在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Neuronal membrane glycoprotein M6-a (GPM6A), partial

  • 中文名稱:
    人GPM6A重組蛋白
  • 貨號:
    CSB-YP009722HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GPM6A重組蛋白
  • 貨號:
    CSB-EP009722HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GPM6A重組蛋白
  • 貨號:
    CSB-EP009722HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GPM6A重組蛋白
  • 貨號:
    CSB-BP009722HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GPM6A重組蛋白
  • 貨號:
    CSB-MP009722HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GPM6A
  • Uniprot No.:
  • 別名:
    GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
  • 基因功能參考文獻:
    1. HDAC5 emerges as a cellular conductor of MEF2C and M6a activity and is regulated by miR-124 and miR-9 to control neurite development. PMID: 28332716
    2. findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype PMID: 25224183
    3. Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B may act as novel oncogenes in the development of lymphoid leukemia. PMID: 24916915
    4. loosing dynamic regulation of neuronal GPM6A expression poses a genetic risk for claustrophobia PMID: 23632458
    5. GMP6A plays a role in the stress-induced hippocampal alterations that are found in psychiatric disorders in general and schizophrenia in particular. PMID: 18163405
    6. Results indicate that M6a modulates mu-opioid receptor endocytosis and post-endocytotic sorting and has an important role in receptor regulation. PMID: 18574501
    7. Results suggest that expression level of GPM6A is associated with the differentiation and neuronal migration of neurons derived from undifferentiated human embryonic stem cells. PMID: 19298174

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection.
  • 蛋白家族:
    Myelin proteolipid protein family
  • 數據庫鏈接:

    HGNC: 4460

    OMIM: 601275

    KEGG: hsa:2823

    STRING: 9606.ENSP00000280187

    UniGene: Hs.75819



主站蜘蛛池模板: 免费无码又爽又刺激高潮| 久久亚洲一区二区三区四区五区| 亚洲国产精彩中文乱码av| 亚洲精品无码av中文字幕电影网站 | 国产人妻精品一区二区三首| 国产麻无矿码直接观看| 亚洲精品乱码久久久久久金桔影视| 国产av无码专区亚洲awww| 18禁无码永久免费无限制网站 | 69风韵老熟女口爆吞精| 国产新婚夫妇叫床声不断| 久久综合香蕉国产蜜臀av| 国产一区二区女内射| 免费无码不卡中文字幕在线| 天堂在线最新版www中文| 浪货趴办公桌~h揉秘书电影| 色婷婷综合久久久久中文| 亚洲学生妹高清av| 玩弄少妇人妻| 亚洲www啪成人一区二区| 无码中文字幕波多野结衣| 亚洲成_人网站图片| 99国产精品久久久久久久日本竹| 免费人妻精品一区二区三区| 久久视频这里只精品| 欧美极品色午夜在线视频| 免费无码国产欧美久久18| 成人午夜福利视频镇东影视| 性xxxx欧美老妇胖老太269| 凸偷窥中国女人洗澡| 国产老熟女狂叫对白| 亚洲中文字幕无码久久2017| 亚洲欧美一区二区三区在线| 欧美黑人xxxx又粗又长| 性av无码天堂vr专区| 在线观看肉片av网站免费| 成人午夜视频精品一区| 国产免费一卡二卡三卡四卡| 高清同性男毛片| 亚洲精品无播放器在线播放| 美女高潮黄又色高清视频免费|