在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Meteorin-like protein (METRNL)

  • 中文名稱:
    Recombinant Human Meteorin-like protein (METRNL)
  • 貨號:
    CSB-EP731035HUc7
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    METRNL
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    36.9 kDa
  • 表達區域:
    46-311aa
  • 氨基酸序列
    QYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.
  • 基因功能參考文獻:
    1. downregulation of METRNL during adipogenesis and functional induction of increased proliferation in stromal vascular fraction cells with concomitant inhibition of adipocyte differentiation may result in hypertrophic AT accumulation PMID: 27748745
    2. Overexpression of METRNL inhibited mineralized nodule formation. PMID: 27716826
    3. Data suggest that there is no correlation between serum Metrnl levels and BMI (body mass index) in humans. PMID: 26307585
    4. Results show that Subfatin is a novel adipokine regulated by adipogenesis and obesity, with tissue distribution different from its homologue Meteorin PMID: 24393292
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Meteorin family
  • 組織特異性:
    Highly expressed in the skeletal muscle, in subcutaneous adipose tissue, epididymal white adipose tissue depots and heart. Also expressed in brown adipose tissues and kidney.
  • 數據庫鏈接:

    HGNC: 27584

    OMIM: 616241

    KEGG: hsa:284207

    STRING: 9606.ENSP00000315731

    UniGene: Hs.378821



主站蜘蛛池模板: av中文无码韩国亚洲色偷偷| 国产欧美日韩国产高清| 人人爽久久涩噜噜噜av| 国语对白嫖老妇胖老太| 人妻av无码中文专区久久| 亚洲国产av无码精品| 久久精品国产99国产精品导航| 老色鬼永久视频网站| 亚洲色大成网站www永久在线观看| 亚洲国产婷婷综合在线精品| 肥老熟妇伦子伦456视频| 欲香欲色天天天综合和网| 亚洲中文字幕av无码区| 黑人与人妻无码中字视频| 99久久国产综合精品成人影院| 对白脏话肉麻粗话av| 日韩丝袜欧美人妻制服| 午夜亚洲国产理论片中文飘花| 成人做受120秒试看试看视频| 欧洲熟妇色xxxx欧美老妇多毛| 初尝人妻少妇中文字幕| 熟女人妻少妇精品视频| 又粗又黄又爽视频免费看| 肥臀熟女一区二区三区| 级r片内射在线视频播放| 亚洲aⅴ无码专区在线观看| 国产成人av性色在线影院色戒| 中国极品少妇videossexhd| 欧美一区二区| 欧美性猛交xxx嘿人猛交| 亚洲成av人片在线观l看福利1| 特级做a爰片毛片免费69| 少妇被粗大的猛进69视频| 国内精品乱码卡一卡2卡麻豆| 久久精品人妻无码专区| 日本japanese丰满少妇| 国产97在线 | 日韩| 人人揉揉揉香蕉大免费| 人妻无码久久一区二区三区免费| 国产成人无码a区在线观看导航| 欧洲美洲精品一区二区三区 |