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Recombinant Human Interphotoreceptor matrix proteoglycan 2 (IMPG2), partial

  • 中文名稱:
    人IMPG2重組蛋白
  • 貨號:
    CSB-YP011704HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人IMPG2重組蛋白
  • 貨號:
    CSB-EP011704HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人IMPG2重組蛋白
  • 貨號:
    CSB-EP011704HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人IMPG2重組蛋白
  • 貨號:
    CSB-BP011704HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人IMPG2重組蛋白
  • 貨號:
    CSB-MP011704HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    IMPG2
  • Uniprot No.:
  • 別名:
    IMPG2; IPM200; Interphotoreceptor matrix proteoglycan 2; Interphotoreceptor matrix proteoglycan of 200 kDa; IPM 200; Sialoprotein associated with cones and rods proteoglycan; Spacrcan
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.
  • 基因功能參考文獻:
    1. IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families. PMID: 25085631
    2. Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life. PMID: 24876279
    3. identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa PMID: 20673862
    4. IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival PMID: 10542133
  • 相關疾?。?/div>
    Retinitis pigmentosa 56 (RP56); Macular dystrophy, vitelliform, 5 (VMD5)
  • 亞細胞定位:
    Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
  • 組織特異性:
    Expressed in the retina (at protein level). Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones (at protein level). IPM occupies the subretinal space between the apices of the retinal pigment epithelium and t
  • 數據庫鏈接:

    HGNC: 18362

    OMIM: 607056

    KEGG: hsa:50939

    STRING: 9606.ENSP00000193391

    UniGene: Hs.209249



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