在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NELFA Antibody

  • 中文名稱:
    NELFA兔多克隆抗體
  • 貨號:
    CSB-PA026111GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    NELFA
  • 別名:
    FLJ10442 antibody; FLJ25112 antibody; Negative elongation factor A antibody; Negative elongation factor polypeptide A antibody; NELF A antibody; NELF-A antibody; NELFA antibody; NELFA_HUMAN antibody; P/OKcl.15 antibody; P/OKcl15 antibody; WHSC 2 antibody; Whsc2 antibody; Wolf Hirschhorn syndrome candidate 2 antibody; Wolf Hirschhorn syndrome candidate 2 protein antibody; Wolf-Hirschhorn syndrome candidate 2 protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human NELF-A
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.; (Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II.
  • 基因功能參考文獻:
    1. A positively charged face of NELF-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B. NELF-B is predicted to form a HEAT repeat fold, also binds RNA in vivo, and anchors the subunit NELF-E, which is confirmed to bind RNA in vivo. PMID: 27282391
    2. These studies allow us to position the actions of two new modulators of GR-regulated transactivation, NELF-A and NELF-B, relative to other factors in the overall gene induction sequence. PMID: 24097989
    3. data show that NELF subunits exhibit highly specific subcellular localizations, such as in NELF bodies or in midbodies, and some shuttle actively between the nucleus and cytoplasm; loss of NELF from cells can lead to enlarged and/or multiple nuclei PMID: 19245807
    4. haploinsufficiency of SLBP and/or WHSC2 (NELF-A) contributes to several novel cellular phenotypes of WHS. PMID: 22328085
    5. NELF-C and NELF-D are highly related or identical to the protein called TH1, of unknown function. NELF-B and NELF-C or NELF-D are integral subunits that bring NELF-A and NELF-E together. [NELF-B] [NELF-C] PMID: 12612062
    6. Negative elongation factor (NELF) is a four subunit transcription factor. Our results point to a surprising role of NELF in the 3' end processing of histone mRNAs and suggest that NELF is a new factor that coordinates mRNA processing in transcription PMID: 17499042

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    NELF-A family
  • 組織特異性:
    Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney.
  • 數據庫鏈接:

    HGNC: 12768

    OMIM: 606026

    KEGG: hsa:7469

    STRING: 9606.ENSP00000372335

    UniGene: Hs.21771



主站蜘蛛池模板: 日韩亚洲国产激情一区浪潮av| 18禁亚洲深夜福利入口| 秋霞在线观看片无码免费不卡| 久久久无码精品亚洲日韩啪啪网站| 97精品国产一区二区三区| 最近免费中文字幕大全免费版视频 | 亚洲国产综合在线观看不卡| 国产99久久久欧美黑人刘玥| 国产欧美一区二区三区在线看| 9九色桋品熟女内射| 色惰日本视频网站www| 亚洲男人最新版本天堂| 国产成人久久精品一区二区三区| 最新国产精品自在线观看| 69天堂人成无码免费视频| 国产精品爽爽ⅴa在线观看| 四虎永久在线精品免费一区二区| 国产精品美女久久久免费| 欧美乱大交av片久久123| 天堂www中文资源| а√在线中文网新版地址在线| 少女韩国电视剧在线观看完整| 天堂在线资源中文在线8| 亚洲深深色噜噜狠狠网站| 国产卡一卡二卡三| 亚洲∧v久久久无码精品| av影音先锋最大资源网| 中文字幕一区在线观看视频| 国产爆乳美女娇喘呻吟| 国产初高中生粉嫩无套第一次| 精品国产电影久久九九| 亚洲精品国产suv| 欧美激欧美啪啪片免费看| 人妻熟女一区二区aⅴ水野朝阳| 国产精品激情| 欧美人与禽zoz0性伦交| 永久黄网站色视频免费无下载| 亚洲伊人久久成人综合网| 女人高潮内射99精品| 超碰97人人做人人爱亚洲| 精品多人p群无码|