在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Negative elongation factor A (WHSC2)

Recombinant Human Negative elongation factor A (WHSC2)

  • 中文名稱：
    人NELFA重組蛋白
  • 貨號：
    CSB-YP867144HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NELFA重組蛋白
  • 貨號：
    CSB-EP867144HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NELFA重組蛋白
  • 貨號：
    CSB-EP867144HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NELFA重組蛋白
  • 貨號：
    CSB-BP867144HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NELFA重組蛋白
  • 貨號：
    CSB-MP867144HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NELFA
  • Uniprot No.：
  • 別名：
    FLJ10442; FLJ25112; Negative elongation factor A; Negative elongation factor polypeptide A ; NELF A; NELF-A; NELFA; NELFA_HUMAN; P/OKcl.15; P/OKcl15 ; WHSC 2; Whsc2; Wolf Hirschhorn syndrome candidate 2; Wolf Hirschhorn syndrome candidate 2 protein; Wolf-Hirschhorn syndrome candidate 2 protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-528
  • 氨基酸序列
    MASMRESDTG LWLHNKLGAT DELWAPPSIA SLLTAAVIDN IRLCFHGLSS AVKLKLLLGT LHLPRRTVDE MKGALMEIIQ LASLDSDPWV LMVADILKSF PDTGSLNLEL EEQNPNVQDI LGELREKVGE CEASAMLPLE CQYLNKNALT TLAGPLTPPV KHFQLKRKPK SATLRAELLQ KSTETAQQLK RSAGVPFHAK GRGLLRKMDT TTPLKGIPKQ APFRSPTAPS VFSPTGNRTP IPPSRTLLRK ERGVKLLDIS ELDMVGAGRE AKRRRKTLDA EVVEKPAKEE TVVENATPDY AAGLVSTQKL GSLNNEPALP STSYLPSTPS VVPASSYIPS SETPPAPSSR EASRPPEEPS APSPTLPAQF KQRAPMYNSG LSPATPTPAA PTSPLTPTTP PAVAPTTQTP PVAMVAPQTQ APAQQQPKKN LSLTREQMFA AQEMFKTANK VTRPEKALIL GFMAGSRENP CQEQGDVIQI KLSEHTEDLP KADGQGSTTM LVDTVFEMNY ATGQWTRFKK YKPMTNVS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.; (Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II.
  • 基因功能參考文獻：
    1. A positively charged face of NELF-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B. NELF-B is predicted to form a HEAT repeat fold, also binds RNA in vivo, and anchors the subunit NELF-E, which is confirmed to bind RNA in vivo. PMID: 27282391
    2. These studies allow us to position the actions of two new modulators of GR-regulated transactivation, NELF-A and NELF-B, relative to other factors in the overall gene induction sequence. PMID: 24097989
    3. data show that NELF subunits exhibit highly specific subcellular localizations, such as in NELF bodies or in midbodies, and some shuttle actively between the nucleus and cytoplasm; loss of NELF from cells can lead to enlarged and/or multiple nuclei PMID: 19245807
    4. haploinsufficiency of SLBP and/or WHSC2 (NELF-A) contributes to several novel cellular phenotypes of WHS. PMID: 22328085
    5. NELF-C and NELF-D are highly related or identical to the protein called TH1, of unknown function. NELF-B and NELF-C or NELF-D are integral subunits that bring NELF-A and NELF-E together. [NELF-B] [NELF-C] PMID: 12612062
    6. Negative elongation factor (NELF) is a four subunit transcription factor. Our results point to a surprising role of NELF in the 3' end processing of histone mRNAs and suggest that NELF is a new factor that coordinates mRNA processing in transcription PMID: 17499042

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NELF-A family
  • 組織特異性：
    Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney.
  • 數據庫鏈接：

    HGNC: 12768

    OMIM: 606026

    KEGG: hsa:7469

    STRING: 9606.ENSP00000372335

    UniGene: Hs.21771



主站蜘蛛池模板： 亚洲欧美日韩成人一区| 波多野结衣av手机在线观看| 鲁大师影院在线观看| 国产乱子经典视频在线观看| 欧洲 亚洲 国产图片综合 | 波多野结衣人妻| 精品人伦一区二区三区蜜桃免费| 精品无码av一区二区三区| 国产办公室无码视频在线观看| aaa午夜级特黄日本大片| 成人国产一区二区精品小说| 蜜桃视频无码区在线观看| 老司机午夜福利视频| 曰本大码熟中文字幕| 人妻少妇无码中文幕久久| 国产无套露脸在线观看| 人妻在线日韩免费视频| 国产性生交xxxxx免费| 很色很爽很黄裸乳视频| 亚洲中文有码字幕日本第一页| 欧美性受xxxxzooz乱毛| 亚洲国产精品一区二区美利坚| 日韩va中文字幕无码电影| 特黄特级毛片免费视频| 亚洲熟妇av一区二区三区浪潮 | 日韩综合夜夜香内射| 日韩人妻熟女中文字幕aⅴ春菜| 中日韩精品卡一卡二卡3卡| 最新在线精品国自产拍视频| 欧美性猛交ⅹxxx乱大交妖精| 苍井空亚洲精品aa片在线播放| 亚洲国产精品无码中文在线| 亚洲色欲在线播放一区| 特级毛片a片久久久久久| 久久青草费线频观看| 久久青青草原国产免费播放| aaa午夜级特黄日本大片| 国产精品视频一区二区噜噜| 国产精品免费一区二区三区四区| 国产日韩av无码免费一区二区| 久久成人网站亚洲综合|