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Recombinant Human Leucine-rich repeat LGI family member 2 (LGI2)

  • 中文名稱:
    人LGI2重組蛋白
  • 貨號:
    CSB-YP822674HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人LGI2重組蛋白
  • 貨號:
    CSB-EP822674HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人LGI2重組蛋白
  • 貨號:
    CSB-BP822674HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人LGI2重組蛋白
  • 貨號:
    CSB-MP822674HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LGI2
  • Uniprot No.:
  • 別名:
    LGI2; KIAA1916; LGIL2Leucine-rich repeat LGI family member 2; LGI1-like protein 2; Leucine-rich glioma-inactivated protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    29-545
  • 氨基酸序列
    QV RRLARCPATC SCTKESIICV GSSWVPRIVP GDISSLSLVN GTFSEIKDRM FSHLPSLQLL LLNSNSFTII RDDAFAGLFH LEYLFIEGNK IETISRNAFR GLRDLTHLSL ANNHIKALPR DVFSDLDSLI ELDLRGNKFE CDCKAKWLYL WLKMTNSTVS DVLCIGPPEY QEKKLNDVTS FDYECTTTDF VVHQTLPYQS VSVDTFNSKN DVYVAIAQPS MENCMVLEWD HIEMNFRSYD NITGQSIVGC KAILIDDQVF VVVAQLFGGS HIYKYDESWT KFVKFQDIEV SRISKPNDIE LFQIDDETFF VIADSSKAGL STVYKWNSKG FYSYQSLHEW FRDTDAEFVD IDGKSHLILS SRSQVPIILQ WNKSSKKFVP HGDIPNMEDV LAVKSFRMQN TLYLSLTRFI GDSRVMRWNS KQFVEIQALP SRGAMTLQPF SFKDNHYLAL GSDYTFSQIY QWDKEKQLFK KFKEIYVQAP RSFTAVSTDR RDFFFASSFK GKTKIFEHII VDLSL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells.
  • 基因功能參考文獻:
    1. The similarity of LGI2 share a common molecular disease mechanism causing genotypically distinct but phenotypically related forms of epilepsy. PMID: 20863412
    2. protein sequence analysis and patient-specific chromosomal deletions are provided for LGI2 as the prime candidate gene for partial epilepsy with pericentral spikes among the 52 genes known at locus 4p15 PMID: 20183877
  • 亞細胞定位:
    Secreted.
  • 組織特異性:
    Brain, heart and placenta.
  • 數據庫鏈接:

    HGNC: 18710

    OMIM: 608301

    KEGG: hsa:55203

    STRING: 9606.ENSP00000371548

    UniGene: Hs.12488



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