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PIGL Antibody, FITC conjugated

  • 中文名稱：
    PIGL兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA897465LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PIGL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PIGL
  • 別名：
    N acetylglucosaminylphosphatidylinositol deacetylase antibody; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase antibody; Phosphatidylinositol glycan anchor biosynthesis class L antibody; Phosphatidylinositol glycan class L antibody; Phosphatidylinositol-glycan biosynthesis class L protein antibody; PIG-L antibody; Pigl antibody; PIGL_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase protein (23-252AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
  • 基因功能參考文獻：
    1. c.336-2A>G variant in PIGL associated with developmental disorder resulted in exon skipping. PMID: 28327575
    2. these findings indicate that patients with a clinical diagnosis of CHIME syndrome and a single identifiable mutation in PIGL warrant further investigation for copynumber changes involving PMID: 28371479
    3. fd hrhr rt eruj jej PMID: 25706356
    4. Whole-exome sequencing on five previously reported CHIME cases identified PIGL (N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase) as required for glycosylphosphatidylinositol anchor formation. PMID: 22444671
  • 相關疾病：
    Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation and ear anomalies syndrome (CHIME)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    PIGL family
  • 數據庫鏈接：

    HGNC: 8966

    OMIM: 280000

    KEGG: hsa:9487

    STRING: 9606.ENSP00000225609

    UniGene: Hs.499793



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