeans and point to the ABHD6 and not PXK, as the major susceptibility gene in the region. PMID: 24534757
    5. study determined that the previously described systemic lupus erythematosus susceptibility loci PXK (P = 3.27 x 10(-11), OR = 1.20) and JAZF1 (P = 1.11 x 10(-8), OR = 1.13) are shared with systemic sclerosis PMID: 23740937
    6. The rs6445975 polymorphism of PXK and the rs2304256 polymorphism of tyrosine kinase 2 are associated with the development of systemic lupus erythematosus in Europeans PMID: 22592861
    7. The association of PXK rs6445975 with systemic lupus erythematosus that was previously observed in Caucasians was not replicated in Koreans or in Hong Kong Chinese. PMID: 21243490
    8. These results indicate that PXK plays a critical role in epidermal growth factor receptor trafficking through modulating ligand-induced ubiquitination of the receptor. PMID: 20086096
    9. MONaKA modulates brain Na,K-ATPase by binding tightly to its beta1 and beta3 subunits, and may thereby participate in the regulation of electrical excitability and synaptic transmission [MONaKA] PMID: 16135750
    10. study presents four new regions having genetic associations with systemic lupus erythematosus in women of European descent: ITGAM, KIAA1542, PXK and rs10798269 PMID: 18204446

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
  • 蛋白家族：
    Protein kinase superfamily
  • 組織特異性：
    Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 23326

    OMIM: 611450

    KEGG: hsa:54899

    STRING: 9606.ENSP00000348472

    UniGene: Hs.190544



主站蜘蛛池模板： 国产毛多水多高潮高清| 日本一丰满一bbw| 国产亚洲欧洲日韩在线...| 亚洲乱码一卡二卡卡3卡4卡 | 人妻丰满av无码中文字幕| 国产v亚洲v天堂无码| 国产麻豆剧传媒精品国产av| 成人欧美一区二区三区黑人| 国产一区二区精品久久| 亚洲精品国产自在现线看| 人人爽人人澡人人人人妻| 成人性做爰aaa片免费| 精品国精品国产自在久国产应用| 老太婆性杂交视频| 国产真实自在自线免费精品| 日韩一区二区三区射精| 亚洲中文无码mv| 无码人妻一区二区三区av | 国产成人av一区二区三区| 少妇人妻综合久久中文字幕| 上司揉捏人妻丰满双乳电影| 久久伊99综合婷婷久久伊| 一本大道东京热无码视频| 少妇激情艳情综合小视频| av无码av天天av天天爽| 18禁无遮挡免费视频网站| 在线观看国产成人av天堂| 最新的国产成人精品2021| 97无码免费人妻超级碰碰碰碰| 果冻传媒18禁免费视频 | 亚洲欧洲日产韩国无码| 人人妻人人爽日日人人| 国产三级做爰在线播放| 亚洲欧美日韩精品久久亚洲区| 男女又色又爽又爽视频| 日韩成人无码v清免费| 亚洲国产丝袜精品一区| 亚洲精品无码国产片| 国产亚洲一区二区在线观看| 国产亚洲精品第一综合不卡| 欧洲亚洲色视频综合在线|