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Recombinant Human N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL), partial

  • 中文名稱(chēng):
    人PIGL重組蛋白
  • 貨號(hào):
    CSB-YP897465HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    人PIGL重組蛋白
  • 貨號(hào):
    CSB-EP897465HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    人PIGL重組蛋白
  • 貨號(hào):
    CSB-EP897465HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    人PIGL重組蛋白
  • 貨號(hào):
    CSB-BP897465HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    人PIGL重組蛋白
  • 貨號(hào):
    CSB-MP897465HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PIGL
  • Uniprot No.:
  • 別名:
    N acetylglucosaminylphosphatidylinositol deacetylase; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Phosphatidylinositol glycan anchor biosynthesis class L; Phosphatidylinositol glycan class L; Phosphatidylinositol-glycan biosynthesis class L protein; PIG-L; Pigl; PIGL_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
  • 基因功能參考文獻(xiàn):
    1. c.336-2A>G variant in PIGL associated with developmental disorder resulted in exon skipping. PMID: 28327575
    2. these findings indicate that patients with a clinical diagnosis of CHIME syndrome and a single identifiable mutation in PIGL warrant further investigation for copynumber changes involving PMID: 28371479
    3. fd hrhr rt eruj jej PMID: 25706356
    4. Whole-exome sequencing on five previously reported CHIME cases identified PIGL (N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase) as required for glycosylphosphatidylinositol anchor formation. PMID: 22444671
  • 相關(guān)疾?。?/div>
    Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation and ear anomalies syndrome (CHIME)
  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族:
    PIGL family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 8966

    OMIM: 280000

    KEGG: hsa:9487

    STRING: 9606.ENSP00000225609

    UniGene: Hs.499793



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