在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KIF17 Antibody

  • 中文名稱:
    KIF17兔多克隆抗體
  • 貨號(hào):
    CSB-PA012314GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    KIF17
  • 別名:
    KIAA1405 antibody; KIF 17 antibody; KIF 17B antibody; KIF 3 related motor protein antibody; KIF 3X antibody; KIF17 antibody; KIF17_HUMAN antibody; KIF17B antibody; KIF3 related motor protein antibody; KIF3-related motor protein antibody; KIF3X antibody; Kinesin family member 17 antibody; Kinesin like protein KIF 17 antibody; Kinesin like protein KIF17 antibody; Kinesin-like protein KIF17 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human KIF17
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Dendrite-specific motor protein which, in association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
  • 基因功能參考文獻(xiàn):
    1. The rate of transport is set by an equilibrium between a faster state, where only kinesin family member 17 protein (KIF17) motors move the train, and a slower state, where at least one kinesin family member 3A/B protein (KIF3AB) motor on the train remains active in transport. PMID: 28761002
    2. In mammalian cells, KIF17 is dispensable for ciliogenesis and IFT-B trafficking but requires IFT-B, as well as its NLS, for its ciliary entry across the permeability barrier located at the ciliary base. PMID: 28077622
    3. The first evidence of an interaction between septins and a nonmitotic kinesin is provided and it is suggested that SEPT9 modulates the interactions of KIF17 with membrane cargo. PMID: 26823018
    4. KIF17 can modify RhoA-GTPase signaling to influence junctional actin and the stability of the apical junctional complex of epithelial cells. PMID: 26759174
    5. Expression of KIF17 in schizophrenic postmortem brains was significantly lower than controls. Both genotypic distribution and allelic frequency of rs2296225 polymorphism were significantly different between the chronic schizophrenia subjects and controls. PMID: 26421900
    6. although EB1 and KIF17-Tail may coordinate KIF17 catalytic activity, our data reveal a novel and direct role for KIF17 in regulating MT dynamics. PMID: 24072717
    7. This study suggested that disruption of KIF17, although rare, could result in a schizophrenia phenotype and emphasize the possible involvement of rare de novo mutations in this disorder. PMID: 20646681
    8. Depletion of KIF17 from cells growing in three-dimensional matrices results in aberrant epithelial cysts that fail to generate a single central lumen and to polarize apical markers. PMID: 20696710
    9. Data show that the homodimeric kinesin-2 motor KIF17 is kept in an inactive state in the absence of cargo, and define two molecular mechanisms that contribute to autoinhibition of KIF17. PMID: 20530208
    10. The intense placental expression of KIFC1 in syncytiotrophoblast and KIF17 in vascular endothelium suggests that both proteins might be important in a cargo-transport system. KIFC1 and KIF17 expression are increased of both in preeclamptia and diabetes. PMID: 19679349
    11. KIF17b serves as a molecular motor component of a TB-RBP-mouse ribonucleoprotein complex transporting a group of specific CREM-regulated mRNAs. PMID: 14673085

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm, cytoskeleton. Cell projection, cilium. Cell projection, dendrite.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 19167

    OMIM: 605037

    KEGG: hsa:57576

    STRING: 9606.ENSP00000247986

    UniGene: Hs.130411



主站蜘蛛池模板: 日本黄页网站免费大全| 99国产欧美另类久久久精品| 啪啪激情婷婷久久婷婷色五月| 国产作爱视频免费播放| 一个人看的www片免费高清视频| 红杏亚洲影院一区二区三区| 免费无码黄动漫十八禁| 午夜dy888国产精品影院| 久久精品www人人爽人人| 青娱乐极品视觉盛宴国产视频| 麻豆自媒体 一区 二区| 欧美日韩精品一区二区性色a+v| www夜插内射视频网站| 欧美人与禽zoz0性伦交| 夜夜澡人摸人人添人人看| 国产成人精品免费午夜app| 精产国品一二三产区m553麻豆| 成人免费无遮挡无码黄漫视频 | 亚洲6080yy久久无码产自国产| 久久av无码精品人妻系列| 亚洲精品国产嫩草在线观看东京热 | 国产欧美日韩另类在线专区| 人妻三级日本香港三级极97| 日韩av无码中文无码不卡电影| 97久久久久人妻精品区一| 成 人影片 免费观看在线| 四虎av永久在线精品免费观看| 国产9 9在线 | 中文| 国产aⅴ爽av久久久久久| 少妇午夜av一区| 业余 自由 性别 成熟偷窥| 一本一道vs无码中文字幕| 国产亚洲精品自在久久蜜tv| 性色av免费网站| 99久久精品美女高潮喷水| 四十如虎的丰满熟妇啪啪| av小次郎收藏| 日日拍夜夜嗷嗷叫国产| 国模无码一区二区三区不卡| 毛片内射-百度| 亚洲欧美日韩精品色xxx|