在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Meteorin-like protein (METRNL)

  • 中文名稱:
    人METRNL重組蛋白
  • 貨號:
    CSB-EP731035HUe0
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    METRNL
  • Uniprot No.:
  • 別名:
    (Subfatin)
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full?Length?of?Mature?Protein
  • 來源:
    E.coli
  • 分子量:
    56.6 kDa
  • 表達區域:
    46-311aa
  • 氨基酸序列
    QYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.
  • 基因功能參考文獻:
    1. downregulation of METRNL during adipogenesis and functional induction of increased proliferation in stromal vascular fraction cells with concomitant inhibition of adipocyte differentiation may result in hypertrophic AT accumulation PMID: 27748745
    2. Overexpression of METRNL inhibited mineralized nodule formation. PMID: 27716826
    3. Data suggest that there is no correlation between serum Metrnl levels and BMI (body mass index) in humans. PMID: 26307585
    4. Results show that Subfatin is a novel adipokine regulated by adipogenesis and obesity, with tissue distribution different from its homologue Meteorin PMID: 24393292
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Meteorin family
  • 組織特異性:
    Highly expressed in the skeletal muscle, in subcutaneous adipose tissue, epididymal white adipose tissue depots and heart. Also expressed in brown adipose tissues and kidney.
  • 數據庫鏈接:

    HGNC: 27584

    OMIM: 616241

    KEGG: hsa:284207

    STRING: 9606.ENSP00000315731

    UniGene: Hs.378821



主站蜘蛛池模板: 成人做爰视频www网站| 99久无码中文字幕一本久道| 免费国产乱理伦片在线观看| 国产明星裸体xxxx视频| 中文字幕亚洲欧美在线不卡 | 精品无码日韩一区二区三区不卡| 欧美午夜片欧美片在线观看| 天码人妻一区二区三区| 色婷婷综合中文久久一本| 乱人伦中文视频在线| 国产乱人伦偷精品视频免| 丰满人妻被黑人连续中出| 国产剧情av麻豆香蕉精品| 午夜理论在线观看不卡大地影院| 欧美变态另类牲交| 嫩草伊人久久精品少妇av| 女人大荫蒂毛茸茸视频| 99re6热精品视频在线观看| 欧美精品18videosex性欧| 99国产精品永久免费视频| 亚洲欧美日本韩国| 亚洲精品无码你懂的| 五月天激情婷婷婷久久| 国产韩国精品一区二区三区久久| 忘忧草日本在线www| 两个男人吮她的花蒂和奶水视频| 亚洲人成网站色7799| 无码任你躁久久久久久久| 欧美亚洲日本国产黑白配| 亚洲美女被黑人巨大在线播放| 久久综合五月丁香六月丁香 | 最近2019中文字幕大全第二页 | 99久久综合狠狠综合久久| 黑人尾随强伦姧人妻爽翻天| 色婷婷亚洲一区二区综合| 国产成人av无码精品| 国产丝袜无码一区二区视频| 无码伊人66久久大杳蕉网站谷歌 | 小说区 综合区 首页| 国产卡一卡二无线乱码| 亚洲五月综合缴情在线|