在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Kinesin-like protein KIF2B (KIF2B)

  • 中文名稱:
    人KIF2B重組蛋白
  • 貨號:
    CSB-YP839797HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人KIF2B重組蛋白
  • 貨號:
    CSB-EP839797HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人KIF2B重組蛋白
  • 貨號:
    CSB-EP839797HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人KIF2B重組蛋白
  • 貨號:
    CSB-BP839797HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人KIF2B重組蛋白
  • 貨號:
    CSB-MP839797HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    KIF2B
  • Uniprot No.:
  • 別名:
    KIF2BKinesin-like protein KIF2B
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-673
  • 氨基酸序列
    MASQFCLPES PCLSPLKPLK PHFGDIQEGI YVAIQRSDKR IHLAVVTEIN RENYWVTVEW VEKAVKKGKK IDLETILLLN PALDSAEHPM PPPPLSPLAL APSSAIRDQR TATKWVAMIP QKNQTASGDS LDVRVPSKPC LMKQKKSPCL WEIQKLQEQR EKRRRLQQEI RARRALDVNT RNPNYEIMHM IEEYRRHLDS SKISVLEPPQ EHRICVCVRK RPLNQRETTL KDLDIITVPS DNVVMVHESK QKVDLTRYLQ NQTFCFDHAF DDKASNELVY QFTAQPLVES IFRKGMATCF AYGQTGSGKT YTMGGDFSGT AQDCSKGIYA LVAQDVFLLL RNSTYEKLDL KVYGTFFEIY GGKVYDLLNW KKKLQVLEDG NQQIQVVGLQ EKEVCCVEEV LNLVEIGNSC RTSRQTPVNA HSSRSHAVFQ IILKSGRIMH GKFSLVDLAG NERGADTTKA SRKRQLEGAE INKSLLALKE CILALGQNKP HTPFRASKLT LVLRDSFIGQ NSSTCMIATI SPGMTSCENT LNTLRYANRV KKLNVDVRPY HRGHYPIGHE APRMLKSHIG NSEMSLQRDE FIKIPYVQSE EQKEIEEVET LPTLLGKDTT ISGKGSSQWL ENIQERAGGV HHDIDFCIAR SLSILEQKID ALTEIQKKLK LLLADLHVKS KVE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Plays a role in chromosome congression.
  • 基因功能參考文獻:
    1. GSK3beta-SKAP-Kif2b signaling axis constitutes a dynamic link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. PMID: 27982129
    2. Data indicate that Cep170 association with the C-terminus of Kif2b enhances localization of Kif2b to the spindle. PMID: 23087211
    3. Data show that Polo-like kinase 1 (Plk1) regulates both the localization and activity of kinesin-13 protein Kif2b during mitosis to promote the correction of k-MT attachment errors to ensure mitotic fidelity. PMID: 22535524
    4. Data show that CLASP1-astrin-Kif2b complex acts as a central switch at kinetochores that defines mitotic progression and promotes fidelity by temporally regulating kinetochore-microtuble attachments. PMID: 20852589
    5. when microtubules are absent, the neck linker exists in equilibrium between two structural states; microtubule binding may activate the nucleotide-sensing mechanism of kinesin PMID: 12368902
    6. kinesin-I-dependent neuronal AbetaPP transport, which controls AbetaPP processing, may be regulated by JIP1 PMID: 12893827
    7. These data demonstrate that Kif2b function is required for spindle assembly and chromosome movement and that the microtubule depolymerase activities of Kif2a, Kif2b, and MCAK fulfill distinct functions during mitosis in human cells. PMID: 17538014
    8. Here we show that two microtubule-depolymerizing kinesins, Kif2b and MCAK, stimulate kinetochore-microtubule dynamics during distinct phases of mitosis to correct mal-orientations. PMID: 19060894

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Association with kinetochore is transient.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, MCAK/KIF2 subfamily
  • 組織特異性:
    Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level).
  • 數據庫鏈接:

    HGNC: 29443

    OMIM: 615142

    KEGG: hsa:84643

    STRING: 9606.ENSP00000268919

    UniGene: Hs.226805



主站蜘蛛池模板: 天干天干天啪啪夜爽爽av| 日本免费高清线视频免费| 亚洲天天做日日做天天谢日日欢| 人人妻人人爽人人做夜欢视频| 2021国产精品视频网站| 精品av一区二区久久久| 4444亚洲人成无码网在线观看| 学生妹亚洲一区二区| 黑人狠狠的挺身进入| 亚洲va中文字幕无码久久不卡| 免费无码av一区二区三区| 全球av集中精品导航福利| 日本高清一二三不卡区| 最近中文字幕免费mv在线| 亚州中文字幕午夜福利电影| 少妇高潮一区二区三区99| 欧美激情一区二区三区| 120秒试看无码体验区| 日韩精品无码熟人妻视频| 丰满爆乳一区二区三区| 日韩国产高清一区二区| 中文字幕丰满乱子无码视频| 国产人成视频在线观看| 中文在线最新版天堂| 久久亚洲精品成人av二次元| √最新版天堂资源网在线下载| 伊人久久无码中文字幕| 亚洲情xo亚洲色xo无码| 亚洲综合精品成人| 97精品超碰一区二区三区| 亚洲人成在线观看| 亚洲va天堂va欧美ⅴa在线| 精品一区二区三区在线播放视频| 欧美肉大捧一进一出免费视频| 国语精品福利自产拍在线观看| 久久99日韩国产精品久久99| 国产精品免费视频网站| 成人做爰免费视频免费看| 国产xxx视频在线观看软件| 久久国产成人精品av| 久久久亚洲欧洲日产国码农村|