在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Mitochondrial inner membrane protein (IMMT), partial

Recombinant Human Mitochondrial inner membrane protein (IMMT), partial

  • 中文名稱：
    人IMMT重組蛋白
  • 貨號：
    CSB-YP623101HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人IMMT重組蛋白
  • 貨號：
    CSB-EP623101HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人IMMT重組蛋白
  • 貨號：
    CSB-EP623101HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人IMMT重組蛋白
  • 貨號：
    CSB-BP623101HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人IMMT重組蛋白
  • 貨號：
    CSB-MP623101HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    IMMT
  • Uniprot No.：
  • 別名：
    IMMT; HMP; MIC60; MINOS2; PIG4; PIG52; MICOS complex subunit MIC60; Cell proliferation-inducing gene 4/52 protein; Mitochondrial inner membrane protein; Mitofilin; p87/89
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
  • 基因功能參考文獻：
    1. Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50. PMID: 28808085
    2. PKA-mediated phosphorylation of MIC60 negatively regulates mitochondrial clearance that is initiated by PINK1 and Parkin. PMID: 27153535
    3. Mitofilin-knockdown cells showed decreased mitochondrial membrane potential (DeltaPsim) and intracellular ATP content, which were minimally affected in CHCHD6-knockout cells. PMID: 26530328
    4. Mic60 interacted with mtDNA and was involved in the architecture of mtDNA D-loop region. Taken together, our findings reveal a previously unrecognized important role of Mic60 in mtDNA transcription. PMID: 25612828
    5. Mitofilin, a mitochondria protein, is shown to be related to cardiac hypertrophy for the first time, which enhances our understanding of the role of mitochondria in cardiac hypertrophy. PMID: 24555791
    6. Transgenic overexpression of mitofilin preserves mitochondrial structure, leading to restoration of mitochondrial function and attenuation of cardiac contractile dysfunction in the diabetic heart. PMID: 25463274
    7. APOOL is a cardiolipin-binding component of the Mitofilin/MINOS protein complex. PMID: 23704930
    8. mitofilin distinctly functions in mitochondrial cristae remodeling and controls cytochrome c release during apoptosis. PMID: 23058921
    9. CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology. PMID: 22228767
    10. The mitochondrial dysfunction induced by DISC1 deficiency was partially reversed by coexpression of Mitofilin, confirming a functional link between DISC1 and Mitofilin for the normal mitochondrial function. PMID: 20880836
    11. Data show that the nuclear matrix protein matrin 3, cytoskeletal motor protein HMP, and the circadian clock protein lark were significantly decreased in fetal Down syndrome brain. PMID: 12469345
    12. mitofilin is a critical organizer of the mitochondrial cristae morphology and thus indispensable for normal mitochondrial function PMID: 15647377
    13. role in protein import related to maintenance of mitochondrial structure is suggested; mitofilin helps regulate mitochondrial morphology and four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion.
  • 蛋白家族：
    MICOS complex subunit Mic60 family
  • 數據庫鏈接：

    HGNC: 6047

    OMIM: 600378

    KEGG: hsa:10989

    STRING: 9606.ENSP00000387262

    UniGene: Hs.148559



主站蜘蛛池模板： 亚洲另类激情综合偷自拍图| 在线观看国产午夜福利片| 国产区在线观看成人精品| 国产人妻精品午夜福利免费| 久久久久久久久久久国产| 国产精品三级国产电影| 国产乱人伦av在线麻豆a| 极品少妇小泬50pthepon| 国产精品兄妹在线观看麻豆| 亚洲中文色欧另类欧美| 波多野无码黑人在线播放| 亚洲蜜桃v妇女| √最新版天堂资源网在线| 又爽又黄无遮拦成人网站| 免费做a爰片久久毛片a片下载| 免费无码国产欧美久久18| 日日碰狠狠躁久久躁蜜桃| 丝袜自慰一区二区三区| 亚洲欧美不卡高清在线观看 | 中国女人高潮hd| 日韩一区二区三区精品| 久久亚洲精品国产精品婷婷| 精品国产午夜理论片不卡精品| 国产小呦泬泬99精品| 8av国产精品爽爽ⅴa在线观看| 国产免费无遮挡吸乳视频在线观看| 日本另类αv欧美另类aⅴ| 97人妻精品一区二区三区| 日日躁狠狠躁狠狠爱| 国产成人精品s8视频| 国产女人好紧好爽| 欧美精品亚洲精品日韩专区va| 无码日韩人妻av一区免费 | 视频久re精品在线观看| 国产人妖视频一区二区| 国产精品丝袜久久久久久不卡| 人妻丝袜无码国产一区| 特级做a爰片毛片免费看| 美女裸体跪姿扒开屁股无内裤| av毛片无码中文字幕不卡| 国产精品亚洲专区无码破解版|