在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPM6A Antibody

GPM6A Antibody

  • 中文名稱：
    GPM6A兔多克隆抗體
  • 貨號：
    CSB-PA155584
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA155584(GPM6A Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA155584(GPM6A Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA155584(GPM6A Antibody) at dilution 1/950, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    GPM6A
  • 別名：
    GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human GPM6A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
  • 基因功能參考文獻：
    1. HDAC5 emerges as a cellular conductor of MEF2C and M6a activity and is regulated by miR-124 and miR-9 to control neurite development. PMID: 28332716
    2. findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype PMID: 25224183
    3. Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B may act as novel oncogenes in the development of lymphoid leukemia. PMID: 24916915
    4. loosing dynamic regulation of neuronal GPM6A expression poses a genetic risk for claustrophobia PMID: 23632458
    5. GMP6A plays a role in the stress-induced hippocampal alterations that are found in psychiatric disorders in general and schizophrenia in particular. PMID: 18163405
    6. Results indicate that M6a modulates mu-opioid receptor endocytosis and post-endocytotic sorting and has an important role in receptor regulation. PMID: 18574501
    7. Results suggest that expression level of GPM6A is associated with the differentiation and neuronal migration of neurons derived from undifferentiated human embryonic stem cells. PMID: 19298174

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection.
  • 蛋白家族：
    Myelin proteolipid protein family
  • 數據庫鏈接：

    HGNC: 4460

    OMIM: 601275

    KEGG: hsa:2823

    STRING: 9606.ENSP00000280187

    UniGene: Hs.75819



主站蜘蛛池模板： 日本少妇春药特殊按摩3| 精品国精品国产自在久国产应用| 伊伊综合在线视频无码| 亚洲日韩精品a∨片无码加勒比| 99久久久无码国产精品试看| 成 人色 网 站 欧美大片在线观看| 亚洲欧美在线人成最新| 中文字幕日本最新乱码视频| 亚洲 日韩 欧美 有码 在线| 亚洲欧洲久久av| av天堂亚洲区无码先锋影音| 免费观看全黄做爰大片国产| 苍井空张开腿实干12次| 99精品无码一区二区| 天天爽天天摸天天碰| 日韩av中文无码影院| 国产精品爽爽va吃奶在线观看 | 国产精品呻吟久久人妻无吗| 欧美粗大猛烈老熟妇| 欧美兽交xxxx×视频| 狠狠噜狠狠狠狠丁香五月| 婷婷射精av这里只有精品| 精品一区二区三区在线成人| 人人妻人人添人人爽欧美一区| 日韩精品一区二区三区影院| 国色天香精品一卡2卡3卡4| 日韩中文字幕在线专区| 一二区成人影院电影网| 天天天欲色欲色www免费| 日本护士毛茸茸xx| 免费不卡无码av在线观看| 精品av综合导航| 欧洲亚洲精品久久久久| 波多野结衣网站| 任你躁久久精品6| 国产精品卡一卡2卡3卡4| 亚洲精品国偷自产在线| 国产欧美久久一区二区三区| 成人亚洲一区无码久久| 日韩国产综合精选| 蜜臀av人妻国产精品建身房|