在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Kinesin-like protein KIF17 (KIF17), partial

Recombinant Human Kinesin-like protein KIF17 (KIF17), partial

  • 中文名稱：
    人KIF17重組蛋白
  • 貨號：
    CSB-YP865208HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人KIF17重組蛋白
  • 貨號：
    CSB-EP865208HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人KIF17重組蛋白
  • 貨號：
    CSB-EP865208HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人KIF17重組蛋白
  • 貨號：
    CSB-BP865208HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人KIF17重組蛋白
  • 貨號：
    CSB-MP865208HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    KIF17
  • Uniprot No.：
  • 別名：
    KIAA1405; KIF 17; KIF 17B; KIF 3 related motor protein; KIF 3X; KIF17; KIF17_HUMAN; KIF17B; KIF3 related motor protein ; KIF3-related motor protein; KIF3X; Kinesin family member 17; Kinesin like protein KIF 17; Kinesin like protein KIF17; Kinesin-like protein KIF17
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Dendrite-specific motor protein which, in association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
  • 基因功能參考文獻：
    1. The rate of transport is set by an equilibrium between a faster state, where only kinesin family member 17 protein (KIF17) motors move the train, and a slower state, where at least one kinesin family member 3A/B protein (KIF3AB) motor on the train remains active in transport. PMID: 28761002
    2. In mammalian cells, KIF17 is dispensable for ciliogenesis and IFT-B trafficking but requires IFT-B, as well as its NLS, for its ciliary entry across the permeability barrier located at the ciliary base. PMID: 28077622
    3. The first evidence of an interaction between septins and a nonmitotic kinesin is provided and it is suggested that SEPT9 modulates the interactions of KIF17 with membrane cargo. PMID: 26823018
    4. KIF17 can modify RhoA-GTPase signaling to influence junctional actin and the stability of the apical junctional complex of epithelial cells. PMID: 26759174
    5. Expression of KIF17 in schizophrenic postmortem brains was significantly lower than controls. Both genotypic distribution and allelic frequency of rs2296225 polymorphism were significantly different between the chronic schizophrenia subjects and controls. PMID: 26421900
    6. although EB1 and KIF17-Tail may coordinate KIF17 catalytic activity, our data reveal a novel and direct role for KIF17 in regulating MT dynamics. PMID: 24072717
    7. This study suggested that disruption of KIF17, although rare, could result in a schizophrenia phenotype and emphasize the possible involvement of rare de novo mutations in this disorder. PMID: 20646681
    8. Depletion of KIF17 from cells growing in three-dimensional matrices results in aberrant epithelial cysts that fail to generate a single central lumen and to polarize apical markers. PMID: 20696710
    9. Data show that the homodimeric kinesin-2 motor KIF17 is kept in an inactive state in the absence of cargo, and define two molecular mechanisms that contribute to autoinhibition of KIF17. PMID: 20530208
    10. The intense placental expression of KIFC1 in syncytiotrophoblast and KIF17 in vascular endothelium suggests that both proteins might be important in a cargo-transport system. KIFC1 and KIF17 expression are increased of both in preeclamptia and diabetes. PMID: 19679349
    11. KIF17b serves as a molecular motor component of a TB-RBP-mouse ribonucleoprotein complex transporting a group of specific CREM-regulated mRNAs. PMID: 14673085

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cell projection, cilium. Cell projection, dendrite.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 數據庫鏈接：

    HGNC: 19167

    OMIM: 605037

    KEGG: hsa:57576

    STRING: 9606.ENSP00000247986

    UniGene: Hs.130411



主站蜘蛛池模板： 国产精品白丝喷浆| 成人免费一区二区三区视频| 国产在线精品无码二区| 国产av福利久久| 日韩av片无码一区二区不卡电影| 真实的国产乱xxxx在线| 高潮喷水无码av亚洲| 中国china体内裑精亚洲日本| 无码午夜福利片| 成人免费777777被爆出| 国内揄拍国内精品对白86| 2021年精品国产福利在线| 精品久久久久久久无码| 美女国产毛片a区内射| 无码人妻精品中文字幕不卡| h无码精品3d动漫在线观看| 亚洲 小说 欧美 激情 另类| 俄罗斯美女真人性做爰| 久久天天躁夜夜躁狠狠85台湾| 日韩视频 中文字幕 视频一区| 色135综合网| 国产成+人+综合+亚洲欧美丁香花 欧美性黑人极品hd另类 | 天天做天天大爽天天爱| 成年女人片免费视频播放a| 国产精品无码av一区二区三区| 精品无码中文视频在线观看| 亚洲中文字幕码在线电影| 日本 精品 高清不卡| 大桥久未无码吹潮在线观看 | 国产精品视频一区二区亚瑟| 99热成人精品热久久| 亚洲中文字幕无码久久精品1| 亚洲国产成人精品无码区软件| 午夜人成免费视频| 天天综合网天天综合色| 人妻换人妻仑乱| 一区二区狠狠色丁香久久婷婷| 老司机在线精品视频播放| 囯产精品一品二区三区| 成熟女人特级毛片www免费| 亚洲а∨精品天堂在线|