在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Nidogen-1 (NID1), partial

  • 中文名稱:
    人NID1重組蛋白
  • 貨號:
    CSB-YP015802HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NID1重組蛋白
  • 貨號:
    CSB-EP015802HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NID1重組蛋白
  • 貨號:
    CSB-EP015802HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NID1重組蛋白
  • 貨號:
    CSB-BP015802HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NID1重組蛋白
  • 貨號:
    CSB-MP015802HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    NID1
  • Uniprot No.:
  • 別名:
    Enactin; Ent; Entactin 1; Entactin; NID 1; NID; NID-1; Nid1; NID1_HUMAN; Nidogen (enactin); Nidogen 1; Nidogen; Nidogen-1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.
  • 基因功能參考文獻:
    1. Results demonstrated that NID1 was a mesenchymal associated gene and its high expression was significantly correlated with shorter overall survival of ovarian cancer patients. The study presents evidence that NID1 promotes the migration, invasion and chemoresistance of ovarian cancer cells via EMT and its molecular mechanism involves the activation of ERK/MAPK signaling. PMID: 28416770
    2. Nidogen 1 (NID1) was confirmed to promote lung metastasis of breast cancer and melanoma. PMID: 28827399
    3. nidogen-1 degraded by CatS can be quantified in serum by the NIC assay. The current data strongly suggest that cathepsin-S degradation of nidogen-1 is strongly associated with NSCLC, which needs validation in larger clinical cohorts. PMID: 28282545
    4. Differential protein expression of collagen IV, laminin alpha2, and nidogen-1 indicated basal lamina remodeling develops in ischemic failing versus nonfailing human hearts. PMID: 26756417
    5. NID1 was confirmed as a target gene of MiR-192/215 in Hirschsprung's disease patients. PMID: 25857602
    6. Increase of NID1 protein expression is associated with endometrial cancer invasion. PMID: 25924802
    7. The cleavage of nidogen-1 and -2 is partially inhibited in human tumor samples. PMID: 23681936
    8. results demonstrate that mutation in either NID1 or LAMC1 disrupts the interaction NID1-LAMC1 complex; findings implicate the extracellular matrix in the pathogenesis of Dandy-Walker spectrum disorders PMID: 23674478
    9. Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners PMID: 22952693
    10. NID1 gene is a biologically plausible locus for nevogenesis and melanoma development PMID: 21478494
    11. found to be ubiquitous component of basement membrane zones underneath developing epithelia of most of the major organ systems; may participate in cell biological functions during human development PMID: 12005023
    12. nidogen-2 is equivalent to nidogen-1 in skin-organotypic coculture, and both can promote the development of a functional basement membrane zone PMID: 17008882
    13. CpG islands of both NID1 and NID2 genes are aberrantly methylated in human cancer samples and cancer cell lines. PMID: 17328794

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 7821

    OMIM: 131390

    KEGG: hsa:4811

    STRING: 9606.ENSP00000264187

    UniGene: Hs.356624



主站蜘蛛池模板: 色综合亚洲一区二区小说性色aⅴ| 97夜夜澡人人爽人人喊a| 免费人成视频网站在线观看18| 亚洲成av人片天堂网九九| 国产一区二区三区无码免费| 国产精品久久久久久无毒不卡| 亚洲国色天香卡2卡3卡4| 男女啪啪无遮挡免费网站| 国产精品无码一区二区在线看| 日日噜噜噜噜夜夜爽亚洲精品| 亚洲人成精品久久久久| 国产成人亚洲综合青青| 色八区人妻在线视频免费| 国产成人精品一区二区秒拍| 欧美又粗又长又爽做受| 色欲av久久综合人妻无码| 精品国产三级a在线观看网站| 欧美精品免费观看二区| 精品人妻人人做人人爽| 18禁黄网站禁片免费观看国产| 无码人妻少妇久久中文字幕蜜桃 | 久久久精品人妻一区二区三区四| 播放男人添女人下边视频| 成年日韩片av在线网站| 中文字幕一区日韩精品| 色狠狠色狠狠综合天天| 亚洲一线二线三线写真| 2020年国产精品| 蜜桃av噜噜一区二区三区| 国产午国产午夜精华 免费| 九九热线有精品视频| 欧美成aⅴ人高清ww| 一本一道波多野结衣av中文| 三级在线看中文字幕完整版| 久久国产色欲av38| 韩国v欧美v亚洲v日本v| 国产熟妇搡bbbb搡bbbb搡| 国内精品久久久久影院免费| 精品国产福利拍拍拍| 欧美性生交大片18禁止| 少妇高潮太爽了在线视|