在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Islet cell autoantigen 1 (ICA1), partial

  • 中文名稱:
    人ICA1重組蛋白
  • 貨號:
    CSB-EP010947HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ICA1
  • Uniprot No.:
  • 別名:
    69 kDa islet cell autoantigen; Diabetes mellitus type I autoantigen; ICA 1; Ica1; ICA69; ICA69_HUMAN; ICAp69; Islet cell autoantigen 1 (69kD); Islet cell autoantigen 1 69kDa; Islet cell autoantigen 1; Islet cell autoantigen 1 isoform; Islet cell autoantigen p69; OTTHUMP00000200933; OTTHUMP00000200934; OTTHUMP00000200941; OTTHUMP00000200993; p69
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    35.5kDa
  • 表達區域:
    1-268aa
  • 氨基酸序列
    MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play a role in neurotransmitter secretion.
  • 基因功能參考文獻:
    1. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCalpha complex and cerebellar plasticity. PMID: 24358315
    2. Novel association was found between intraocular pressure and a common variant at 7p21 near to GLCCI1 and ICA1. PMID: 23836780
    3. polymorphisms within the NOD Ica1 core promoter may determine AIRE-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells. PMID: 22447927
    4. The exon A promoter exhibits greater activity in islet cells, whereas the exon B promoter more efficiently activates transcription in neuronal cells. PMID: 12409289
    5. ICA69 as a novel Rab2 effector and its role in regulating the early transport of insulin secretory granule proteins PMID: 18187231

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
  • 組織特異性:
    Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
  • 數據庫鏈接:

    HGNC: 5343

    OMIM: 147625

    KEGG: hsa:3382

    STRING: 9606.ENSP00000379908

    UniGene: Hs.487561



主站蜘蛛池模板: 99久久久国产精品免费蜜臀| 国产精品人妻一区二区高| 中文字幕人妻互换av久久| 国产精品久久久久久久久久久久| 国内精品久久久久久久影视| 久久久久久成人综合网| 国产欧美日本亚洲精品一5区| 色老板精品视频在线观看| 18禁成年免费无码国产| 欧美人妻体内射射| 亚洲精品国产一区二区的区别| 国产男女猛烈无遮挡免费网站| 熟妇熟女乱妇乱女网站| 日本午夜免a费看大片中文4| 亚洲国产成人精品无码区在线| 欧美肥胖老妇bbw| 国产精品福利视频萌白酱| 日产精品一卡2卡三卡4乱码| 精品国产乱码一区二区三区| 无码国产精成人午夜视频一区二区| 色8激情欧美成人久久综合电影| 人人爽人人添人人超| 77777_亚洲午夜久久多人| 性一交一无一伦一精一品| 欧美乱大交aaaa片if| 中文字幕日韩人妻无码| 18禁男女爽爽爽午夜网站免费| 成人午夜无码专区性视频性视频 | 久久久久99精品成人片三人毛片| 国产精品一卡二卡三卡| 日日婷婷夜日日天干| 99在线精品视频观看免费| 无码av波多野结衣| 亚洲毛片无码不卡av在线播放| 国产亚洲色欲色一色www| 午夜精品久久久久久久| 久久人人爽人人爽人人片dvd| 2021久久超碰国产精品最新| 日本猛少妇色xxxxx猛叫| 国产真实露脸乱子伦原著| 亚洲 一区二区 在线|