在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NID1 Antibody, HRP conjugated

  • 中文名稱:
    NID1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA015802LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NID1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    NID1
  • 別名:
    Enactin antibody; Ent antibody; Entactin 1 antibody; Entactin antibody; NID 1 antibody; NID antibody; NID-1 antibody; Nid1 antibody; NID1_HUMAN antibody; Nidogen (enactin) antibody; Nidogen 1 antibody; Nidogen antibody; Nidogen-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Nidogen-1 protein (792-942AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.
  • 基因功能參考文獻:
    1. Results demonstrated that NID1 was a mesenchymal associated gene and its high expression was significantly correlated with shorter overall survival of ovarian cancer patients. The study presents evidence that NID1 promotes the migration, invasion and chemoresistance of ovarian cancer cells via EMT and its molecular mechanism involves the activation of ERK/MAPK signaling. PMID: 28416770
    2. Nidogen 1 (NID1) was confirmed to promote lung metastasis of breast cancer and melanoma. PMID: 28827399
    3. nidogen-1 degraded by CatS can be quantified in serum by the NIC assay. The current data strongly suggest that cathepsin-S degradation of nidogen-1 is strongly associated with NSCLC, which needs validation in larger clinical cohorts. PMID: 28282545
    4. Differential protein expression of collagen IV, laminin alpha2, and nidogen-1 indicated basal lamina remodeling develops in ischemic failing versus nonfailing human hearts. PMID: 26756417
    5. NID1 was confirmed as a target gene of MiR-192/215 in Hirschsprung's disease patients. PMID: 25857602
    6. Increase of NID1 protein expression is associated with endometrial cancer invasion. PMID: 25924802
    7. The cleavage of nidogen-1 and -2 is partially inhibited in human tumor samples. PMID: 23681936
    8. results demonstrate that mutation in either NID1 or LAMC1 disrupts the interaction NID1-LAMC1 complex; findings implicate the extracellular matrix in the pathogenesis of Dandy-Walker spectrum disorders PMID: 23674478
    9. Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners PMID: 22952693
    10. NID1 gene is a biologically plausible locus for nevogenesis and melanoma development PMID: 21478494
    11. found to be ubiquitous component of basement membrane zones underneath developing epithelia of most of the major organ systems; may participate in cell biological functions during human development PMID: 12005023
    12. nidogen-2 is equivalent to nidogen-1 in skin-organotypic coculture, and both can promote the development of a functional basement membrane zone PMID: 17008882
    13. CpG islands of both NID1 and NID2 genes are aberrantly methylated in human cancer samples and cancer cell lines. PMID: 17328794

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 數據庫鏈接:

    HGNC: 7821

    OMIM: 131390

    KEGG: hsa:4811

    STRING: 9606.ENSP00000264187

    UniGene: Hs.356624



主站蜘蛛池模板: 国产精品欧美福利久久| 国产成人免费一区二区三区| 影音先锋无码aⅴ男人资源站| 999国内精品永久免费视频| 国产精品狼人久久久久影院| 欧美成人aaaa免费全部观看| 国产亚洲欧美日韩俺去了| 好吊妞国产欧美日韩免费观看| 啦啦啦中文在线观看日本| 久草热8精品视频在线观看| 亚洲一本一道一区二区三区| 在线看片福利无码网址| 对白脏话肉麻粗话av| s级爆乳玩具酱国产vip皮裤| 无码三级国产三级在线电影| 正在播放国产乱子伦最新视频| 欧美亚洲综合在线一区| 少妇又爽又刺激视频| 久久亚洲国产精品影院| 波多野结衣一区二区免费视频| 国产后入又长又硬| 日本肥老妇色xxxxx日本老妇| 玩弄放荡人妇系列av在线网站| 天堂va欧美ⅴa亚洲va在线| 一本色综合亚洲精品蜜桃冫| 无码人妻丰满熟妇啪啪| 欧美亚洲综合成人a∨在线| 国产精品女主播在线视频| 成人做爰视频www| 欧美自拍嘿咻内射在线观看| 2020每日更新国产精品视频| 天堂久久天堂av色综合| 日本熟妇乱子伦xxxx| 玩弄中年熟妇正在播放| 日本三级手机在线播放线观看 | 内射毛片内射国产夫妻| 超碰曰口干天天种夜夜爽| 国产成人av无码永久免费一线天| 国产真实的和子乱拍在线观看| 秋霞在线观看秋| 无码少妇一区二区浪潮免费|