在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KIF2B Antibody

  • 中文名稱:
    KIF2B兔多克隆抗體
  • 貨號:
    CSB-PA839797DSR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: KIF2B antibody at 3.59μg/ml
      Lane 1: Mouse lung tissue
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 76 kDa
      Observed band size: 80, 150 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA839797DSR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) KIF2B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KIF2B
  • 別名:
    KIF2BKinesin-like protein KIF2B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Kinesin-like protein KIF2B protein (544-673AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Plays a role in chromosome congression.
  • 基因功能參考文獻:
    1. GSK3beta-SKAP-Kif2b signaling axis constitutes a dynamic link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. PMID: 27982129
    2. Data indicate that Cep170 association with the C-terminus of Kif2b enhances localization of Kif2b to the spindle. PMID: 23087211
    3. Data show that Polo-like kinase 1 (Plk1) regulates both the localization and activity of kinesin-13 protein Kif2b during mitosis to promote the correction of k-MT attachment errors to ensure mitotic fidelity. PMID: 22535524
    4. Data show that CLASP1-astrin-Kif2b complex acts as a central switch at kinetochores that defines mitotic progression and promotes fidelity by temporally regulating kinetochore-microtuble attachments. PMID: 20852589
    5. when microtubules are absent, the neck linker exists in equilibrium between two structural states; microtubule binding may activate the nucleotide-sensing mechanism of kinesin PMID: 12368902
    6. kinesin-I-dependent neuronal AbetaPP transport, which controls AbetaPP processing, may be regulated by JIP1 PMID: 12893827
    7. These data demonstrate that Kif2b function is required for spindle assembly and chromosome movement and that the microtubule depolymerase activities of Kif2a, Kif2b, and MCAK fulfill distinct functions during mitosis in human cells. PMID: 17538014
    8. Here we show that two microtubule-depolymerizing kinesins, Kif2b and MCAK, stimulate kinetochore-microtubule dynamics during distinct phases of mitosis to correct mal-orientations. PMID: 19060894

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Association with kinetochore is transient.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, MCAK/KIF2 subfamily
  • 組織特異性:
    Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level).
  • 數據庫鏈接:

    HGNC: 29443

    OMIM: 615142

    KEGG: hsa:84643

    STRING: 9606.ENSP00000268919

    UniGene: Hs.226805



主站蜘蛛池模板: 影音先锋无码aⅴ男人资源站| 玩50岁四川熟女大白屁股直播| 国产日韩一区二区三区在线观看| 成人精品视频99在线观看免费| 久久精品国产精品青草| 欧洲vat一区二区三区| 丰满少妇被猛烈进入av久久| 国产乱人伦精品一区二区在线观看| 国产精品人人爽人人做我的可爱| 欧美亚洲国产精品久久蜜芽| 亚洲国产制服丝袜先锋| 亚洲高清毛片一区二区| 非洲黑人最猛性xxxx交| 日韩在线永久免费播放| 无码精品久久久天天影视| 乌克兰少妇xxxx做受| 俺也来俺也去俺也射| 色综合天天综合高清网国产在线| 青青草在在观免费福利线观看| 国产精品久久久午夜夜伦鲁鲁| 国产精品多人p群无码| 久久亚洲精品成人无码网站夜色 | 欧美日韩一区二区三区自拍| 成年片色大黄全免费网站久久| 99国产精品欧美一区二区三区 | 国内精品伊人久久久久777| 一本之道av不卡精品| 一本加勒比hezyo中文无码| 免费中文熟妇在线影片| 麻豆文化传媒精品一区观看| 成 人影片 免费观看在线| 欧美综合天天夜夜久久| yw尤物av无码国产在线观看| 免费国产黄网在线观看| 久久久精品94久久精品| 欧美刺激性大交| 成年无码动漫av片在线尤物| 亚洲欧美日韩国产自偷| 国产精品久线在线观看| 国产丝袜无码一区二区视频| 色哟哟最新在线观看入口|