在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Islet cell autoantigen 1 (ICA1)

In Stock
  • 中文名稱:
    人ICA1重組蛋白
  • 貨號(hào):
    CSB-YP010947HU(F1)
  • 規(guī)格:
    ¥1656
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • The purity of ICA1 was greater than 90% as determined by SEC-HPLC
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
    Greater than 90% as determined by SEC-HPLC.
  • 基因名:
    ICA1
  • Uniprot No.:
  • 別名:
    69 kDa islet cell autoantigen; Diabetes mellitus type I autoantigen; ICA 1; Ica1; ICA69; ICA69_HUMAN; ICAp69; Islet cell autoantigen 1 (69kD); Islet cell autoantigen 1 69kDa; Islet cell autoantigen 1; Islet cell autoantigen 1 isoform; Islet cell autoantigen p69; OTTHUMP00000200933; OTTHUMP00000200934; OTTHUMP00000200941; OTTHUMP00000200993; p69
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length of Isoform 3
  • 來源:
    Yeast
  • 分子量:
    56.6kDa
  • 表達(dá)區(qū)域:
    1-482aa
  • 氨基酸序列
    MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May play a role in neurotransmitter secretion.
  • 基因功能參考文獻(xiàn):
    1. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCalpha complex and cerebellar plasticity. PMID: 24358315
    2. Novel association was found between intraocular pressure and a common variant at 7p21 near to GLCCI1 and ICA1. PMID: 23836780
    3. polymorphisms within the NOD Ica1 core promoter may determine AIRE-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells. PMID: 22447927
    4. The exon A promoter exhibits greater activity in islet cells, whereas the exon B promoter more efficiently activates transcription in neuronal cells. PMID: 12409289
    5. ICA69 as a novel Rab2 effector and its role in regulating the early transport of insulin secretory granule proteins PMID: 18187231

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
  • 組織特異性:
    Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5343

    OMIM: 147625

    KEGG: hsa:3382

    STRING: 9606.ENSP00000379908

    UniGene: Hs.487561



主站蜘蛛池模板: 国产乱人伦偷精品视频aaa| 国产亚洲精品综合一区| 丰满无码人妻热妇无码区| 亚洲久久久久久中文字幕| 欧美深度肠交惨叫| 欧美v国产v亚洲v日韩九九| 一本之道高清乱码久久久| 无码中文人妻在线一区| 特级a欧美做爰片第一次| 午夜精品久久久久久久喷水| 狠狠躁夜夜躁人人爽天天天天97| 无码人妻久久一区二区三区不卡| 久久综合久久88中字幕文| 777米奇影院狠狠色| 亚洲精品久久久久久久蜜桃臀| 国产av一区二区三区传媒| 麻豆久久久9性大片| 亚洲精品无码不卡在线播放he| 日本国产制服丝袜一区| 男女猛烈xx00免费视频试看| 一本色综合网久久| 精品国产免费第一区二区三区| 2018高清国产一区二区三区| 亚洲熟妇丰满多毛xxxx| 么公的好大好硬好深好爽视频| 久久精品免费国产大片| 人妻精品久久无码区| 人与嘼av免费| 鲁大师影院在线观看| 亚洲人成网站在线播放小说| 成人无码专区免费播放三区| 亚洲国产精久久久久久久| 超碰97人人射妻| 国产亚洲精品久久久性色情软件 | 1000部夫妻午夜免费| 国产免费视频| 国产成人片无码免费视频| 亚洲中文字幕a∨在线| 久久婷婷成人综合色综合| 99久久国产综合精品swag | 欧美丰满熟妇bbb久久久|