在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPM6A Antibody

GPM6A Antibody

  • 中文名稱：
    GPM6A兔多克隆抗體
  • 貨號：
    CSB-PA004657
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of rat stomach cells using M6A Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    GPM6A
  • 別名：
    GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human M6A.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
  • 基因功能參考文獻：
    1. HDAC5 emerges as a cellular conductor of MEF2C and M6a activity and is regulated by miR-124 and miR-9 to control neurite development. PMID: 28332716
    2. findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype PMID: 25224183
    3. Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B may act as novel oncogenes in the development of lymphoid leukemia. PMID: 24916915
    4. loosing dynamic regulation of neuronal GPM6A expression poses a genetic risk for claustrophobia PMID: 23632458
    5. GMP6A plays a role in the stress-induced hippocampal alterations that are found in psychiatric disorders in general and schizophrenia in particular. PMID: 18163405
    6. Results indicate that M6a modulates mu-opioid receptor endocytosis and post-endocytotic sorting and has an important role in receptor regulation. PMID: 18574501
    7. Results suggest that expression level of GPM6A is associated with the differentiation and neuronal migration of neurons derived from undifferentiated human embryonic stem cells. PMID: 19298174

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection.
  • 蛋白家族：
    Myelin proteolipid protein family
  • 數據庫鏈接：

    HGNC: 4460

    OMIM: 601275

    KEGG: hsa:2823

    STRING: 9606.ENSP00000280187

    UniGene: Hs.75819



主站蜘蛛池模板： 又色又爽又黄的美女裸体网站| 国产在线观看无码的免费网站| 男人边吻奶边挵进去视频| 国产一区视频一区欧美| 亚洲成_人网站图片| 国产又色又爽又黄的免费| 亚洲中文无码av在线| 国产又粗又硬又大爽黄老大爷视| 亚洲aⅴ无码专区在线观看| 在线无码免费的毛片视频| 亚洲欧美日韩另类精品一区| av无码一区二区三区| 无码免费毛片手机在线无卡顿| 国产精品99久久不卡| 国产嘿嘿嘿视频在线观看| 日韩午夜理论片 中文字幕 | 午夜影视啪啪免费体验区入口| 亚洲日本一区二区三区在线播放| 国产人妻xxxx精品hd| 日本熟人妻中文字幕在线| 少妇荡乳情欲办公室456视频 | 酒店大战丝袜高跟鞋人妻| 亚洲乱码国产乱码精品精大量| 欧美日韩亚洲tv不卡久久| 亚洲午夜久久久无码精品网红a片 国产亚洲日韩一区二区三区 | 中文在线中文a| 国产亚洲精品国产福利你懂的| 大胸美女被吃奶爽死视频| 欧美午夜精品一区二区三区电影| 人妻丰满熟妇av无码片| 国产又色又刺激高潮视频| 色欲香天天天综合网站| 亚洲产国偷v产偷v自拍色戒| 麻豆md0077饥渴少妇| 久久99精品网久久| 国产偷窥熟妇高潮呻吟| 无码少妇a片一区二区三区 | 免费人成视频网站在线观看18| 亚洲精品久久久久午夜aⅴ| 同性男男黄g片免费网站| аⅴ天堂中文在线网官网|